NIPT prenatal DNA test cost in Boston, MA
In Boston-Cambridge-Newton, MA-NH, 14 hospitals list a cash price for prenatal cell-free DNA screen for trisomy 21, 18 and 13 (NIPT): from $645.47 to $3,698.00, with a median of $2,712.50. The lowest listed price is at Boston Medical Center Brighton — $2,067.03 less than the median here. Across Massachusetts, the median is $2,583.00 at 21 hospitals.
- The median here, $2,712.50, is 160% above the US median of $1,043.03.
- That is 3.6× Medicare's 2026 national rate for the same service ($759.05).
- 10 of 14 hospitals list a cash price equal to their full list price, with no self-pay discount.
Cash prices at 14 facilities across 10 cities for code 81420, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 27, 2026; the hospital files themselves were last updated between Jan 28, 2026 and Apr 1, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Boston-Cambridge-Newton, MA-NH.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list |
|---|---|---|---|---|
| Boston Medical Center Brighton lowest Boston, MA · (617) 789-3000 HC Chg Fetal Chromosomal Aneuploidy Genomic Seq Analys File of Mar 13, 2026 · source file | $645.47 | $1,434.37 | $475.07–$2,305.51 | 55% |
| Anna Jaques Hospital Newburyport, MA · (978) 463-1000 CHG FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ ANALYS File of Apr 1, 2026 · source file | $1,622.00 | $1,622.00 | — | — |
| Melrosewakefield Healthcare Melrose, MA · (781) 979-3000 HC Fetal Chromosomal Aneuploidy Genomic Seq Analys File of Apr 1, 2026 · source file | $1,685.60 | $2,408.00 | $76.00–$2,633.90 | 30% |
| Tufts Medical Center Boston, MA · (617) 636-5000 HC Fetal Chromosomal Aneuploidy Genomic Seq Analys File of Apr 1, 2026 · source file | $1,685.60 | $2,408.00 | $632.34–$3,293.84 | 30% |
| Signature Healthcare Brockton Hospital Brockton, MA · (508) 941-7000 QNatal File of Jan 28, 2026 · source file | $2,163.00 | $3,090.00 | $683.15–$1,871.79 | 30% |
| Beth Israel Deaconess Hospital - Plymouth Plymouth, MA · (508) 746-2000 CHG FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ ANALYS File of Apr 1, 2026 · source file | $2,583.00 | $2,583.00 | — | — |
| Beth Israel Deaconess Hospital-Milton Milton, MA · (617) 696-4600 CHG FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ ANALYS File of Apr 1, 2026 · source file | $2,672.00 | $2,672.00 | — | — |
| Lahey Hospital & Medical Center, Burlington Burlington, MA · (781) 744-5100 CHG FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ ANALYS File of Apr 1, 2026 · source file | $2,753.00 | $2,753.00 | — | — |
| New England Baptist Hospital Boston, MA · (617) 754-5800 CHG FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ ANALYS File of Apr 1, 2026 · source file | $2,818.00 | $2,818.00 | — | — |
| Mount Auburn Hospital Cambridge, MA · (617) 492-3500 CHG FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ ANALYS File of Apr 1, 2026 · source file | $2,860.00 | $2,860.00 | — | — |
| Winchester Hospital Winchester, MA · (781) 729-9000 CHG FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ ANALYS File of Apr 1, 2026 · source file | $2,968.00 | $2,968.00 | — | — |
| Beth Israel Deaconess Medical Center Boston, MA · (617) 667-7000 CHG FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ ANALYS File of Apr 1, 2026 · source file | $3,321.00 | $3,321.00 | — | — |
| Cambridge Health Alliance Cambridge, MA · (617) 665-1000 HC Fetal Chromosomal Aneuploidy Genomic Seq Analys So File of Mar 20, 2026 · source file | $3,325.00 | $3,325.00 | $560.83–$3,325.00 | — |
| Beth Israel Deaconess Hospital - Needham Needham, MA · (781) 453-3002 CHG FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ ANALYS File of Apr 1, 2026 · source file | $3,698.00 | $3,698.00 | — | — |
Outpatient: lowest $645.47, median $2,712.50, highest $3,698.00 — a 5.7× difference within the same market.
As an inpatient, the same code is billed by 14 facilities here, median $2,712.50. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 3 of 5 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What NIPT prenatal DNA test is, what the price covers and why prices differ: NIPT prenatal DNA test explained.