Mpox vaccine (Jynneos) cost in South Dakota
In South Dakota, 5 hospitals publish a cash price for mpox and smallpox vaccine (Jynneos), 2-dose schedule: from $472.00 to $472.00, with a median of $472.00. The lowest price is at Monument Health Custer Hospital (Custer) and 4 other hospitals.
Outpatient cash prices, one line per hospital — its lowest listed price for code 90611. Prices for both sides of the body and inpatient prices are not mixed in. Collected Oct 2, 2026. See them on a map
Hospitals in South Dakota, cheapest first
| Hospital | Cash price | List price | File date |
|---|---|---|---|
| Monument Health Custer Hospital lowest Custer · Rapid City, SD Smallpox and monkeypox vaccine, attenuated vaccinia virus, live, non-replicating, preservative free, 0.5 mL dosage, suspension, for subcutaneous use | $472.00 | $590.00 | Sep 1, 2026 source file |
| Monument Health Lead-Deadwood Hospital lowest Deadwood · Spearfish, SD Smallpox and monkeypox vaccine, attenuated vaccinia virus, live, non-replicating, preservative free, 0.5 mL dosage, suspension, for subcutaneous use | $472.00 | $590.00 | Sep 1, 2026 source file |
| Monument Health Rapid City Hospital lowest Rapid City · Rapid City, SD Smallpox and monkeypox vaccine, attenuated vaccinia virus, live, non-replicating, preservative free, 0.5 mL dosage, suspension, for subcutaneous use | $472.00 | $590.00 | Sep 1, 2026 source file |
| Monument Health Spearfish Hospital lowest Spearfish · Spearfish, SD Smallpox and monkeypox vaccine, attenuated vaccinia virus, live, non-replicating, preservative free, 0.5 mL dosage, suspension, for subcutaneous use | $472.00 | $590.00 | Sep 1, 2026 source file |
| Monument Health Sturgis Hospital lowest Sturgis · Rapid City, SD Smallpox and monkeypox vaccine, attenuated vaccinia virus, live, non-replicating, preservative free, 0.5 mL dosage, suspension, for subcutaneous use | $472.00 | $590.00 | Sep 1, 2026 source file |
By metro area
Each metro page compares every listing, including prices for both sides of the body.
| Metro area | Hospitals | Lowest | Median |
|---|---|---|---|
| Rapid City, SD | 3 | $472.00 | $472.00 |
| Spearfish, SD | 2 | $472.00 | $472.00 |
What it is
Jynneos protects against mpox (monkeypox) and smallpox. It is two doses four weeks apart, recommended for people at higher risk of mpox exposure.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).
Mpox and smallpox vaccine (Jynneos), 2-dose schedule in other states
- California$189.28
- Connecticut$555.72
- District of Columbia$552.83
- Florida$510.71
- Hawaii$635.55
- Idaho$405.00
- Illinois$388.80
- Indiana$375.05
- Louisiana$1,636.25
- Maine$303.00
- Maryland$677.61
- Massachusetts$1,360.80
- Michigan$106.38
- Nebraska$448.99
- New Jersey$550.64
- New York$607.75
- North Carolina$654.75
- North Dakota$102.00
- Ohio$510.71
- Oregon$63.58
- Pennsylvania$614.40
- Rhode Island$385.00
- Washington$86.94
- Wisconsin$492.63
Median cash price across the state's hospitals.