Hepatitis B vaccine (Heplisav-B) cost in Chicago, IL — inpatient
In Chicago-Naperville-Elgin, IL-IN, 15 hospitals list a cash price for hepatitis B vaccine, adult, 2-dose schedule (Heplisav-B) as an inpatient: from $68.21 to $1,831.62, with a median of $185.29. The lowest listed price is at Gottlieb Memorial Hospital and 1 other hospital — $117.08 less than the median here. Across Illinois, the median is $224.28 at 39 hospitals.
Cash prices at 15 facilities across 12 cities for code 90739, as an inpatient (admitted to hospital) . Collected Sep 27, 2026; the hospital files themselves were last updated between Mar 31, 2026 and Apr 1, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Chicago-Naperville-Elgin, IL-IN.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list |
|---|---|---|---|---|
| Gottlieb Memorial Hospital lowest Melrose Park, IL · (708) 681-3200 Hepatitis B Adult Heplisav-B 2-Dose Sch Im Inj (Fc)+1 more line at this price File of Mar 31, 2026 · source file | $68.21 | $359.00 | $108.06–$300.84 | 81% |
| MacNeal Hospital lowest Berwyn, IL · (708) 783-9100 Hepatitis B Adult Heplisav-B 2-Dose Sch Im Inj (Fc) File of Mar 31, 2026 · source file | $68.21 | $359.00 | $68.21–$497.22 | 81% |
| Loyola University Medical Center Maywood, IL · (708) 216-9000 Hepatitis B Adult Heplisav-B 2-Dose Sch Im Inj (Fc) File of Mar 31, 2026 · source file | $82.57 | $359.00 | $124.57–$378.39 | 77% |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Hc Hepb Vacc 2 Dose Adult Im Employee Health File of Apr 1, 2026 · source file | $145.00 | $145.00 | — | — |
| Uchicago Medicine AdventHealth La Grange La Grange, IL · (708) 352-1200 HEPATITIS B VAC RECOMB ADJ 20 MCG/0.5ML IM SOSY File of Apr 1, 2026 · source file | $185.29 | $741.14 | — | 75% |
| Uchicago Medicine AdventHealth Glenoaks Glendale Heights, IL · (630) 545-8000 HEPATITIS B VAC RECOMB ADJ 20 MCG/0.5ML IM SOSY File of Apr 1, 2026 · source file | $185.29 | $741.14 | — | 75% |
| Uchicago Medicine AdventHealth Bolingbrook Bolingbrook, IL · (630) 312-5000 HEPATITIS B VAC RECOMB ADJ 20 MCG/0.5ML IM SOSY File of Apr 1, 2026 · source file | $185.29 | $741.14 | — | 75% |
| Uchicago Medicine AdventHealth Hinsdale Hinsdale, IL · (630) 856-9000 HEPATITIS B VAC RECOMB ADJ 20 MCG/0.5ML IM SOSY File of Apr 1, 2026 · source file | $185.29 | $741.14 | — | 75% |
| NorthShore University HealthSystems Glenbrook Hospital Glenview, IL Hepatitis B Vacc Adult 2 Dose Im source file | $212.55 | $327.00 | $53.30–$174.95 | 35% |
| NorthShore University HealthSystems Skokie Hospital Skokie, IL Hepatitis B Vacc Adult 2 Dose Im source file | $212.55 | $327.00 | $53.30–$174.95 | 35% |
| Presence Saint Joseph Hospital - Chicago Chicago, IL · (773) 665-3000 HEPATITIS B VAC RECOMB ADJ 20 MCG/0.5ML IM SOSY source file | $302.43 | $916.46 | $195.54–$458.23 | 67% |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Pr Hepb Vaccine Adult 2/4 Dose Schedule For Im Use+1 more line at this price File of Apr 1, 2026 · source file | $306.00 | $306.00 | — | — |
| Northshore University Healthsystem - Evanston Hospital Evanston, IL · (847) 570-2000 HEPATITIS B VACC ADULT 2 DOSE IM File of Apr 1, 2026 · source file | $362.00 | $362.00 | — | — |
| Swedish Covenant Health Chicago, IL · (773) 878-8200 HEPATITIS B VACC ADULT 2 DOSE IM File of Apr 1, 2026 · source file | $362.00 | $362.00 | — | — |
| Endeavor Health Highland Park Hospital Highland Park, IL HEPATITIS B VACC ADULT 2 DOSE IM File of Apr 1, 2026 · source file | $362.00 | $362.00 | — | — |
| Uchicago Medicine AdventHealth Hinsdale Hinsdale, IL · (630) 856-9000 HEPATITIS B VACCINE 20 MCG/0.5 ML-ADJUVANT CPG 1018 (PF) IM SYRINGE File of Apr 1, 2026 · source file | $626.12 | $1,043.53 | — | 40% |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 NDC Description Not Available File of Apr 1, 2026 · source file | $1,001.62 | $1,001.62 | — | — |
| John H. Stroger, Jr. Hospital Chicago, IL · (312) 864-6000 HEPATITIS B ADULT VACCINE (HEPLISAV-B) 20 MCG/0.5 ML source file | $1,831.62 | $2,616.60 | $183.79–$2,093.28 | 30% |
Inpatient: lowest $68.21, median $185.29, highest $1,831.62 — a 26.9× difference within the same market.
As an outpatient, the same code is billed by 27 facilities here, median $320.30 — that is the price to compare if you are not being admitted.
Cash or insurance?
At 4 of 6 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at 1 it is below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
Heplisav-B is a hepatitis B vaccine for adults that needs only two doses, one month apart, instead of three over six months.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).