Lab tests CPT 81420 Pennsylvania Outpatient

NIPT prenatal DNA test cost in Pennsylvania

In Pennsylvania, 32 hospitals publish a cash price for prenatal cell-free DNA screen for trisomy 21, 18 and 13 (NIPT): from $592.28 to $3,787.80, with a median of $2,072.20. The lowest price is at AHN Wexford Hospital (Wexford). The highest price is 6.4× the lowest.

Outpatient cash prices, one line per hospital — its lowest listed price for code 81420. Prices for both sides of the body and inpatient prices are not mixed in. Collected Sep 23, 2026.

Lowest$592.28AHN Wexford Hospital
Median$2,072.20half pay less
Highest$3,787.80in Pennsylvania
Lowest saves$1,479.92vs the median

Hospitals in Pennsylvania, cheapest first

HospitalCash price List priceFile date
AHN Wexford Hospital lowest Wexford · Pittsburgh, PA CHG FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ ANALYS $592.28 $2,278.00 Apr 14, 2026
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Lower Bucks Hospital Bristol · Philadelphia-Camden-Wilmington, PA-NJ-DE-MD Hc Fetal Chrmoml Aneuploidy $759.00 $39.00 Sep 1, 2026
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Roxborough Memorial Hospital Philadelphia · Philadelphia-Camden-Wilmington, PA-NJ-DE-MD Hc Fetal Chrmoml Aneuploidy $759.00 $39.00 Sep 1, 2026
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Bryn Mawr Rehabilitation Hospital Malvern · Philadelphia-Camden-Wilmington, PA-NJ-DE-MD Hc Qnatal Advanced Fetal Chromosomal Aneuploidy Genomic Seq Analys $1,440.80 $3,602.00 —
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Lankenau Medical Center Wynnewood · Philadelphia-Camden-Wilmington, PA-NJ-DE-MD Hc Qnatal Advanced Fetal Chromosomal Aneuploidy Genomic Seq Analys $1,440.80 $3,602.00 Apr 1, 2026
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Paoli Hospital Paoli · Philadelphia-Camden-Wilmington, PA-NJ-DE-MD Hc Qnatal Advanced Fetal Chromosomal Aneuploidy Genomic Seq Analys $1,440.80 $3,602.00 Apr 1, 2026
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Riddle Memorial Hospital Media · Philadelphia-Camden-Wilmington, PA-NJ-DE-MD Hc Qnatal Advanced Fetal Chromosomal Aneuploidy Genomic Seq Analys $1,440.80 $3,602.00 Apr 1, 2026
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The Bryn Mawr Hospital Bryn Mawr · Philadelphia-Camden-Wilmington, PA-NJ-DE-MD Hc Qnatal Advanced Fetal Chromosomal Aneuploidy Genomic Seq Analys $1,440.80 $3,602.00 —
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Penn State Health Milton S. Hershey Medical Center Hershey · Harrisburg-Carlisle, PA QNATAL ADVANCED $1,634.63 $4,934.00 —
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UPMC Carlisle Carlisle · Harrisburg-Carlisle, PA HC QNATAL ADVANCED $1,644.00 $2,740.00 —
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UPMC Hanover Hanover · York-Hanover, PA HC QNATAL ADVANCED $1,644.00 $2,740.00 —
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UPMC Lititz Lititz · Lancaster, PA HC QNATAL ADVANCED $1,644.00 $2,740.00 —
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UPMC Memorial York · York-Hanover, PA HC QNATAL ADVANCED $1,644.00 $2,740.00 —
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UPMC Pinnacle Hospitals Harrisburg · Harrisburg-Carlisle, PA HC QNATAL ADVANCED $1,644.00 $2,740.00 —
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UPMC Somerset Somerset · Somerset, PA HC QNATAL ADVANCED $1,644.00 $2,740.00 —
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Mercy Fitzgerald Hospital Darby · Philadelphia-Camden-Wilmington, PA-NJ-DE-MD HC Quest Analysis Genomic Sequence Fetal Chromosomal Aneuploidy $2,072.20 $3,188.00 Mar 31, 2026
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Nazareth Hospital Philadelphia · Philadelphia-Camden-Wilmington, PA-NJ-DE-MD HC Warde Analysis Genomic Sequence Fetal Chromosomal Aneuploidy $2,072.20 $3,188.00 Mar 31, 2026
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Troy Community Hospital Troy · Sayre, PA Qnatal Advanced $3,320.80 $4,151.00 —
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UPMC Altoona Altoona · Altoona, PA QNATAL ADVANCED $3,388.80 $5,648.00 —
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UPMC Bedford Everett · Everett, PA QNATAL ADVANCED $3,621.60 $6,036.00 —
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UPMC Childrens Hospital of Pittsburgh Pittsburgh · Pittsburgh, PA QNATAL ADVANCED $3,621.60 $6,036.00 Mar 6, 2026
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UPMC Horizon - Greenville Greenville · Hermitage, PA QNATAL ADVANCED $3,621.60 $6,036.00 —
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UPMC Jameson New Castle · Pittsburgh, PA QNATAL ADVANCED $3,621.60 $6,036.00 —
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UPMC Magee-Womens Hospital Pittsburgh · Pittsburgh, PA HC MATERNIT51 PLUS $3,621.60 $6,036.00 —
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UPMC McKeesport McKeesport · Pittsburgh, PA QNATAL ADVANCED $3,621.60 $6,036.00 —
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UPMC Northwest Seneca · Oil City, PA QNATAL ADVANCED $3,621.60 $6,036.00 —
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UPMC Passavant - McCandless Pittsburgh · Pittsburgh, PA HC MATERNIT51 PLUS $3,621.60 $6,036.00 —
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UPMC Presbyterian Pittsburgh · Pittsburgh, PA QNATAL ADVANCED $3,621.60 $6,036.00 Mar 6, 2026
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UPMC St Margaret Pittsburgh · Pittsburgh, PA QNATAL ADVANCED $3,621.60 $6,036.00 —
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Robert Packer Hospital Sayre · Sayre, PA Qnatal Advanced $3,661.20 $4,576.50 —
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Robert Packer Hospital, Towanda Campus Towanda · Sayre, PA Qnatal Advanced $3,661.20 $4,576.50 —
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UPMC Hamot Erie · Erie, PA QNATAL ADVANCED $3,787.80 $6,313.00 —
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By metro area

Each metro page compares every listing, including prices for both sides of the body.

Metro areaHospitals LowestMedian
Philadelphia-Camden-Wilmington, PA-NJ-DE-MD 9 $759.00 $1,440.80
Pittsburgh, PA 8 $592.28 $3,621.60
Harrisburg-Carlisle, PA 3 $1,634.63 $1,644.00
Sayre, PA 3 $3,320.80 $3,661.20
York-Hanover, PA 2 $1,644.00 $1,644.00
Altoona, PA 1 $3,388.80 $3,388.80
Everett, PA 1 $3,621.60 $3,621.60
Erie, PA 1 $3,787.80 $3,787.80
Hermitage, PA 1 $3,621.60 $3,621.60
Lancaster, PA 1 $1,644.00 $1,644.00
Oil City, PA 1 $3,621.60 $3,621.60
Somerset, PA 1 $1,644.00 $1,644.00

What it is

NIPT analyzes fragments of fetal DNA that circulate in the mother's blood to screen for Down syndrome (trisomy 21) and trisomies 18 and 13. It can be done from about 10 weeks of pregnancy. It is a screening test, so a positive result needs a diagnostic test to confirm.

What the price covers

The price usually covers the DNA analysis of one blood sample. The blood draw, genetic counseling and any added screens, such as sex chromosomes or microdeletions, may be billed separately.

Prenatal cell-free DNA screen for trisomy 21, 18 and 13 (NIPT) in other states

Median cash price across the state's hospitals.