AFP test cost in Naples, FL
In Naples-Marco Island, FL, 4 hospitals list a cash price for alpha-fetoprotein (AFP) blood test: from $8.61 to $38.40, with a median of $10.04. The lowest listed price is at Physicians Regional - Collier Boulevard — $1.43 less than the median here. Across Florida, the median is $34.03 at 166 hospitals.
Cash prices at 4 facilities for code 82105, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 27, 2026; the hospital files themselves were last updated between Apr 1, 2026 and Jul 1, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Naples-Marco Island, FL.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list |
|---|---|---|---|---|
| Physicians Regional - Collier Boulevard lowest Naples, FL Q16133 AFP SERUM File of Apr 1, 2026 · source file | $8.61 | $47.82 | $8.61–$86.37 | 82% |
| Physicians Regional Medical Center - Pine Ridge Naples, FL · (239) 304-5145 Q16133 AFP SERUM File of Apr 1, 2026 · source file | $10.04 | $47.82 | $8.61–$86.37 | 79% |
| Physicians Regional Medical Center - Pine Ridge Naples, FL · (239) 304-5145 Q16133 AFP SERUM File of Apr 1, 2026 · source file | $10.04 | $47.82 | $8.61–$86.37 | 79% |
| Physicians Regional - Collier Boulevard Naples, FL Q237 AFP TUMR MRK IA File of Apr 1, 2026 · source file | $11.34 | $62.99 | $11.34–$86.37 | 82% |
| Physicians Regional Medical Center - Pine Ridge Naples, FL · (239) 304-5145 Q237 AFP TUMR MRK IA File of Apr 1, 2026 · source file | $13.23 | $62.99 | $11.34–$86.37 | 79% |
| Physicians Regional Medical Center - Pine Ridge Naples, FL · (239) 304-5145 Q237 AFP TUMR MRK IA File of Apr 1, 2026 · source file | $13.23 | $62.99 | $11.34–$86.37 | 79% |
| Physicians Regional - Collier Boulevard Naples, FL Q5059 MAT SER AFP IA File of Apr 1, 2026 · source file | $14.09 | $78.25 | $14.08–$86.37 | 82% |
| Physicians Regional Medical Center - Pine Ridge Naples, FL · (239) 304-5145 Q5059 MAT SER AFP IA File of Apr 1, 2026 · source file | $16.43 | $78.25 | $14.08–$86.37 | 79% |
| Physicians Regional Medical Center - Pine Ridge Naples, FL · (239) 304-5145 Q5059 MAT SER AFP IA File of Apr 1, 2026 · source file | $16.43 | $78.25 | $14.08–$86.37 | 79% |
| Naples Community Hospital Naples, FL · (239) 624-5000 HC ALPHA-FETOPROTEIN SERUM File of Jul 1, 2026 · source file | $38.40 | $96.00 | — | 60% |
Outpatient: lowest $8.61, median $10.04, highest $38.40 — a 4.5× difference within the same market.
As an inpatient, the same code is billed by 4 facilities here, median $11.48. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 3 of 3 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
An AFP test measures a protein made by the liver and by a developing baby. In adults it is used to watch for liver cancer in people with cirrhosis and to follow some testicular cancers.
What the price covers
The price usually covers running the test. The blood draw (36415) is often billed as a separate line.