Hepatitis B vaccine (Heplisav-B) cost in Illinois
In Illinois, 39 hospitals publish a cash price for hepatitis B vaccine, adult, 2-dose schedule (Heplisav-B): from $48.51 to $1,831.62, with a median of $224.28. The lowest price is at Humboldt Park Health (Chicago). The highest price is 37.8× the lowest.
Outpatient cash prices, one line per hospital — its lowest listed price for code 90739. Prices for both sides of the body and inpatient prices are not mixed in. Collected Sep 29, 2026. See them on a map
Lowest$48.51Humboldt Park Health
Median$224.28half pay less
Highest$1,831.62in Illinois
Lowest saves$175.77vs the median
Hospitals in Illinois, cheapest first
| Hospital | Cash price | List price | File date |
|---|---|---|---|
| Humboldt Park Health lowest Chicago · Chicago-Naperville-Elgin, IL-IN Hepatitis B vaccine (HepB), CpG-adjuvanted, adult dosage, 2 dose or 4 dose schedule, for intramuscular use | $48.51 | $173.25 | Aug 24, 2026 source file |
| Gottlieb Memorial Hospital Melrose Park · Chicago-Naperville-Elgin, IL-IN Hepatitis B Adult Heplisav-B 2-Dose Sch Im Inj (Fc) | $68.21 | $359.00 | Mar 31, 2026 source file |
| MacNeal Hospital Berwyn · Chicago-Naperville-Elgin, IL-IN Hepatitis B Adult Heplisav-B 2-Dose Sch Im Inj (Fc) | $68.21 | $359.00 | Mar 31, 2026 source file |
| Loyola University Medical Center Maywood · Chicago-Naperville-Elgin, IL-IN Hepatitis B Adult Heplisav-B 2-Dose Sch Im Inj (Fc) | $82.57 | $359.00 | Mar 31, 2026 source file |
| The University of Chicago Medical Center Chicago · Chicago-Naperville-Elgin, IL-IN Hc Hepb Vacc 2 Dose Adult Im Employee Health | $145.00 | $145.00 | Apr 1, 2026 source file |
| Gibson Community Hospital Gibson City · Champaign-Urbana, IL HEP B VACC ADULT 2 DOSE IM | $150.00 | $150.00 | — source file |
| Uchicago Medicine AdventHealth Bolingbrook Bolingbrook · Chicago-Naperville-Elgin, IL-IN HEPATITIS B VAC RECOMB ADJ 20 MCG/0.5ML IM SOSY | $185.29 | $741.14 | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth Glenoaks Glendale Heights · Chicago-Naperville-Elgin, IL-IN HEPATITIS B VAC RECOMB ADJ 20 MCG/0.5ML IM SOSY | $185.29 | $741.14 | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth Hinsdale Hinsdale · Chicago-Naperville-Elgin, IL-IN HEPATITIS B VAC RECOMB ADJ 20 MCG/0.5ML IM SOSY | $185.29 | $741.14 | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth La Grange La Grange · Chicago-Naperville-Elgin, IL-IN HEPATITIS B VAC RECOMB ADJ 20 MCG/0.5ML IM SOSY | $185.29 | $741.14 | Apr 1, 2026 source file |
| Sarah Bush Lincoln Health Center Mattoon · Charleston-Mattoon, IL Hepatitis B vaccine (HepB), CpG-adjuvanted, adult dosage, 2 dose or 4 dose schedule, for intramuscular use | $202.24 | $202.24 | Jun 3, 2026 source file |
| Rockford Memorial Hospital Rockford · Rockford, IL hepatitis B vaccine rec PF 10 mcg/mL Susp 1 mL Vial | $209.55 | $279.40 | Mar 1, 2026 source file |
| NorthShore University HealthSystems Glenbrook Hospital Glenview · Chicago-Naperville-Elgin, IL-IN Hepatitis B Vacc Adult 2 Dose Im | $212.55 | $327.00 | — source file |
| NorthShore University HealthSystems Skokie Hospital Skokie · Chicago-Naperville-Elgin, IL-IN Hepatitis B Vacc Adult 2 Dose Im | $212.55 | $327.00 | — source file |
| Carle BroMenn Medical Center Normal · Bloomington, IL HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE | $224.28 | $224.28 | Apr 15, 2026 source file |
| Carle Eureka Hospital Eureka · Peoria, IL HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE | $224.28 | $224.28 | Apr 15, 2026 source file |
| Carle Health Pekin Hospital Pekin · Peoria, IL HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE | $224.28 | $224.28 | Apr 15, 2026 source file |
| Hoopeston Community Memorial Hospital Hoopeston · Danville, IL HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE | $224.28 | $224.28 | Apr 15, 2026 source file |
| Methodist Medical Center of Illinois Peoria · Peoria, IL HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE | $224.28 | $224.28 | Apr 15, 2026 source file |
| Proctor Community Hospital Peoria · Peoria, IL HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE | $224.28 | $224.28 | Apr 15, 2026 source file |
| Richland Memorial Hospital Olney · Olney, IL HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE | $224.28 | $224.28 | Apr 15, 2026 source file |
| The Carle Foundation Hospital Urbana · Champaign-Urbana, IL HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE | $224.28 | $224.28 | Apr 15, 2026 source file |
| MercyOne Genesis Aledo Medical Center Aledo · Davenport-Moline-Rock Island, IA-IL hepatitis B adult vaccine 20 mcg/0.5 mL | $273.90 | $456.50 | Mar 31, 2026 source file |
| MercyOne Genesis Silvis Medical Center Silvis · Davenport-Moline-Rock Island, IA-IL hepatitis B adult vaccine 20 mcg/0.5 mL | $273.90 | $456.50 | Mar 31, 2026 source file |
| Presence Saint Joseph Hospital - Chicago Chicago · Chicago-Naperville-Elgin, IL-IN HEPATITIS B VAC RECOMB ADJ 20 MCG/0.5ML IM SOSY | $302.43 | $916.46 | — source file |
| FHN Memorial Hospital Freeport · Freeport, IL Hepatitis B vaccine (HepB), CpG-adjuvanted, adult dosage, 2 dose or 4 dose schedule, for intramuscular use | $305.60 | $382.00 | Jan 22, 2026 source file |
| Endeavor Health Highland Park Hospital Highland Park · Chicago-Naperville-Elgin, IL-IN HEPATITIS B VACC ADULT 2 DOSE IM | $362.00 | $362.00 | Apr 1, 2026 source file |
| Northshore University Healthsystem - Evanston Hospital Evanston · Chicago-Naperville-Elgin, IL-IN HEPATITIS B VACC ADULT 2 DOSE IM | $362.00 | $362.00 | Apr 1, 2026 source file |
| Swedish Covenant Health Chicago · Chicago-Naperville-Elgin, IL-IN HEPATITIS B VACC ADULT 2 DOSE IM | $362.00 | $362.00 | Apr 1, 2026 source file |
| Northwestern Lake Forest Hospital Lake Forest · Chicago-Naperville-Elgin, IL-IN HB Heplisav Hepb Vaccine Adult 2 Dose Schedule for Im Use | $440.30 | $629.00 | Apr 1, 2026 source file |
| Northwestern Medicine Central DuPage Hospital Winfield · Chicago-Naperville-Elgin, IL-IN HB Heplisav Hepb Vaccine Adult 2 Dose Schedule for Im Use | $440.30 | $629.00 | Apr 1, 2026 source file |
| Northwestern Medicine Delnor Hospital Geneva · Chicago-Naperville-Elgin, IL-IN HB Heplisav Hepb Vaccine Adult 2 Dose Schedule for Im Use | $440.30 | $629.00 | Apr 1, 2026 source file |
| Northwestern Medicine Kishwaukee Hospital DeKalb · Chicago-Naperville-Elgin, IL-IN HB Heplisav Hepb Vaccine Adult 2 Dose Schedule for Im Use | $440.30 | $629.00 | Apr 1, 2026 source file |
| Northwestern Medicine Marianjoy Rehabilitation Hospital Wheaton · Chicago-Naperville-Elgin, IL-IN HB Heplisav Hepb Vaccine Adult 2 Dose Schedule for Im Use | $440.30 | $629.00 | Apr 1, 2026 source file |
| Northwestern Medicine McHenry Hospital McHenry · Chicago-Naperville-Elgin, IL-IN HB Heplisav Hepb Vaccine Adult 2 Dose Schedule for Im Use | $440.30 | $629.00 | Apr 1, 2026 source file |
| Northwestern Medicine Valley West Hospital Sandwich · Chicago-Naperville-Elgin, IL-IN HB Heplisav Hepb Vaccine Adult 2 Dose Schedule for Im Use | $440.30 | $629.00 | Apr 1, 2026 source file |
| Northwestern Memorial Hospital Chicago · Chicago-Naperville-Elgin, IL-IN HB Heplisav Hepb Vaccine Adult 2 Dose Schedule for Im Use | $440.30 | $629.00 | Apr 1, 2026 source file |
| Palos Community Hospital Palos Heights · Chicago-Naperville-Elgin, IL-IN HB Heplisav Hepb Vaccine Adult 2 Dose Schedule for Im Use | $440.30 | $629.00 | Apr 1, 2026 source file |
| John H. Stroger, Jr. Hospital Chicago · Chicago-Naperville-Elgin, IL-IN HEPATITIS B ADULT VACCINE (HEPLISAV-B) 20 MCG/0.5 ML | $1,831.62 | $2,616.60 | — source file |
By metro area
Each metro page compares every listing, including prices for both sides of the body.
| Metro area | Hospitals | Lowest | Median |
|---|---|---|---|
| Chicago-Naperville-Elgin, IL-IN | 25 | $48.51 | $362.00 |
| Peoria, IL | 4 | $224.28 | $224.28 |
| Champaign-Urbana, IL | 2 | $150.00 | $187.14 |
| Davenport-Moline-Rock Island, IA-IL | 2 | $273.90 | $273.90 |
| Bloomington, IL | 1 | $224.28 | $224.28 |
| Charleston-Mattoon, IL | 1 | $202.24 | $202.24 |
| Danville, IL | 1 | $224.28 | $224.28 |
| Freeport, IL | 1 | $305.60 | $305.60 |
| Olney, IL | 1 | $224.28 | $224.28 |
| Rockford, IL | 1 | $209.55 | $209.55 |
What it is
Heplisav-B is a hepatitis B vaccine for adults that needs only two doses, one month apart, instead of three over six months.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).
Hepatitis B vaccine, adult, 2-dose schedule (Heplisav-B) in other states
- Alabama$253.18
- Alaska$461.77
- Arizona$401.95
- Arkansas$186.31
- California$255.29
- Colorado$268.68
- Connecticut$277.36
- Delaware$1,124.13
- District of Columbia$284.69
- Florida$343.87
- Georgia$579.89
- Hawaii$368.21
- Idaho$198.58
- Indiana$299.04
- Iowa$306.24
- Kansas$235.37
- Kentucky$685.51
- Louisiana$138.18
- Maine$189.79
- Maryland$248.69
- Massachusetts$315.59
- Michigan$189.53
- Minnesota$162.50
- Mississippi$183.60
- Montana$168.00
- Nebraska$284.05
- Nevada$147.30
- New Hampshire$324.13
- New Jersey$138.08
- New Mexico$831.56
- New York$241.41
- North Carolina$215.14
- North Dakota$189.54
- Ohio$218.74
- Oklahoma$383.61
- Oregon$173.32
- Pennsylvania$174.16
- Rhode Island$270.00
- South Dakota$229.82
- Tennessee$169.86
- Texas$402.20
- Utah$252.28
- Vermont$314.12
- Virginia$176.53
- Washington$189.00
- West Virginia$127.00
- Wisconsin$213.85
Median cash price across the state's hospitals.