Lab tests CPT 81420 Massachusetts Outpatient

NIPT prenatal DNA test cost in Massachusetts

In Massachusetts, 11 hospitals publish a cash price for prenatal cell-free DNA screen for trisomy 21, 18 and 13 (NIPT): from $645.47 to $3,550.00, with a median of $1,685.60. The lowest price is at Boston Medical Center Brighton (Boston). The highest price is 5.5× the lowest.

Outpatient cash prices, one line per hospital — its lowest listed price for code 81420. Prices for both sides of the body and inpatient prices are not mixed in. Collected Sep 23, 2026.

Lowest$645.47Boston Medical Center Brighton
Median$1,685.60half pay less
Highest$3,550.00in Massachusetts
Lowest saves$1,040.13vs the median

Hospitals in Massachusetts, cheapest first

HospitalCash price List priceFile date
Boston Medical Center Brighton lowest Boston · Boston-Cambridge-Newton, MA-NH HC Chg Fetal Chromosomal Aneuploidy Genomic Seq Analys $645.47 $1,434.37 —
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Berkshire Medical Center Pittsfield · Pittsfield, MA Fetal Chrmonl Aneuploidy $1,552.44 $1,634.15 Mar 25, 2026
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Fairview Hospital Great Barrington · Pittsfield, MA Fetal Chrmonl Aneuploidy $1,552.44 $1,634.15 Mar 25, 2026
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North Adams Regional Hospital North Adams · Pittsfield, MA Fetal Chrmonl Aneuploidy $1,552.44 $1,634.15 Mar 25, 2026
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Melrosewakefield Healthcare Melrose · Boston-Cambridge-Newton, MA-NH HC Fetal Chromosomal Aneuploidy Genomic Seq Analys $1,685.60 $2,408.00 —
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Tufts Medical Center Boston · Boston-Cambridge-Newton, MA-NH HC Fetal Chromosomal Aneuploidy Genomic Seq Analys $1,685.60 $2,408.00 —
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Milford Regional Medical Center Milford · Worcester, MA Fetal Chrmoml Aneuploidy $2,047.00 $2,047.00 —
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UMass Memorial Health - Harrington Hospital Southbridge · Worcester, MA HC Qnatal Advanced $2,047.00 $2,047.00 Apr 3, 2026
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HealthAlliance - Clinton Hospital Leominster · Worcester, MA HC Qnatal Advanced $2,931.00 $2,931.00 Mar 26, 2026
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Cambridge Health Alliance Cambridge · Boston-Cambridge-Newton, MA-NH HC Fetal Chromosomal Aneuploidy Genomic Seq Analys So $3,325.00 $3,325.00 —
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UMass Memorial Medical Center Worcester · Worcester, MA HC Qnatal Advanced $3,550.00 $3,550.00 Mar 26, 2026
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By metro area

Each metro page compares every listing, including prices for both sides of the body.

Metro areaHospitals LowestMedian
Boston-Cambridge-Newton, MA-NH 4 $645.47 $1,685.60
Worcester, MA 4 $2,047.00 $2,489.00
Pittsfield, MA 3 $1,552.44 $1,552.44

What it is

NIPT analyzes fragments of fetal DNA that circulate in the mother's blood to screen for Down syndrome (trisomy 21) and trisomies 18 and 13. It can be done from about 10 weeks of pregnancy. It is a screening test, so a positive result needs a diagnostic test to confirm.

What the price covers

The price usually covers the DNA analysis of one blood sample. The blood draw, genetic counseling and any added screens, such as sex chromosomes or microdeletions, may be billed separately.

Prenatal cell-free DNA screen for trisomy 21, 18 and 13 (NIPT) in other states

Median cash price across the state's hospitals.