Hepatitis B vaccine (Heplisav-B) cost in South Dakota
In South Dakota, 6 hospitals publish a cash price for hepatitis B vaccine, adult, 2-dose schedule (Heplisav-B): from $106.21 to $387.48, with a median of $229.82. The lowest price is at Sanford Clear Lake Medical Center (Clear Lake). The highest price is 3.6× the lowest.
Outpatient cash prices, one line per hospital — its lowest listed price for code 90739. Prices for both sides of the body and inpatient prices are not mixed in. Collected Sep 27, 2026. See them on a map
Hospitals in South Dakota, cheapest first
| Hospital | Cash price | List price | File date |
|---|---|---|---|
| Sanford Clear Lake Medical Center lowest Clear Lake · Clear Lake, SD Hepatitis B Vaccine Recomb Adjuvanted Pref Syr 20 MCG/0.5ML | $106.21 | $132.76 | Mar 4, 2026 source file |
| Douglas County Memorial Hospital Armour · Armour, SD HEP B VACC ADULT 2 DOSE IM | $168.30 | $187.00 | Jan 9, 2026 source file |
| Sanford Vermillion Hospital Vermillion · Vermillion, SD Hepatitis B Vaccine Recomb Adjuvanted Pref Syr 20 MCG/0.5ML | $226.64 | $283.29 | Mar 4, 2026 source file |
| Monument Health Rapid City Hospital Rapid City · Rapid City, SD Hepatitis B vaccine (HepB), CpG-adjuvanted, adult dosage, 2 dose or 4 dose schedule, for intramuscular use | $233.00 | $291.25 | Sep 1, 2026 source file |
| Sanford Webster Hospital Webster · Webster, SD Hepatitis B Vaccine Recomb Adjuvanted Pref Syr 20 MCG/0.5ML | $243.76 | $304.70 | Mar 4, 2026 source file |
| Sanford USD Medical Center Sioux Falls · Sioux Falls, SD-MN Hepatitis B Vaccine Recomb Adjuvanted Pref Syr 20 MCG/0.5ML | $387.48 | $484.35 | Mar 4, 2026 source file |
By metro area
Each metro page compares every listing, including prices for both sides of the body.
| Metro area | Hospitals | Lowest | Median |
|---|---|---|---|
| Armour, SD | 1 | $168.30 | $168.30 |
| Clear Lake, SD | 1 | $106.21 | $106.21 |
| Rapid City, SD | 1 | $233.00 | $233.00 |
| Sioux Falls, SD-MN | 1 | $387.48 | $387.48 |
| Vermillion, SD | 1 | $226.64 | $226.64 |
| Webster, SD | 1 | $243.76 | $243.76 |
What it is
Heplisav-B is a hepatitis B vaccine for adults that needs only two doses, one month apart, instead of three over six months.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).
Hepatitis B vaccine, adult, 2-dose schedule (Heplisav-B) in other states
- Alabama$253.18
- Alaska$461.77
- Arizona$401.95
- Arkansas$186.31
- California$255.29
- Colorado$268.68
- Connecticut$277.36
- Delaware$1,124.13
- District of Columbia$284.69
- Florida$343.87
- Georgia$579.89
- Hawaii$368.21
- Idaho$198.58
- Illinois$224.28
- Indiana$299.04
- Iowa$306.24
- Kansas$235.37
- Kentucky$685.51
- Louisiana$138.18
- Maine$189.79
- Maryland$248.69
- Massachusetts$315.59
- Michigan$189.53
- Minnesota$162.50
- Mississippi$183.60
- Montana$168.00
- Nebraska$284.05
- Nevada$147.30
- New Hampshire$324.13
- New Jersey$138.08
- New Mexico$831.56
- New York$241.41
- North Carolina$215.14
- North Dakota$189.54
- Ohio$218.74
- Oklahoma$383.61
- Oregon$173.32
- Pennsylvania$174.16
- Rhode Island$270.00
- Tennessee$169.86
- Texas$402.20
- Utah$252.28
- Vermont$314.12
- Virginia$176.53
- Washington$189.00
- West Virginia$127.00
- Wisconsin$213.85
Median cash price across the state's hospitals.