NIPT prenatal DNA test cost in Chicago, IL
In Chicago-Naperville-Elgin, IL-IN, 40 hospitals list a cash price for prenatal cell-free DNA screen for trisomy 21, 18 and 13 (NIPT): from $400.00 to $2,507.08, with a median of $714.71. The lowest listed price is at Uchicago Medicine AdventHealth La Grange and 3 other hospitals — $314.71 less than the median here. Across Illinois, the median is $879.90 at 60 hospitals.
- The median here, $714.71, is 31% below the US median of $1,043.03.
- That is 0.9× Medicare's 2026 national rate for the same service ($759.05).
- 3 of 40 hospitals list a cash price equal to their full list price, with no self-pay discount.
Cash prices at 40 facilities across 32 cities for code 81420, as an outpatient — the setting a self-pay patient normally buys. Collected Nov 9, 2026; the hospital files themselves were last updated between Mar 17, 2025 and Nov 6, 2026.
Lowest$400.00Uchicago Medicine AdventHealth La Grange + 3 more
Median$714.71half of hospitals charge less
Highest$2,507.08in this market
Difference6.3×highest vs lowest
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Chicago-Naperville-Elgin, IL-IN.
median
Lowest $400.00Highest $2,527.70
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list |
|---|---|---|---|---|
| Uchicago Medicine AdventHealth La Grange lowest La Grange, IL · (708) 352-1200 HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY File of Apr 1, 2026 · source file | $400.00 | $1,600.00 | — | 75% |
| Uchicago Medicine AdventHealth Glenoaks lowest Glendale Heights, IL · (630) 545-8000 HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY File of Apr 1, 2026 · source file | $400.00 | $1,600.00 | — | 75% |
| Uchicago Medicine AdventHealth Hinsdale lowest Hinsdale, IL · (630) 856-9000 HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY File of Apr 1, 2026 · source file | $400.00 | $1,600.00 | — | 75% |
| Uchicago Medicine AdventHealth Bolingbrook lowest Bolingbrook, IL · (630) 312-5000 HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY File of Apr 1, 2026 · source file | $400.00 | $1,600.00 | — | 75% |
| Advocate Childrens Hospital Park Ridge Park Ridge, IL FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ File of Nov 6, 2026 · source file | $477.50 | $955.00 | $376.27–$3,494.85 | 50% |
| Advocate Good Samaritan Hospital Downers Grove, IL · (630) 275-5900 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ File of Nov 3, 2026 · source file | $477.50 | $955.00 | $376.27–$3,494.85 | 50% |
| Advocate Good Shepherd Hospital Barrington, IL · (847) 381-9600 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ File of Nov 3, 2026 · source file | $477.50 | $955.00 | $376.27–$3,494.85 | 50% |
| Advocate Christ Medical Center Oak Lawn, IL · (708) 684-8000 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ File of Nov 3, 2026 · source file | $477.50 | $955.00 | $376.27–$3,494.85 | 50% |
| Advocate Illinois Masonic Medical Center Chicago, IL · (773) 975-1600 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ File of Nov 3, 2026 · source file | $477.50 | $955.00 | $376.27–$3,494.85 | 50% |
| Advocate Childrens Hospital Oak Lawn Oak Lawn, IL FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ File of Nov 3, 2026 · source file | $477.50 | $955.00 | $376.27–$3,494.85 | 50% |
| Advocate Sherman Hospital Elgin, IL · (847) 742-9800 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ File of Nov 3, 2026 · source file | $477.50 | $955.00 | $292.23–$3,494.85 | 50% |
| Advocate Trinity Hospital Chicago, IL · (773) 967-5002 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ File of Nov 3, 2026 · source file | $477.50 | $955.00 | $376.27–$3,494.85 | 50% |
| Advocate Lutheran General Hospital Park Ridge, IL · (847) 723-2210 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ File of Nov 3, 2026 · source file | $477.50 | $955.00 | $376.27–$3,494.85 | 50% |
| Advocate Condell Medical Center Libertyville, IL · (847) 362-2900 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ File of Nov 3, 2026 · source file | $477.50 | $955.00 | $376.27–$3,494.85 | 50% |
| Advocate South Suburban Hospital Hazel Crest, IL FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ File of Nov 3, 2026 · source file | $477.50 | $955.00 | $376.27–$3,494.85 | 50% |
| Franciscan Health Munster Munster, IN · (219) 922-4200 Fetal Chrmoml Aneuploidy File of Jan 1, 2026 · source file | $528.88 | $2,483.00 | $126.00–$3,415.73 | 79% |
| Northwestern Medicine McHenry Hospital McHenry, IL · (815) 344-5000 HB Ref Maternit21 Plus Core + Ess + Sca, Fetal Chrmoml Aneuploidy (Lc-Z)+1 more line at this price File of Apr 1, 2026 · source file | $562.10 | $803.00 | $154.98–$803.00 | 30% |
| Franciscan Health Crown Point Crown Point, IN · (219) 757-6100 Fetal Chrmoml Aneuploidy File of Jan 1, 2026 · source file | $640.61 | $2,483.00 | $2,483.00 | 74% |
| Humboldt Park Health Chicago, IL · (773) 292-8200 Test for detecting genes associated with fetal disease, aneuploidy genomic sequence analysis panel File of Sep 29, 2026 · source file | $669.44 | $2,390.85 | $788.98–$2,510.39 | 72% |
| Franciscan Health Dyer Dyer, IN · (219) 865-2141 Fetal Chrmoml Aneuploidy File of Jan 1, 2026 · source file | $670.41 | $2,483.00 | $126.00–$2,277.15 | 73% |
| Saint Joseph Medical Center - Joliet Joliet, IL · (815) 725-7133 FETAL CHRMOML ANEUPLOIDY - 81420 - 31001745+2 more lines at this price File of Sep 1, 2026 · source file | $759.00 | $1,037.00 | $156.27–$5,184.00 | 27% |
| Mercy Medical Center Aurora, IL · (630) 859-2222 NIPT FETAL ANEUPLOIDY+1 more line at this price File of Sep 1, 2026 · source file | $759.00 | $2,180.00 | $436.00–$2,180.00 | 65% |
| Presence Saint Joseph Hospital - Chicago Chicago, IL · (773) 665-3000 HC FETAL CHROMOSOMAL ANEUPLOIDY+1 more line at this price File of Jan 1, 2026 · source file | $770.55 | $2,335.00 | $759.05–$1,100.62 | 67% |
| Palos Community Hospital Palos Heights, IL · (708) 923-4000 HB Ref Qnataltm Advanced, Fetal Chromosomal Aneuploidy (Q-Z) File of Apr 1, 2026 · source file | $800.10 | $1,143.00 | $182.88–$1,143.00 | 30% |
| Louis A Weiss Memorial Hospital Chicago, IL · (773) 878-8700 MaterniT21 PLUS Core+SCA SO File of Mar 17, 2025 · source file | $805.42 | $2,368.88 | $393.94–$1,539.77 | 66% |
| Resilience Healthcare West Suburban Medical Center Oak Park, IL · (708) 383-6200 MaterniT21 PLUS Core+SCA SO File of Mar 17, 2025 · source file | $805.42 | $2,368.88 | $351.54–$1,539.77 | 66% |
| Methodist Hospital-Southlake Merrillville, IN · (219) 886-4000 HC Fetal Chromosomal Aneuploidy Genomic Sequence Analysis Panel+2 more lines at this price File of Aug 18, 2026 · source file | $835.10 | $1,193.00 | $458.11–$2,003.90 | 30% |
| The Methodist Hospitals Gary, IN · (219) 886-4000 HC Maternit 21 Plus Core + Sca (Mt21s)+2 more lines at this price File of Aug 18, 2026 · source file | $835.10 | $1,193.00 | $458.11–$2,003.90 | 30% |
| Northwestern Medicine Kishwaukee Hospital DeKalb, IL · (815) 756-1521 HB Ref Maternit21 Plus Core (Lc-Z)+1 more line at this price File of Apr 1, 2026 · source file | $879.90 | $1,257.00 | $230.03–$1,257.00 | 30% |
| Palos Community Hospital Palos Heights, IL · (708) 923-4000 HB Ref Maternit Genome, Fetal Chromosomal Aneuploidy (Lc-Z)+1 more line at this price File of Apr 1, 2026 · source file | $879.90 | $1,257.00 | $201.12–$1,257.00 | 30% |
| Northwestern Medicine Central DuPage Hospital Winfield, IL · (630) 682-1600 HB Ref Maternit21 Plus, Fetal Chromosome Anuploidy (Lc-Z)+5 more lines at this price File of Apr 1, 2026 · source file | $879.90 | $1,257.00 | $86.73–$1,257.00 | 30% |
| Northwestern Medicine McHenry Hospital McHenry, IL · (815) 344-5000 HB Ref Maternit Genome, Fetal Chromosomal Aneuploidy (Lc-Z)+1 more line at this price File of Apr 1, 2026 · source file | $879.90 | $1,257.00 | $242.60–$1,257.00 | 30% |
| Northwestern Medicine Valley West Hospital Sandwich, IL · (815) 786-8484 HB Ref Maternit Genome, Fetal Chromosomal Aneuploidy (Lc-Z)+1 more line at this price File of Apr 1, 2026 · source file | $879.90 | $1,257.00 | $238.83–$1,257.00 | 30% |
| Northwestern Memorial Hospital Chicago, IL · (312) 926-2000 HB Ref Maternit21 Plus, Fetal Chromosome Anuploidy (Lc-Z)+5 more lines at this price File of Apr 1, 2026 · source file | $879.90 | $1,257.00 | $216.81–$2,183.00 | 30% |
| Northwestern Medicine Delnor Hospital Geneva, IL · (630) 208-3000 HB Ref Maternit21 Plus, Fetal Chromosome Anuploidy (Lc-Z)+5 more lines at this price File of Apr 1, 2026 · source file | $879.90 | $1,257.00 | $187.29–$1,257.00 | 30% |
| Northwestern Lake Forest Hospital Lake Forest, IL · (847) 234-5600 HB Ref Maternit Genome, Fetal Chromosomal Aneuploidy (Lc-Z)+1 more line at this price File of Apr 1, 2026 · source file | $879.90 | $1,257.00 | $208.66–$1,257.00 | 30% |
| Northwestern Medicine Valley West Hospital Sandwich, IL · (815) 786-8484 HB Ref Prequel Prenatal Screen (Myriad) File of Apr 1, 2026 · source file | $926.80 | $1,324.00 | $251.56–$1,324.00 | 30% |
| Northwestern Medicine McHenry Hospital McHenry, IL · (815) 344-5000 HB Ref Prequel Prenatal Screen (Myriad) File of Apr 1, 2026 · source file | $926.80 | $1,324.00 | $255.53–$1,324.00 | 30% |
| Northwestern Memorial Hospital Chicago, IL · (312) 926-2000 HB Ref Prequel Prenatal Screen (Myriad) File of Apr 1, 2026 · source file | $926.80 | $1,324.00 | $256.86–$1,324.00 | 30% |
| Northwestern Medicine Kishwaukee Hospital DeKalb, IL · (815) 756-1521 HB Ref Prequel Prenatal Screen (Myriad) File of Apr 1, 2026 · source file | $926.80 | $1,324.00 | $242.29–$1,324.00 | 30% |
| Northwestern Lake Forest Hospital Lake Forest, IL · (847) 234-5600 HB Ref Prequel Prenatal Screen (Myriad) File of Apr 1, 2026 · source file | $926.80 | $1,324.00 | $219.78–$1,324.00 | 30% |
| Northwestern Medicine Delnor Hospital Geneva, IL · (630) 208-3000 HB Ref Prequel Prenatal Screen (Myriad) File of Apr 1, 2026 · source file | $926.80 | $1,324.00 | $197.28–$1,324.00 | 30% |
| Palos Community Hospital Palos Heights, IL · (708) 923-4000 HB Ref Prequel Prenatal Screen (Myriad) File of Apr 1, 2026 · source file | $926.80 | $1,324.00 | $211.84–$1,324.00 | 30% |
| Northwestern Medicine Central DuPage Hospital Winfield, IL · (630) 682-1600 HB Ref Prequel Prenatal Screen (Myriad) File of Apr 1, 2026 · source file | $926.80 | $1,324.00 | $91.36–$1,324.00 | 30% |
| Vista Medical Center East Waukegan, IL · (847) 360-3000 FET ANEUP GSA PN File of Mar 31, 2025 · source file | $936.23 | $936.23 | $56.17–$1,222.07 | — |
| Franciscan Health Rensselaer Rensselaer, IN · (219) 866-5141 Fetal Chrmoml Aneuploidy File of Jan 1, 2026 · source file | $995.24 | $2,780.00 | $679.35–$3,415.73 | 64% |
| Northwestern Medicine McHenry Hospital McHenry, IL · (815) 344-5000 HB Ref Maternit21 Plus Core + Sca (Lc-Z) File of Apr 1, 2026 · source file | $1,124.20 | $1,606.00 | $309.96–$1,606.00 | 30% |
| Ingalls Memorial Hospital Harvey, IL · (708) 333-2300 Noncdm Charge Record+1 more line at this price File of Apr 1, 2026 · source file | $1,258.00 | $1,258.00 | — | — |
| John H. Stroger, Jr. Hospital Chicago, IL · (312) 864-6000 RL-QNATAL ADVANCE File of Apr 1, 2026 · source file | $1,328.60 | $1,898.00 | $137.00–$1,518.40 | 30% |
| Northwest Community Hospital Arlington Heights, IL · (847) 618-1000 Hb Fetal Chrmoml Aneuploidy File of Apr 1, 2026 · source file | $1,380.00 | $1,380.00 | — | — |
| The Methodist Hospitals Gary, IN · (219) 886-4000 HC Maternit 21 Plus Core, No Gender (Mt21ng) File of Aug 18, 2026 · source file | $1,475.60 | $2,108.00 | $759.05–$2,003.90 | 30% |
| Methodist Hospital-Southlake Merrillville, IN · (219) 886-4000 HC Maternit 21 Plus Core, No Gender (Mt21ng) File of Aug 18, 2026 · source file | $1,475.60 | $2,108.00 | $759.05–$2,003.90 | 30% |
| Northwestern Medicine McHenry Hospital McHenry, IL · (815) 344-5000 HB Ref Qnataltm Advanced, Fetal Chromosomal Aneuploidy (Q-Z) File of Apr 1, 2026 · source file | $1,528.10 | $2,183.00 | $421.32–$2,183.00 | 30% |
| The Methodist Hospitals Gary, IN · (219) 886-4000 Fetal Chrmoml Aneuploidy File of Aug 18, 2026 · source file | $1,659.00 | $2,370.00 | $759.05–$2,142.26 | 30% |
| Methodist Hospital-Southlake Merrillville, IN · (219) 886-4000 Fetal Chrmoml Aneuploidy File of Aug 18, 2026 · source file | $1,659.00 | $2,370.00 | $759.05–$2,142.26 | 30% |
| Palos Community Hospital Palos Heights, IL · (708) 923-4000 HB Ref Panorama Extended, Fetal Chromosomal Aneuploidy (Nat) File of Apr 1, 2026 · source file | $1,968.40 | $2,812.00 | $449.92–$2,812.00 | 30% |
| Northwestern Memorial Hospital Chicago, IL · (312) 926-2000 HB Ref Panorama Extended, Fetal Chromosomal Aneuploidy (Nat) File of Apr 1, 2026 · source file | $1,968.40 | $2,812.00 | $545.53–$2,812.00 | 30% |
| Northwestern Lake Forest Hospital Lake Forest, IL · (847) 234-5600 HB Ref Panorama Extended, Fetal Chromosomal Aneuploidy (Nat) File of Apr 1, 2026 · source file | $1,968.40 | $2,812.00 | $466.79–$2,812.00 | 30% |
| Northwestern Medicine Valley West Hospital Sandwich, IL · (815) 786-8484 HB Ref Panorama Extended, Fetal Chromosomal Aneuploidy (Nat) File of Apr 1, 2026 · source file | $1,968.40 | $2,812.00 | $534.28–$2,812.00 | 30% |
| Northwestern Medicine McHenry Hospital McHenry, IL · (815) 344-5000 HB Ref Panorama Extended, Fetal Chromosomal Aneuploidy (Nat) File of Apr 1, 2026 · source file | $1,968.40 | $2,812.00 | $542.72–$2,812.00 | 30% |
| Northwestern Medicine Central DuPage Hospital Winfield, IL · (630) 682-1600 HB Ref Panorama Extended, Fetal Chromosomal Aneuploidy (Nat) File of Apr 1, 2026 · source file | $1,968.40 | $2,812.00 | $194.03–$2,812.00 | 30% |
| Northwestern Medicine Delnor Hospital Geneva, IL · (630) 208-3000 HB Ref Panorama Extended, Fetal Chromosomal Aneuploidy (Nat) File of Apr 1, 2026 · source file | $1,968.40 | $2,812.00 | $418.99–$2,812.00 | 30% |
| Northwestern Medicine Kishwaukee Hospital DeKalb, IL · (815) 756-1521 HB Ref Panorama Extended, Fetal Chromosomal Aneuploidy (Nat) File of Apr 1, 2026 · source file | $1,968.40 | $2,812.00 | $514.60–$2,812.00 | 30% |
| Northwestern Medicine Central DuPage Hospital Winfield, IL · (630) 682-1600 HB Ref Informaseq Prenatal Test (Lc)+1 more line at this price File of Apr 1, 2026 · source file | $2,207.80 | $3,154.00 | $217.63–$3,154.00 | 30% |
| Northwestern Medicine Valley West Hospital Sandwich, IL · (815) 786-8484 HB Ref Fetal Chromosomal Aneuploidy File of Apr 1, 2026 · source file | $2,207.80 | $3,154.00 | $599.26–$3,154.00 | 30% |
| Northwestern Lake Forest Hospital Lake Forest, IL · (847) 234-5600 HB Ref Fetal Chromosomal Aneuploidy File of Apr 1, 2026 · source file | $2,207.80 | $3,154.00 | $523.56–$3,154.00 | 30% |
| Northwestern Medicine Kishwaukee Hospital DeKalb, IL · (815) 756-1521 HB Ref Fetal Chromosomal Aneuploidy File of Apr 1, 2026 · source file | $2,207.80 | $3,154.00 | $577.18–$3,154.00 | 30% |
| Northwestern Memorial Hospital Chicago, IL · (312) 926-2000 HB Ref Informaseq Prenatal Test (Lc)+1 more line at this price File of Apr 1, 2026 · source file | $2,207.80 | $3,154.00 | $611.88–$3,611.00 | 30% |
| Palos Community Hospital Palos Heights, IL · (708) 923-4000 HB Ref Fetal Chromosomal Aneuploidy File of Apr 1, 2026 · source file | $2,207.80 | $3,154.00 | $504.64–$3,154.00 | 30% |
| Northwestern Medicine Delnor Hospital Geneva, IL · (630) 208-3000 HB Ref Fetal Chromosomal Aneuploidy+1 more line at this price File of Apr 1, 2026 · source file | $2,207.80 | $3,154.00 | $469.95–$3,154.00 | 30% |
| Northwestern Medicine McHenry Hospital McHenry, IL · (815) 344-5000 HB Ref Fetal Chromosomal Aneuploidy File of Apr 1, 2026 · source file | $2,207.80 | $3,154.00 | $608.72–$3,154.00 | 30% |
| Mercyhealth Crystal Lake Hospital & Medical Center Crystal Lake, IL · (792) 220-5500 CHG FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ ANALYS File of Mar 1, 2026 · source file | $2,507.08 | $3,342.78 | — | 25% |
| Northwestern Lake Forest Hospital Lake Forest, IL · (847) 234-5600 HB Ref Informaseq Prenatal Test (Lc) File of Apr 1, 2026 · source file | $2,527.70 | $3,611.00 | $599.43–$3,611.00 | 30% |
Hospital The hospital that published the price, its city and the line exactly as written in its price file.
Cash price The hospital's own price for a patient paying without insurance (“discounted cash” in its price file). Hospitals must publish it under federal law, 45 CFR 180.50. Call to confirm it before booking. More
List price The hospital's full chargemaster price (“gross charge”) before any discount. Almost nobody pays it; the gap to the cash price shows what the self-pay discount is worth. More
Insurers pay The lowest and highest rates this hospital has agreed with insurance plans for the same item, from its price file. If the cash price is below what your plan pays and you have not met your deductible, paying cash can cost you less. More
Off list How much lower the cash price is than the list price.
No cash discount This line's cash price equals the hospital's full list price. Many hospitals still reduce bills for uninsured patients: ask the billing office for its self-pay discount in writing. More
Outpatient: lowest $400.00, median $714.71, highest $2,507.08 — a 6.3× difference within the same market.
As an inpatient, the same code is billed by 26 facilities here, median $477.50. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 33 of 33 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at 2 it is below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What NIPT prenatal DNA test is, what the price covers and why prices differ: NIPT prenatal DNA test explained.