Mpox vaccine (Jynneos) cost without insurance
The median hospital cash price for mpox and smallpox vaccine (Jynneos), 2-dose schedule is $452.53 across 164 US hospitals; most list between $183.04 and $1,061.38. The lowest outpatient cash price in any of 77 markets is $50.54. Prices come from each hospital's own price file; pick your area below to compare hospitals side by side.
Collected Sep 29, 2026 Each price links to its source file All Vaccine costs
Compared with Medicare
$0.01 is Medicare's 2026 national base rate for this service in a hospital outpatient department, including the patient's share and before the local wage adjustment. The median hospital cash price, $452.53 across 164 hospitals, is 45253.0× that.
Researchers often measure hospital prices as a multiple of Medicare's rate, and it is a concrete number to mention when you ask a hospital for a cash discount. Source: CMS.
Compared with the vaccine's list price
$260.13 (Jynneos) per dose is the manufacturer's private-sector price in the CDC vaccine price list: what a clinic or pharmacy pays for the vaccine itself. The median hospital cash price, $452.53 across 164 hospitals, is 1.7× that.
Giving the shot is billed separately (CPT 90471), and anyone who gives it adds a markup, so treat this as a floor: a concrete number to mention when you ask for a cash discount. Source: CDC.
What is CPT 90611?
Jynneos protects against mpox (monkeypox) and smallpox. It is two doses four weeks apart, recommended for people at higher risk of mpox exposure.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).
Why prices differ
Pharmacies, health departments and pediatric offices also give this vaccine, and hospital prices for the same dose vary widely.
What to ask
Ask whether the self-pay price for CPT 90611 includes giving the shot (90471) and how many doses the full series needs.
Prices by state
Median outpatient cash price, one line per hospital. Pick a state to see every hospital, cheapest first.
- California$189.28
- Connecticut$555.72
- District of Columbia$558.51
- Florida$510.71
- Hawaii$635.55
- Idaho$405.00
- Illinois$388.80
- Indiana$375.05
- Louisiana$1,636.25
- Maine$303.00
- Maryland$677.61
- Massachusetts$1,360.80
- Michigan$106.38
- Nebraska$448.99
- New Jersey$550.64
- New York$732.25
- North Carolina$654.75
- North Dakota$102.00
- Ohio$510.71
- Oregon$63.58
- Pennsylvania$614.40
- Rhode Island$385.00
- South Dakota$472.00
- Washington$86.94
- Wisconsin$492.63
Prices by market
Outpatient cash prices. “×” is how many times the highest price in that market exceeds the lowest.
| Market | Hospitals | Lowest | Median | Highest | × |
|---|---|---|---|---|---|
| Akron, OH | 1 | $510.71 | $510.71 | $510.71 | 1.0× |
| Albemarle, NC | 1 | $680.95 | $680.95 | $680.95 | 1.0× |
| Ann Arbor, MI | 1 | $106.38 | $106.38 | $106.38 | 1.0× |
| Atlantic City-Hammonton, NJ | 1 | $550.64 | $550.64 | $550.64 | 1.0× |
| Bryan, OH single city | 1 | $236.25 | $236.25 | $236.25 | 1.0× |
| Baltimore-Columbia-Towson, MD | 4 | $361.48 | $849.87 | $1,043.14 | 2.9× |
| Beaver Dam, WI | 1 | $492.63 | $492.63 | $492.63 | 1.0× |
| Bismarck, ND | 1 | $102.00 | $102.00 | $102.00 | 1.0× |
| Bloomington, IL | 1 | $388.80 | $388.80 | $388.80 | 1.0× |
| Boise City, ID | 2 | $405.00 | $405.00 | $405.00 | 1.0× |
| Boston-Cambridge-Newton, MA-NH | 3 | $310.50 | $1,360.80 | $1,360.80 | 4.4× |
| Bremerton-Silverdale-Port Orchard, WA | 1 | $118.97 | $118.97 | $118.97 | 1.0× |
| Buffalo-Cheektowaga, NY | 1 | $817.00 | $817.00 | $817.00 | 1.0× |
| Concord, NC single city | 1 | $654.75 | $654.75 | $654.75 | 1.0× |
| Canton-Massillon, OH | 1 | $510.71 | $510.71 | $510.71 | 1.0× |
| Champaign-Urbana, IL | 1 | $388.80 | $388.80 | $388.80 | 1.0× |
| Charlotte-Concord-Gastonia, NC-SC | 11 | $654.75 | $654.75 | $654.75 | 1.0× |
| Chicago-Naperville-Elgin, IL-IN | 5 | $157.51 | $190.67 | $1,085.40 | 6.9× |
| Cincinnati, OH-KY-IN | 3 | $380.34 | $540.62 | $540.62 | 1.4× |
| Cleveland, OH | 10 | $463.45 | $510.71 | $510.71 | 1.1× |
| Durham, NC single city | 1 | $456.07 | $456.07 | $456.07 | 1.0× |
| Danville, IL | 1 | $388.80 | $388.80 | $388.80 | 1.0× |
| Eau Claire, WI | 1 | $492.63 | $492.63 | $492.63 | 1.0× |
| Evansville, IN | 1 | $274.89 | $274.89 | $274.89 | 1.0× |
| Fresno, CA | 1 | $189.28 | $189.28 | $189.28 | 1.0× |
| Green Bay, WI | 1 | $333.82 | $333.82 | $333.82 | 1.0× |
| Hailey, ID | 1 | $405.00 | $405.00 | $405.00 | 1.0× |
| Kiryas Joel-Poughkeepsie-Newburgh, NY | 1 | $1,251.00 | $1,251.00 | $1,251.00 | 1.0× |
| Ladysmith, WI single city | 1 | $492.63 | $492.63 | $492.63 | 1.0× |
| Lexington Park, MD | 1 | $380.84 | $380.84 | $380.84 | 1.0× |
| Los Angeles-Long Beach-Anaheim, CA | 9 | $183.04 | $183.04 | $183.04 | 1.0× |
| McCall, ID single city | 1 | $405.00 | $405.00 | $405.00 | 1.0× |
| Minocqua, WI single city | 1 | $492.63 | $492.63 | $492.63 | 1.0× |
| Montpelier, OH single city | 1 | $236.25 | $236.25 | $236.25 | 1.0× |
| Miami-Fort Lauderdale-West Palm Beach, FL | 1 | $510.71 | $510.71 | $510.71 | 1.0× |
| Modesto, CA | 1 | $189.28 | $189.28 | $189.28 | 1.0× |
| Neillsville, WI single city | 1 | $492.63 | $492.63 | $492.63 | 1.0× |
| New Britain, CT single city | 1 | $555.72 | $555.72 | $555.72 | 1.0× |
| New Orleans-Metairie, LA | 7 | $1,632.00 | $1,636.25 | $2,462.50 | 1.5× |
| New Philadelphia-Dover, OH | 1 | $510.71 | $510.71 | $510.71 | 1.0× |
| New York-Newark-Jersey City, NY-NJ | 3 | $607.50 | $647.50 | $1,251.00 | 2.1× |
| Olney, IL single city | 1 | $388.80 | $388.80 | $388.80 | 1.0× |
| Ontario, CA single city | 1 | $183.04 | $183.04 | $183.04 | 1.0× |
| Omaha, NE-IA | 2 | $448.99 | $448.99 | $448.99 | 1.0× |
| Park Falls, WI single city | 1 | $492.63 | $492.63 | $492.63 | 1.0× |
| Peoria, IL | 4 | $388.80 | $388.80 | $388.80 | 1.0× |
| Pittsburgh, PA | 1 | $614.40 | $614.40 | $614.40 | 1.0× |
| Portland-South Portland, ME | 1 | $303.00 | $303.00 | $303.00 | 1.0× |
| Portland-Vancouver-Hillsboro, OR-WA | 2 | $63.58 | $63.58 | $63.58 | 1.0× |
| Providence-Warwick, RI-MA | 2 | $385.00 | $385.00 | $385.00 | 1.0× |
| Pullman, WA | 1 | $218.11 | $218.11 | $218.11 | 1.0× |
| Richmond, CA single city | 1 | $189.28 | $189.28 | $189.28 | 1.0× |
| Raleigh-Cary, NC | 1 | $456.07 | $456.07 | $456.07 | 1.0× |
| Rapid City, SD | 3 | $472.00 | $472.00 | $472.00 | 1.0× |
| Rice Lake, WI | 1 | $492.63 | $492.63 | $492.63 | 1.0× |
| Riverside-San Bernardino-Ontario, CA | 3 | $183.04 | $183.04 | $183.04 | 1.0× |
| Rochester, NY | 1 | $607.75 | $607.75 | $607.75 | 1.0× |
| Sparta, NC single city | 1 | $1,722.00 | $1,722.00 | $1,722.00 | 1.0× |
| Sacramento-Roseville-Folsom, CA | 3 | $189.28 | $189.28 | $189.28 | 1.0× |
| San Diego-Chula Vista-Carlsbad, CA | 4 | $183.04 | $183.04 | $769.82 | 4.2× |
| San Francisco-Oakland-Fremont, CA | 11 | $189.28 | $189.28 | $1,620.00 | 8.6× |
| San Jose-Sunnyvale-Santa Clara, CA | 3 | $189.28 | $189.28 | $1,069.20 | 5.6× |
| Santa Rosa-Petaluma, CA | 1 | $189.28 | $189.28 | $189.28 | 1.0× |
| Seattle-Tacoma-Bellevue, WA | 7 | $77.70 | $84.60 | $130.82 | 1.7× |
| Shelby-Kings Mountain, NC | 1 | $654.75 | $654.75 | $654.75 | 1.0× |
| Slidell-Mandeville-Covington, LA | 1 | $1,636.25 | $1,636.25 | $1,636.25 | 1.0× |
| Spearfish, SD | 2 | $472.00 | $472.00 | $472.00 | 1.0× |
| Stevens Point-Plover, WI | 1 | $492.63 | $492.63 | $492.63 | 1.0× |
| Stockton-Lodi, CA | 1 | $189.28 | $189.28 | $189.28 | 1.0× |
| Twin Falls, ID | 1 | $405.00 | $405.00 | $405.00 | 1.0× |
| Urban Honolulu, HI | 1 | $635.55 | $635.55 | $635.55 | 1.0× |
| Vallejo, CA | 2 | $189.28 | $189.28 | $189.28 | 1.0× |
| Vincennes, IN | 1 | $475.20 | $475.20 | $475.20 | 1.0× |
| Washington-Arlington-Alexandria, DC-VA-MD-WV | 5 | $473.15 | $558.51 | $677.61 | 1.4× |
| Wausau, WI | 1 | $492.63 | $492.63 | $492.63 | 1.0× |
| Wenatchee-East Wenatchee, WA | 1 | $50.54 | $50.54 | $50.54 | 1.0× |
| Wisconsin Rapids-Marshfield, WI | 1 | $492.63 | $492.63 | $492.63 | 1.0× |
Common questions
What is CPT code 90611?
CPT 90611 is the billing code for mpox and smallpox vaccine (Jynneos), 2-dose schedule. Jynneos protects against mpox (monkeypox) and smallpox. It is two doses four weeks apart, recommended for people at higher risk of mpox exposure.
Is the mpox vaccine free?
It was free while the government supplied it; since 2024 it is sold commercially, and insurance usually covers it for people the CDC recommends it for. Health departments may still offer free doses.
Does insurance cover it?
Most health plans must cover vaccines the CDC recommends for your age with nothing to pay when you use an in-network provider.
How much does Medicare pay for CPT 90611 (Mpox vaccine (Jynneos))?
$0.01 is Medicare's 2026 national base rate for this service in a hospital outpatient department, including the patient's share and before the local wage adjustment. The median hospital cash price, $452.53 across 164 hospitals, is 45253.0× that.
What does a dose of the mpox vaccine (Jynneos) cost a clinic or pharmacy?
$260.13 (Jynneos) per dose is the manufacturer's private-sector price in the CDC vaccine price list: what a clinic or pharmacy pays for the vaccine itself. The median hospital cash price, $452.53 across 164 hospitals, is 1.7× that. Giving the shot is billed separately (CPT 90471).
Other vaccine prices
Median hospital cash price, one per hospital.