Lab tests CPT 81420 Illinois Outpatient

NIPT prenatal DNA test cost in Illinois

In Illinois, 60 hospitals publish a cash price for prenatal cell-free DNA screen for trisomy 21, 18 and 13 (NIPT): from $400.00 to $3,188.00, with a median of $879.90. The lowest price is at Uchicago Medicine AdventHealth Bolingbrook (Bolingbrook) and 3 other hospitals. The highest price is 8.0× the lowest.

  • The median here, $879.90, is 16% below the US median of $1,043.03.
  • That is 1.2× Medicare's 2026 national rate for the same service ($759.05).
  • Illinois ranks 15th of 40 states by median, cheapest first.
  • 13 of 60 hospitals list a cash price equal to their full list price, with no self-pay discount.

Illinois law (Hospital Uninsured Patient Discount Act, 210 ILCS 89): an uninsured Illinois resident with family income up to 600% of the federal poverty level (300% at rural and critical access hospitals) can apply for a discount that brings the bill down to about 135% of the hospital's cost; up to 200% (125% at rural hospitals) medically necessary care is free. A hospital may collect no more than 25% of family income in 12 months. Ask the billing office for the application. Other states' laws.

Outpatient cash prices, one line per hospital — its lowest listed price for code 81420. Prices for both sides of the body and inpatient prices are not mixed in. Collected Nov 9, 2026. See them on a map

Lowest$400.00Uchicago Medicine AdventHealth Bolingbrook + 3 more
Median$879.90half of hospitals charge less
Highest$3,188.00in Illinois
Lowest saves$479.90vs the median

Hospitals in Illinois, cheapest first

HospitalCash priceList priceFile date
Uchicago Medicine AdventHealth Bolingbrook lowest Bolingbrook · Chicago-Naperville-Elgin, IL-IN HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY $400.00 $1,600.00 Apr 1, 2026
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Uchicago Medicine AdventHealth Glenoaks lowest Glendale Heights · Chicago-Naperville-Elgin, IL-IN HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY $400.00 $1,600.00 Apr 1, 2026
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Uchicago Medicine AdventHealth Hinsdale lowest Hinsdale · Chicago-Naperville-Elgin, IL-IN HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY $400.00 $1,600.00 Apr 1, 2026
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Uchicago Medicine AdventHealth La Grange lowest La Grange · Chicago-Naperville-Elgin, IL-IN HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY $400.00 $1,600.00 Apr 1, 2026
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Advocate Childrens Hospital Oak Lawn Oak Lawn · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $477.50 $955.00 Nov 3, 2026
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Advocate Childrens Hospital Park Ridge Park Ridge · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $477.50 $955.00 Nov 6, 2026
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Advocate Christ Medical Center Oak Lawn · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $477.50 $955.00 Nov 3, 2026
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Advocate Condell Medical Center Libertyville · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $477.50 $955.00 Nov 3, 2026
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Advocate Good Samaritan Hospital Downers Grove · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $477.50 $955.00 Nov 3, 2026
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Advocate Good Shepherd Hospital Barrington · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $477.50 $955.00 Nov 3, 2026
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Advocate Illinois Masonic Medical Center Chicago · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $477.50 $955.00 Nov 3, 2026
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Advocate Lutheran General Hospital Park Ridge · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $477.50 $955.00 Nov 3, 2026
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Advocate Sherman Hospital Elgin · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $477.50 $955.00 Nov 3, 2026
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Advocate South Suburban Hospital Hazel Crest · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $477.50 $955.00 Nov 3, 2026
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Advocate Trinity Hospital Chicago · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $477.50 $955.00 Nov 3, 2026
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Riverside Medical Center Kankakee · Kankakee, IL TEST FOR DETECTING GENES ASSOCIATED WITH FETAL DISEASE; ANEUPLOIDY GENOMIC SEQUENCE ANALYSIS PANEL $505.78 $1,900.00 Mar 15, 2026
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Northwestern Medicine McHenry Hospital McHenry · Chicago-Naperville-Elgin, IL-IN HB Ref Maternit21 Plus, Fetal Chromosome Anuploidy (Lc-Z) $562.10 $803.00 Apr 1, 2026
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Touchette Regional Hospital Cahokia Heights · St. Louis, MO-IL Fetal chromosomal aneuploidy (eg, trisomy 21, monosomy X) genomic sequence analysis panel, circulating cell-free fetal DNA in maternal blood, must include analysis of chromosomes 13, 18, and 21 $572.88 $924.00 Apr 13, 2026
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Carlinville Area Hospital Carlinville · St. Louis, MO-IL MATERNIT21 + CORE (CHR. 21 18 13 SEX REF $637.70 $911.00 Mar 21, 2026
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Humboldt Park Health Chicago · Chicago-Naperville-Elgin, IL-IN Test for detecting genes associated with fetal disease, aneuploidy genomic sequence analysis panel $669.44 $2,390.85 Sep 29, 2026
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Trinity Rock Island Rock Island · Davenport-Moline-Rock Island, IA-IL HC FETAL CHROMOSOMAL ANEUPLOIDY $728.69 $910.86 Nov 4, 2026
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MercyOne Genesis Aledo Medical Center Aledo · Davenport-Moline-Rock Island, IA-IL informaSeq Prenatal Test-Sendout $729.60 $1,216.00 Mar 31, 2026
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Mercy Medical Center Aurora · Chicago-Naperville-Elgin, IL-IN FETAL CHRMOML ANEUPLOIDY $759.00 $2,180.00 Sep 1, 2026
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Saint Joseph Medical Center - Joliet Joliet · Chicago-Naperville-Elgin, IL-IN FETAL CHRMOML ANEUPLOIDY - 81420 - 30015170 $759.00 $5,184.00 Sep 1, 2026
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Presence Saint Joseph Hospital - Chicago Chicago · Chicago-Naperville-Elgin, IL-IN HC FETAL CHROMOSOMAL ANEUPLOIDY $770.55 $2,335.00 Jan 1, 2026
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Palos Community Hospital Palos Heights · Chicago-Naperville-Elgin, IL-IN HB Ref Qnataltm Advanced, Fetal Chromosomal Aneuploidy (Q-Z) $800.10 $1,143.00 Apr 1, 2026
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Louis A Weiss Memorial Hospital Chicago · Chicago-Naperville-Elgin, IL-IN MaterniT21 PLUS Core+SCA SO $805.42 $2,368.88 Mar 17, 2025
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Resilience Healthcare West Suburban Medical Center Oak Park · Chicago-Naperville-Elgin, IL-IN MaterniT21 PLUS Core+SCA SO $805.42 $2,368.88 Mar 17, 2025
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Northwestern Lake Forest Hospital Lake Forest · Chicago-Naperville-Elgin, IL-IN HB Ref Maternit21 Plus Core (Lc-Z) $879.90 $1,257.00 Apr 1, 2026
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Northwestern Medicine Central DuPage Hospital Winfield · Chicago-Naperville-Elgin, IL-IN HB Ref Qnataltm Advanced, Fetal Chromosomal Aneuploidy (Q-Z) $879.90 $1,257.00 Apr 1, 2026
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Northwestern Medicine Delnor Hospital Geneva · Chicago-Naperville-Elgin, IL-IN HB Ref Maternit Genome, Fetal Chromosomal Aneuploidy (Lc-Z) $879.90 $1,257.00 Apr 1, 2026
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Northwestern Medicine Kishwaukee Hospital DeKalb · Chicago-Naperville-Elgin, IL-IN HB Ref Maternit Genome, Fetal Chromosomal Aneuploidy (Lc-Z) $879.90 $1,257.00 Apr 1, 2026
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Northwestern Medicine Valley West Hospital Sandwich · Chicago-Naperville-Elgin, IL-IN HB Ref Maternit Genome, Fetal Chromosomal Aneuploidy (Lc-Z) $879.90 $1,257.00 Apr 1, 2026
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Northwestern Memorial Hospital Chicago · Chicago-Naperville-Elgin, IL-IN HB Ref Qnataltm Advanced, Fetal Chromosomal Aneuploidy (Q-Z) $879.90 $1,257.00 Apr 1, 2026
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Vista Medical Center East Waukegan · Chicago-Naperville-Elgin, IL-IN FET ANEUP GSA PN $936.23 $936.23 Mar 31, 2025
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Gateway Regional Medical Center Granite City · St. Louis, MO-IL 451934 MTNLT21 CRSCA $1,050.00 $1,750.00 Mar 30, 2026
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Ingalls Memorial Hospital Harvey · Chicago-Naperville-Elgin, IL-IN Noncdm Charge Record $1,258.00 $1,258.00 Apr 1, 2026
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John H. Stroger, Jr. Hospital Chicago · Chicago-Naperville-Elgin, IL-IN RL-QNATAL ADVANCE $1,328.60 $1,898.00 Apr 1, 2026
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Northwest Community Hospital Arlington Heights · Chicago-Naperville-Elgin, IL-IN Hb Fetal Chrmoml Aneuploidy $1,380.00 $1,380.00 Apr 1, 2026
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Harrisburg Medical Center Harrisburg · Harrisburg, IL HC Nipt for Fetal Aneuploidy $1,497.60 $1,872.00 Mar 4, 2026
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Herrin Hospital Herrin · Marion-Herrin, IL HC Nipt for Fetal Aneuploidy $1,497.60 $1,872.00 Mar 4, 2026
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Memorial Hospital of Carbondale Carbondale · Carbondale, IL HC Nipt for Fetal Aneuploidy $1,497.60 $1,872.00 Mar 4, 2026
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St Joseph Memorial Hospital Murphysboro · Carbondale, IL HC Nipt for Fetal Aneuploidy $1,497.60 $1,872.00 Mar 4, 2026
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Anderson Hospital Maryville · St. Louis, MO-IL FETAL CHRMOML ANEUPLOIDY $1,761.15 $3,522.30 Feb 6, 2026
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Community Hospital of Staunton Staunton · St. Louis, MO-IL FETAL CHRMOML ANEUPLOIDY $1,761.15 $3,522.30 Feb 9, 2026
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Gibson Area Hospital Gibson City · Champaign-Urbana, IL MATERNIT21 PLUS CORE W/ GENDER $2,006.00 $2,006.00 Nov 4, 2026
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MercyOne Genesis Silvis Medical Center Silvis · Davenport-Moline-Rock Island, IA-IL informaSeq(SM)with XY Analysis - Sendout $2,027.40 $3,379.00 Mar 31, 2026
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Fairfield Memorial Hospital Fairfield · Fairfield, IL MATERNITY T21 QNATAL $2,232.80 $2,791.00 Mar 24, 2026
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Carle BroMenn Medical Center Normal · Bloomington, IL Maternit21 Ref $2,277.00 $2,277.00 Apr 15, 2026
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Mercyhealth Crystal Lake Hospital & Medical Center Crystal Lake · Chicago-Naperville-Elgin, IL-IN CHG FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ ANALYS $2,507.08 $3,342.78 Mar 1, 2026
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Rockford Memorial Hospital Rockford · Rockford, IL CHG FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ ANALYS $2,558.67 $3,411.56 Mar 1, 2026
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Pinckneyville Community Hospital Pinckneyville · Pinckneyville, IL Test for detecting genes associated with fetal disease, aneuploidy genomic sequence analysis panel $2,570.00 $2,570.00 Jun 8, 2026
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Richland Memorial Hospital Olney · Olney, IL Qnatal(Tm) Advanced $2,860.00 $2,860.00 Apr 15, 2026
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Carle Eureka Hospital Eureka · Peoria, IL Maternit21 Ref $3,036.00 $3,036.00 Apr 15, 2026
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Carle Health Pekin Hospital Pekin · Peoria, IL Arup Non-Invasive Prenatal Aneuploidy by Ngs $3,036.00 $3,036.00 Apr 15, 2026
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Methodist Medical Center of Illinois Peoria · Peoria, IL Arup Non-Invasive Prenatal Aneuploidy by Ngs $3,036.00 $3,036.00 Apr 15, 2026
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Proctor Community Hospital Peoria · Peoria, IL Arup Non-Invasive Prenatal Aneuploidy by Ngs $3,036.00 $3,036.00 Apr 15, 2026
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Hardin County General Hospital Rosiclare · Rosiclare, IL NIPT FOR FETAL ANEUPLOIDY $3,048.30 $3,387.00 Aug 31, 2026
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Hoopeston Community Memorial Hospital Hoopeston · Danville, IL Arup Non-Invasive Prenatal Aneuploidy by Ngs $3,180.00 $3,180.00 Apr 15, 2026
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The Carle Foundation Hospital Urbana · Champaign-Urbana, IL Maternit21 Ref $3,188.00 $3,188.00 Apr 15, 2026
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Hospital The hospital that published the price, its city and the line exactly as written in its price file.
Cash price The hospital's own price for a patient paying without insurance (“discounted cash” in its price file). Hospitals must publish it under federal law, 45 CFR 180.50. Call to confirm it before booking. More
List price The hospital's full chargemaster price (“gross charge”) before any discount. Almost nobody pays it; the gap to the cash price shows what the self-pay discount is worth. More
File date When the hospital last updated its price file, as the file says itself. A dash means the file gives no date.
No cash discount This line's cash price equals the hospital's full list price. Many hospitals still reduce bills for uninsured patients: ask the billing office for its self-pay discount in writing. More

By metro area

Each metro page compares every listing, including prices for both sides of the body.

Metro areaHospitalsLowestMedian
Chicago-Naperville-Elgin, IL-IN 34 $400.00 $714.22
St. Louis, MO-IL 5 $572.88 $1,050.00
Peoria, IL 4 $3,036.00 $3,036.00
Davenport-Moline-Rock Island, IA-IL 3 $728.69 $729.60
Carbondale, IL 2 $1,497.60 $1,497.60
Champaign-Urbana, IL 2 $2,006.00 $2,597.00
Bloomington, IL 1 $2,277.00 $2,277.00
Danville, IL 1 $3,180.00 $3,180.00
Fairfield, IL 1 $2,232.80 $2,232.80
Harrisburg, IL 1 $1,497.60 $1,497.60
Kankakee, IL 1 $505.78 $505.78
Marion-Herrin, IL 1 $1,497.60 $1,497.60
Olney, IL 1 $2,860.00 $2,860.00
Pinckneyville, IL 1 $2,570.00 $2,570.00
Rosiclare, IL 1 $3,048.30 $3,048.30
Rockford, IL 1 $2,558.67 $2,558.67
Market A metro area (as the Census Bureau defines it) or, outside metro areas, a town. Each links to every hospital price there.
Hospitals How many hospitals publish a cash price for this code here. Each hospital counts once, at its lowest outpatient cash price.
Lowest The lowest cash price among those hospitals.
Median The middle cash price: half of the hospitals charge less, half charge more. One price per hospital. More

What NIPT prenatal DNA test is, what the price covers and why prices differ: NIPT prenatal DNA test explained.

Prenatal cell-free DNA screen for trisomy 21, 18 and 13 (NIPT) in other states

Median cash price across the state's hospitals.