AFP test cost in Orlando, FL
In Orlando-Kissimmee-Sanford, FL, 15 hospitals list a cash price for alpha-fetoprotein (AFP) blood test: from $10.00 to $181.10, with a median of $36.25. The lowest listed price is at Orlando Health Central and 3 other hospitals — $26.25 less than the median here. Across Florida, the median is $34.30 at 165 hospitals.
Cash prices at 15 facilities across 10 cities for code 82105, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 29, 2026; the hospital files themselves were last updated between Mar 31, 2026 and Sep 1, 2026.
Lowest$10.00Orlando Health Central + 3 more
Median$36.25half pay less
Highest$181.10in this market
Difference18.1×highest vs lowest
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Orlando-Kissimmee-Sanford, FL.
median
Lowest $10.00Highest $683.15
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list | File date |
|---|---|---|---|---|---|
| Orlando Health Central lowest Ocoee, FL · (407) 296-1000 Hb Afp Maternal Screen-Ref | $10.00 | $25.00 | — | 60% | Apr 1, 2026 source file |
| South Lake Hospital lowest Clermont, FL · (352) 394-4071 Hb Afp Maternal Screen-Ref | $10.00 | $25.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health lowest Orlando, FL · (321) 841-5111 Hb Afp Maternal Screen-Ref | $10.00 | $25.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health St Cloud Hospital lowest Saint Cloud, FL · (407) 892-2135 Hb Afp Maternal Screen-Ref | $10.00 | $25.00 | — | 60% | Apr 1, 2026 source file |
| HCA Florida Lake Monroe Hospital Casselberry, FL · (407) 321-4500 ALPHA FETOPROT SERUM MAT | $11.00 | $11.00 | $0.79–$9.90 | — | Sep 1, 2026 source file |
| Orlando Health Central Ocoee, FL · (407) 296-1000 Hb Alpha-Fetoprotein Serum (8004) Genzyme-Exc | $13.20 | $33.00 | — | 60% | Apr 1, 2026 source file |
| South Lake Hospital Clermont, FL · (352) 394-4071 Hb Alpha-Fetoprotein Serum (8004) Genzyme-Exc | $13.20 | $33.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health St Cloud Hospital Saint Cloud, FL · (407) 892-2135 Hb Alpha-Fetoprotein Serum (8004) Genzyme-Exc | $13.20 | $33.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health Orlando, FL · (321) 841-5111 Hb Alpha-Fetoprotein Serum (8004) Genzyme-Exc | $13.20 | $33.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health St Cloud Hospital Saint Cloud, FL · (407) 892-2135 Hb Alpha-Fetoprotein Serum | $13.60 | $34.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health Orlando, FL · (321) 841-5111 Hb Alpha-Fetoprotein Serum | $13.60 | $34.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health Central Ocoee, FL · (407) 296-1000 Hb Afp Tumor | $13.60 | $34.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health Central Ocoee, FL · (407) 296-1000 Hb Alpha-Fetoprotein Serum | $13.60 | $34.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health Orlando, FL · (321) 841-5111 Hb Afp Tumor | $13.60 | $34.00 | — | 60% | Apr 1, 2026 source file |
| South Lake Hospital Clermont, FL · (352) 394-4071 Hb Afp Tumor | $13.60 | $34.00 | — | 60% | Apr 1, 2026 source file |
| South Lake Hospital Clermont, FL · (352) 394-4071 Hb Alpha-Fetoprotein Serum | $13.60 | $34.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health St Cloud Hospital Saint Cloud, FL · (407) 892-2135 Hb Afp Tumor | $13.60 | $34.00 | — | 60% | Apr 1, 2026 source file |
| HCA Florida Poinciana Hospital Davenport, FL · (407) 530-2000 ALPHA FETOPROT SERUM MAT | $17.25 | $17.25 | $1.24–$14.66 | — | Sep 1, 2026 source file |
| Orlando Health St Cloud Hospital Saint Cloud, FL · (407) 892-2135 Hb Msafp-Ref | $25.60 | $64.00 | — | 60% | Apr 1, 2026 source file |
| South Lake Hospital Clermont, FL · (352) 394-4071 Hb Msafp-Ref | $25.60 | $64.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health Central Ocoee, FL · (407) 296-1000 Hb Msafp-Ref | $25.60 | $64.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health Orlando, FL · (321) 841-5111 Hb Msafp-Ref | $25.60 | $64.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health Central Ocoee, FL · (407) 296-1000 Hb Afp (Afp Quad Screen)-Ref | $26.40 | $66.00 | — | 60% | Apr 1, 2026 source file |
| South Lake Hospital Clermont, FL · (352) 394-4071 Hb Afp (Afp Quad Screen)-Ref | $26.40 | $66.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health Orlando, FL · (321) 841-5111 Hb Afp (Afp Quad Screen)-Ref | $26.40 | $66.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health St Cloud Hospital Saint Cloud, FL · (407) 892-2135 Hb Afp (Afp Quad Screen)-Ref | $26.40 | $66.00 | — | 60% | Apr 1, 2026 source file |
| Ucf Lake Nona Hospital Orlando, FL · (850) 523-2115 ALPHA FETOPROT SERUM MAT | $36.14 | $36.14 | $2.60–$32.53 | — | Sep 1, 2026 source file |
| HCA Florida Osceola Hospital St. Cloud, FL · (407) 846-2266 ALPHA FETOPROT SERUM MAT | $36.25 | $36.25 | $2.61–$36.25 | — | Sep 1, 2026 source file |
| Nemours Childrens Hospital, Florida Orlando, FL · (407) 567-4000 Alpha Fetoprotein | $37.00 | $37.00 | — | — | — source file |
| Nemours Childrens Hospital, Florida Orlando, FL · (407) 567-4000 Alpha Fetoprotein | $37.00 | $37.00 | — | — | — source file |
| Orlando Health Central Ocoee, FL · (407) 296-1000 Hb Alpha-Fetoprotein Serum-(Inter Scrn)-(8026)-Exc | $47.20 | $118.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health Orlando, FL · (321) 841-5111 Hb Alpha-Fetoprotein Serum-(Inter Scrn)-(8026)-Exc | $47.20 | $118.00 | — | 60% | Apr 1, 2026 source file |
| Orlando Health St Cloud Hospital Saint Cloud, FL · (407) 892-2135 Hb Alpha-Fetoprotein Serum-(Inter Scrn)-(8026)-Exc | $47.20 | $118.00 | — | 60% | Apr 1, 2026 source file |
| South Lake Hospital Clermont, FL · (352) 394-4071 Hb Alpha-Fetoprotein Serum-(Inter Scrn)-(8026)-Exc | $47.20 | $118.00 | — | 60% | Apr 1, 2026 source file |
| Oviedo Medical Center Orlando, FL · (615) 850-6055 ALPHA FETOPROT SERUM | $63.00 | $63.00 | $4.54–$31.50 | — | Sep 1, 2026 source file |
| Oviedo Medical Center Orlando, FL · (615) 850-6055 ALPHA FETOPROT SERUM MAT | $63.00 | $63.00 | $4.54–$31.50 | — | Sep 1, 2026 source file |
| The Villages Regional Hospital The Villages, FL · (352) 751-8000 HB AFP MATERNAL SERUM | $67.10 | $122.00 | $6.09–$18.45 | 45% | Mar 31, 2026 source file |
| UF Health Leesburg Hospital Leesburg, FL · (352) 323-5762 HB AFP MATERNAL SERUM | $67.10 | $122.00 | $54.90–$84.55 | 45% | Mar 31, 2026 source file |
| UF Health Leesburg Hospital Leesburg, FL · (352) 323-5762 HB ALPHA-FETOPROTEIN SERUM TMR MRKR | $67.10 | $122.00 | $54.90–$84.55 | 45% | Mar 31, 2026 source file |
| The Villages Regional Hospital The Villages, FL · (352) 751-8000 HB ALPHA-FETOPROTEIN SERUM TMR MRKR | $67.10 | $122.00 | $54.90–$101.26 | 45% | Mar 31, 2026 source file |
| HCA Florida Lake Monroe Hospital Casselberry, FL · (407) 321-4500 ALPHA FETOPROT SERUM | $75.00 | $75.00 | $5.40–$67.50 | — | Sep 1, 2026 source file |
| AdventHealth Orlando Orlando, FL · (407) 303-1976 HC INTEGRATED SCREEN 2ND TRIMESTER - AFP | $110.00 | $110.00 | — | — | Apr 1, 2026 source file |
| AdventHealth Orlando Orlando, FL · (407) 303-1976 HC ALPHA FETOPROTEIN (AFP) TUMOR MARKER | $110.00 | $110.00 | — | — | Apr 1, 2026 source file |
| AdventHealth Orlando Orlando, FL · (407) 303-1976 HC ALPHA FETOPROTEIN, TUMOR MARKER - QWDL | $110.00 | $110.00 | — | — | Apr 1, 2026 source file |
| AdventHealth Orlando Orlando, FL · (407) 303-1976 HC ALPHA FETOPROTEIN (AFP) TUMOR MARKER SERUM - ARUP | $110.00 | $110.00 | — | — | Apr 1, 2026 source file |
| AdventHealth Orlando Orlando, FL · (407) 303-1976 HC MATERNAL QUAD SCREEN - AFP | $110.00 | $110.00 | — | — | Apr 1, 2026 source file |
| AdventHealth Orlando Orlando, FL · (407) 303-1976 HC ALPHA FETOPROTEIN MATERNAL SERUM - ARUP | $110.00 | $110.00 | — | — | Apr 1, 2026 source file |
| Nemours Childrens Hospital, Florida Orlando, FL · (407) 567-4000 Alpha Fetoprotein Referred | $116.00 | $116.00 | — | — | — source file |
| Nemours Childrens Hospital, Florida Orlando, FL · (407) 567-4000 Alpha Fetoprotein Referred | $116.00 | $116.00 | — | — | — source file |
| PAM Rehabilitation Hospital of Tavares Tavares, FL Alpha-Fetoprotein Serum | $167.70 | $167.70 | $12.58–$142.55 | — | Aug 6, 2026 source file |
| AdventHealth Waterman Tavares, FL · (352) 253-3368 HC ALPHA FETOPROTEIN MATERNAL SERUM - ARUP | $181.10 | $181.10 | — | — | Apr 1, 2026 source file |
| HCA Florida Poinciana Hospital Davenport, FL · (407) 530-2000 ALPHA FETOPROT SERUM | $295.25 | $295.25 | $21.26–$250.96 | — | Sep 1, 2026 source file |
| AdventHealth Waterman Tavares, FL · (352) 253-3368 HC ALPHA FETOPROTEIN (AFP) TUMOR MARKER | $299.83 | $299.83 | — | — | Apr 1, 2026 source file |
| Ucf Lake Nona Hospital Orlando, FL · (850) 523-2115 ALPHA FETOPROT SERUM | $667.41 | $667.41 | $48.05–$600.67 | — | Sep 1, 2026 source file |
| HCA Florida Osceola Hospital St. Cloud, FL · (407) 846-2266 ALPHA FETOPROT SERUM | $683.15 | $683.15 | $49.19–$683.15 | — | Sep 1, 2026 source file |
Outpatient: lowest $10.00, median $36.25, highest $181.10 — a 18.1× difference within the same market.
As an inpatient, the same code is billed by 8 facilities here, median $23.50. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 1 of 8 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
An AFP test measures a protein made by the liver and by a developing baby. In adults it is used to watch for liver cancer in people with cirrhosis and to follow some testicular cancers.
What the price covers
The price usually covers running the test. The blood draw (36415) is often billed as a separate line.