Hepatitis B vaccine (Heplisav-B) cost in Pennsylvania
In Pennsylvania, 38 hospitals publish a cash price for hepatitis B vaccine, adult, 2-dose schedule (Heplisav-B): from $65.80 to $440.25, with a median of $174.16. The lowest price is at Wayne Memorial Hospital (Honesdale). The highest price is 6.7× the lowest.
Outpatient cash prices, one line per hospital — its lowest listed price for code 90739. Prices for both sides of the body and inpatient prices are not mixed in. Collected Sep 29, 2026. See them on a map
Hospitals in Pennsylvania, cheapest first
| Hospital | Cash price | List price | File date |
|---|---|---|---|
| Wayne Memorial Hospital lowest Honesdale · Honesdale, PA ADM OF HEP B VACCINE | $65.80 | $94.00 | Sep 16, 2026 source file |
| Canonsburg General Hospital Canonsburg · Pittsburgh, PA HEPATITIS B VACCINE 20 MCG/0.5 ML-ADJUVANT CPG 1018 (PF) IM SYRINGE | $68.53 | $311.50 | Apr 14, 2026 source file |
| UPMC Passavant - McCandless Pittsburgh · Pittsburgh, PA HC HEP B VACCINE 2 DOSE ADULT | $86.40 | $144.00 | — source file |
| UPMC Altoona Altoona · Altoona, PA HEPATITIS B VAC 20MCG/0.5 ML | $126.60 | $211.00 | — source file |
| UPMC Bedford Everett · Everett, PA HEPATITIS B VAC 20MCG/0.5 ML | $126.60 | $211.00 | — source file |
| UPMC Childrens Hospital of Pittsburgh Pittsburgh · Pittsburgh, PA HEPATITIS B VAC 20MCG/0.5 ML | $126.60 | $211.00 | Mar 6, 2026 source file |
| UPMC Hamot Erie · Erie, PA HEPLISAV-B 20MCG/0.5ML ADT | $126.60 | $211.00 | — source file |
| UPMC Jameson New Castle · Pittsburgh, PA HEPATITIS B VAC 20MCG/0.5 ML | $126.60 | $211.00 | — source file |
| UPMC Magee-Womens Hospital Pittsburgh · Pittsburgh, PA HC HEPATITIS B VAC 20MCG/0.5 ML | $126.60 | $211.00 | — source file |
| UPMC Mercy Pittsburgh · Pittsburgh, PA HEPATITIS B VAC 20MCG/0.5 ML | $126.60 | $211.00 | — source file |
| UPMC Presbyterian Pittsburgh · Pittsburgh, PA HEPATITIS B VAC 20MCG/0.5 ML | $126.60 | $211.00 | Mar 6, 2026 source file |
| UPMC St Margaret Pittsburgh · Pittsburgh, PA HEPATITIS B VAC 20MCG/0.5 ML | $126.60 | $211.00 | — source file |
| UPMC Western Psychiatric Hospital Pittsburgh · Pittsburgh, PA HEPATITIS B VAC 20MCG/0.5 ML | $126.60 | $211.00 | — source file |
| UPMC Williamsport Williamsport · Williamsport, PA HEPATITIS B VAC 20MCG/0.5 ML | $126.60 | $211.00 | — source file |
| Uniontown Hospital Uniontown · Pittsburgh, PA HEPB VACC 2/4 DOSE ADULT IM | $127.00 | $254.00 | — source file |
| Warren General Hospital Warren · Warren, PA ADMIN OF HEP B VACCINE | $160.00 | $160.00 | Sep 24, 2026 source file |
| UPMC Muncy Muncy · Williamsport, PA HEPATITIS B VAC 20MCG/0.5 ML | $168.80 | $211.00 | — source file |
| UPMC Northwest Seneca · Oil City, PA HEPATITIS B VAC 20MCG/0.5 ML | $168.80 | $211.00 | — source file |
| UPMC Wellsboro Wellsboro · Wellsboro, PA HEPATITIS B VAC 20MCG/0.5 ML | $168.80 | $211.00 | — source file |
| Indiana Regional Medical Center Indiana · Indiana, PA hepatitis B adult vaccine 20 mcg 0.5 mL Inj Soln | $179.52 | $498.67 | Feb 24, 2026 source file |
| Penn State Health Lancaster Medical Center Lancaster · Lancaster, PA hepatitis B adult vaccine (Heplisav-B) 20 mcg/0.5 mL syringe inj. | $237.05 | $817.69 | — source file |
| Armstrong County Memorial Hospital Kittanning · Pittsburgh, PA HEP B VACCINE RECOM 20MCG.5ML | $237.74 | $792.48 | Mar 2, 2026 source file |
| Robert Packer Hospital Sayre · Sayre, PA HC Fac Hepatitis B Vaccine Adult 2 Dose Im | $241.08 | $301.35 | — source file |
| Robert Packer Hospital, Towanda Campus Towanda · Sayre, PA HC Fac Hepatitis B Vaccine Adult 2 Dose Im | $241.08 | $301.35 | — source file |
| Troy Community Hospital Troy · Sayre, PA HC Fac Hepatitis B Vaccine Adult 2 Dose Im | $241.08 | $301.35 | — source file |
| Penn State Health Milton S. Hershey Medical Center Hershey · Harrisburg-Carlisle, PA hepatitis B adult vaccine (Heplisav-B) 20 mcg/0.5 mL syringe inj. | $245.10 | $739.81 | — source file |
| York Hospital York · York-Hanover, PA Hepatitis B Vaccine Cpg Adjuvanted Adult Dosage 2 or 4 Dosage Schedule | $342.40 | $428.00 | — source file |
| Penn Highlands Brookville Brookville · Brookville, PA hepatitis B adult vaccine 20 mcg/0.5 mL Sol-[PM] | $345.00 | $345.00 | Apr 1, 2026 source file |
| Penn Highlands Dubois DuBois · DuBois, PA hepatitis B adult vaccine 20 mcg/0.5 mL Sol-[PM] | $345.00 | $345.00 | Aug 1, 2025 source file |
| Penn Highlands Elk Saint Marys · St. Marys, PA hepatitis B adult vaccine 20 mcg/0.5 mL Sol-[PM] | $345.00 | $345.00 | Apr 1, 2026 source file |
| Penn Highlands Huntingdon Huntingdon · Huntingdon, PA hepatitis B adult vaccine 20 mcg/0.5 mL Sol-[PM] | $345.00 | $345.00 | Apr 1, 2026 source file |
| Penn Highlands Tyrone Tyrone · Altoona, PA hepatitis B adult vaccine 20 mcg/0.5 mL Sol-[PM] | $345.00 | $345.00 | Apr 1, 2026 source file |
| Bryn Mawr Rehabilitation Hospital Malvern · Philadelphia-Camden-Wilmington, PA-NJ-DE-MD HEPATITIS B VACCINE 20 MCG/0.5 ML-ADJUVANT CPG 1018 (PF) IM SYRINGE [175535] | $393.60 | $984.00 | — source file |
| Lankenau Medical Center Wynnewood · Philadelphia-Camden-Wilmington, PA-NJ-DE-MD HEPATITIS B VACCINE 20 MCG/0.5 ML-ADJUVANT CPG 1018 (PF) IM SYRINGE [175535] | $393.60 | $984.00 | Apr 1, 2026 source file |
| Paoli Hospital Paoli · Philadelphia-Camden-Wilmington, PA-NJ-DE-MD HEPATITIS B VACCINE 20 MCG/0.5 ML-ADJUVANT CPG 1018 (PF) IM SYRINGE [175535] | $393.60 | $984.00 | Apr 1, 2026 source file |
| Riddle Memorial Hospital Media · Philadelphia-Camden-Wilmington, PA-NJ-DE-MD HEPATITIS B VACCINE 20 MCG/0.5 ML-ADJUVANT CPG 1018 (PF) IM SYRINGE [175535] | $393.60 | $984.00 | Apr 1, 2026 source file |
| The Bryn Mawr Hospital Bryn Mawr · Philadelphia-Camden-Wilmington, PA-NJ-DE-MD HEPATITIS B VACCINE 20 MCG/0.5 ML-ADJUVANT CPG 1018 (PF) IM SYRINGE [175535] | $393.60 | $984.00 | — source file |
| Conemaugh Memorial Medical Center Johnstown · Johnstown, PA Hepatitis B vaccine (HepB), CpG-adjuvanted, adult dosage, 2 dose or 4 dose schedule, for intramuscular use | $440.25 | $1,100.62 | — source file |
By metro area
Each metro page compares every listing, including prices for both sides of the body.
| Metro area | Hospitals | Lowest | Median |
|---|---|---|---|
| Pittsburgh, PA | 11 | $68.53 | $126.60 |
| Philadelphia-Camden-Wilmington, PA-NJ-DE-MD | 5 | $393.60 | $393.60 |
| Sayre, PA | 3 | $241.08 | $241.08 |
| Altoona, PA | 2 | $126.60 | $235.80 |
| Williamsport, PA | 2 | $126.60 | $147.70 |
| Brookville, PA | 1 | $345.00 | $345.00 |
| DuBois, PA | 1 | $345.00 | $345.00 |
| Everett, PA | 1 | $126.60 | $126.60 |
| Erie, PA | 1 | $126.60 | $126.60 |
| Honesdale, PA | 1 | $65.80 | $65.80 |
| Harrisburg-Carlisle, PA | 1 | $245.10 | $245.10 |
| Huntingdon, PA | 1 | $345.00 | $345.00 |
| Indiana, PA | 1 | $179.52 | $179.52 |
| Johnstown, PA | 1 | $440.25 | $440.25 |
| Lancaster, PA | 1 | $237.05 | $237.05 |
| Oil City, PA | 1 | $168.80 | $168.80 |
| St. Marys, PA | 1 | $345.00 | $345.00 |
| Wellsboro, PA | 1 | $168.80 | $168.80 |
| Warren, PA | 1 | $160.00 | $160.00 |
| York-Hanover, PA | 1 | $342.40 | $342.40 |
What it is
Heplisav-B is a hepatitis B vaccine for adults that needs only two doses, one month apart, instead of three over six months.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).
Hepatitis B vaccine, adult, 2-dose schedule (Heplisav-B) in other states
- Alabama$253.18
- Alaska$461.77
- Arizona$401.95
- Arkansas$186.31
- California$255.29
- Colorado$268.68
- Connecticut$277.36
- Delaware$1,124.13
- District of Columbia$284.69
- Florida$343.87
- Georgia$579.89
- Hawaii$368.21
- Idaho$198.58
- Illinois$224.28
- Indiana$299.04
- Iowa$306.24
- Kansas$235.37
- Kentucky$685.51
- Louisiana$138.18
- Maine$189.79
- Maryland$248.69
- Massachusetts$315.59
- Michigan$189.53
- Minnesota$162.50
- Mississippi$183.60
- Montana$168.00
- Nebraska$284.05
- Nevada$147.30
- New Hampshire$324.13
- New Jersey$138.08
- New Mexico$831.56
- New York$241.41
- North Carolina$215.14
- North Dakota$189.54
- Ohio$218.74
- Oklahoma$383.61
- Oregon$173.32
- Rhode Island$270.00
- South Dakota$229.82
- Tennessee$169.86
- Texas$402.20
- Utah$252.28
- Vermont$314.12
- Virginia$176.53
- Washington$189.00
- West Virginia$127.00
- Wisconsin$213.85
Median cash price across the state's hospitals.