Lab tests CPT 81420 Illinois Outpatient

NIPT prenatal DNA test cost in Illinois

In Illinois, 35 hospitals publish a cash price for prenatal cell-free DNA screen for trisomy 21, 18 and 13 (NIPT): from $400.00 to $2,027.40, with a median of $669.44. The lowest price is at Uchicago Medicine AdventHealth Bolingbrook (Bolingbrook) and 3 other hospitals. The highest price is 5.1× the lowest.

Outpatient cash prices, one line per hospital — its lowest listed price for code 81420. Prices for both sides of the body and inpatient prices are not mixed in. Collected Sep 23, 2026.

Lowest$400.00Uchicago Medicine AdventHealth Bolingbrook + 3 more
Median$669.44half pay less
Highest$2,027.40in Illinois
Lowest saves$269.44vs the median

Hospitals in Illinois, cheapest first

HospitalCash price List priceFile date
Uchicago Medicine AdventHealth Bolingbrook lowest Bolingbrook · Chicago-Naperville-Elgin, IL-IN HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY $400.00 $1,600.00 Apr 1, 2026
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Uchicago Medicine AdventHealth Glenoaks lowest Glendale Heights · Chicago-Naperville-Elgin, IL-IN HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY $400.00 $1,600.00 Apr 1, 2026
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Uchicago Medicine AdventHealth Hinsdale lowest Hinsdale · Chicago-Naperville-Elgin, IL-IN HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY $400.00 $1,600.00 Apr 1, 2026
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Uchicago Medicine AdventHealth La Grange lowest La Grange · Chicago-Naperville-Elgin, IL-IN HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY $400.00 $1,600.00 Apr 1, 2026
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Advocate Childrens Hospital Oak Lawn Oak Lawn · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $462.50 $925.00 Nov 4, 2025
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Advocate Childrens Hospital Park Ridge Park Ridge · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $462.50 $925.00 Nov 4, 2025
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Advocate Christ Medical Center Oak Lawn · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $462.50 $925.00 Nov 4, 2025
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Advocate Condell Medical Center Libertyville · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $462.50 $925.00 Nov 4, 2025
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Advocate Good Samaritan Hospital Downers Grove · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $462.50 $925.00 Nov 4, 2025
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Advocate Good Shepherd Hospital Barrington · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $462.50 $925.00 Nov 4, 2025
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Advocate Illinois Masonic Medical Center Chicago · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $462.50 $925.00 Nov 4, 2025
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Advocate Lutheran General Hospital Park Ridge · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $462.50 $925.00 Nov 4, 2025
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Advocate Sherman Hospital Elgin · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $462.50 $925.00 Nov 4, 2025
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Advocate South Suburban Hospital Hazel Crest · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $462.50 $925.00 Nov 4, 2025
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Advocate Trinity Hospital Chicago · Chicago-Naperville-Elgin, IL-IN FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ $462.50 $925.00 Nov 4, 2025
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Riverside Medical Center Kankakee · Kankakee, IL TEST FOR DETECTING GENES ASSOCIATED WITH FETAL DISEASE; ANEUPLOIDY GENOMIC SEQUENCE ANALYSIS PANEL $505.78 $1,900.00 —
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Northwestern Medicine McHenry Hospital McHenry · Chicago-Naperville-Elgin, IL-IN HB Ref Maternit21 Plus, Fetal Chromosome Anuploidy (Lc-Z) $562.10 $803.00 Apr 1, 2026
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Humboldt Park Health Chicago · Chicago-Naperville-Elgin, IL-IN Test for detecting genes associated with fetal disease, aneuploidy genomic sequence analysis panel $669.44 $2,390.85 Aug 24, 2026
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Trinity Medical Center Rock Island · Davenport-Moline-Rock Island, IA-IL HC FETAL CHROMOSOMAL ANEUPLOIDY $728.69 $910.86 Jan 28, 2026
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MercyOne Genesis Aledo Medical Center Aledo · Davenport-Moline-Rock Island, IA-IL informaSeq Prenatal Test-Sendout $729.60 $1,216.00 Mar 31, 2026
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Mercy Medical Center Aurora · Chicago-Naperville-Elgin, IL-IN FETAL CHRMOML ANEUPLOIDY $759.00 $2,180.00 Sep 1, 2026
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Presence Saint Joseph Hospital - Chicago Chicago · Chicago-Naperville-Elgin, IL-IN HC FETAL CHROMOSOMAL ANEUPLOIDY $770.55 $2,335.00 —
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Palos Community Hospital Palos Heights · Chicago-Naperville-Elgin, IL-IN HB Ref Qnataltm Advanced, Fetal Chromosomal Aneuploidy (Q-Z) $800.10 $1,143.00 Apr 1, 2026
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Louis A Weiss Memorial Hospital Chicago · Chicago-Naperville-Elgin, IL-IN MaterniT21 PLUS Core+SCA SO $805.42 $2,368.88 Mar 17, 2025
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Resilience Healthcare West Suburban Medical Center Oak Park · Chicago-Naperville-Elgin, IL-IN MaterniT21 PLUS Core+SCA SO $805.42 $2,368.88 Mar 17, 2025
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Northwestern Lake Forest Hospital Lake Forest · Chicago-Naperville-Elgin, IL-IN HB Ref Maternit Genome, Fetal Chromosomal Aneuploidy (Lc-Z) $879.90 $1,257.00 Apr 1, 2026
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Northwestern Medicine Central DuPage Hospital Winfield · Chicago-Naperville-Elgin, IL-IN HB Ref Maternit21 Plus Core + Ess + Sca, Fetal Chrmoml Aneuploidy (Lc-Z) $879.90 $1,257.00 Apr 1, 2026
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Northwestern Medicine Delnor Hospital Geneva · Chicago-Naperville-Elgin, IL-IN HB Ref Maternit21 Plus Core + Sca (Lc-Z) $879.90 $1,257.00 Apr 1, 2026
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Northwestern Medicine Kishwaukee Hospital DeKalb · Chicago-Naperville-Elgin, IL-IN HB Ref Maternit Genome, Fetal Chromosomal Aneuploidy (Lc-Z) $879.90 $1,257.00 Apr 1, 2026
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Northwestern Medicine Marianjoy Rehabilitation Hospital Wheaton · Chicago-Naperville-Elgin, IL-IN HB Ref Maternit21 Plus Core (Lc-Z) $879.90 $1,257.00 Apr 1, 2026
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Northwestern Medicine Valley West Hospital Sandwich · Chicago-Naperville-Elgin, IL-IN HB Ref Maternit Genome, Fetal Chromosomal Aneuploidy (Lc-Z) $879.90 $1,257.00 Apr 1, 2026
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Gateway Regional Medical Center Granite City · St. Louis, MO-IL 451934 MTNLT21 CRSCA $1,050.00 $1,750.00 —
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Ingalls Memorial Hospital Harvey · Chicago-Naperville-Elgin, IL-IN Hc Fetal Chromosomal Aneuploidy Genomic Seq Analys $1,258.00 $1,258.00 Apr 1, 2026
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Northwest Community Hospital Arlington Heights · Chicago-Naperville-Elgin, IL-IN Hb Fetal Chrmoml Aneuploidy $1,380.00 $1,380.00 Apr 1, 2026
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MercyOne Genesis Silvis Medical Center Silvis · Davenport-Moline-Rock Island, IA-IL informaSeq Prenatal Test-Sendout $2,027.40 $3,379.00 Mar 31, 2026
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By metro area

Each metro page compares every listing, including prices for both sides of the body.

Metro areaHospitals LowestMedian
Chicago-Naperville-Elgin, IL-IN 30 $400.00 $512.30
Davenport-Moline-Rock Island, IA-IL 3 $728.69 $729.60
Kankakee, IL 1 $505.78 $505.78
St. Louis, MO-IL 1 $1,050.00 $1,050.00

What it is

NIPT analyzes fragments of fetal DNA that circulate in the mother's blood to screen for Down syndrome (trisomy 21) and trisomies 18 and 13. It can be done from about 10 weeks of pregnancy. It is a screening test, so a positive result needs a diagnostic test to confirm.

What the price covers

The price usually covers the DNA analysis of one blood sample. The blood draw, genetic counseling and any added screens, such as sex chromosomes or microdeletions, may be billed separately.

Prenatal cell-free DNA screen for trisomy 21, 18 and 13 (NIPT) in other states

Median cash price across the state's hospitals.