AFP test cost in Jacksonville, FL
In Jacksonville, FL, 8 hospitals list a cash price for alpha-fetoprotein (AFP) blood test: from $27.20 to $318.38, with a median of $37.10. The lowest listed price is at Ascension St Vincent's Southside and 3 other hospitals — $9.90 less than the median here. Across Florida, the median is $34.30 at 165 hospitals.
Cash prices at 8 facilities across 4 cities for code 82105, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 29, 2026; the hospital files themselves were last updated between Mar 31, 2026 and Sep 1, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Jacksonville, FL.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list | File date |
|---|---|---|---|---|---|
| Ascension St Vincent's Southside lowest Jacksonville, FL · (904) 296-3700 ALPHAFETOPROTEIN SERUM | $27.20 | $73.50 | $14.70–$73.50 | 63% | — source file |
| Ascension St Vincent's Southside lowest Jacksonville, FL · (904) 296-3700 ALPHAFETOPROTEIN SERUM | $27.20 | $73.50 | $14.70–$73.50 | 63% | — source file |
| Ascension St Vincent's St Johns County lowest Saint Johns, FL · (904) 450-6020 ALPHAFETOPROTEIN SERUM | $27.20 | $73.50 | $14.70–$73.50 | 63% | — source file |
| Ascension St Vincent's St Johns County lowest Saint Johns, FL · (904) 450-6020 ALPHAFETOPROTEIN SERUM | $27.20 | $73.50 | $14.70–$73.50 | 63% | — source file |
| St. Vincent's Medical Center-Clay County lowest Middleburg, FL · (904) 602-1000 ALPHAFETOPROTEIN SERUM | $27.20 | $73.50 | $14.70–$73.50 | 63% | — source file |
| Ascension St Vincent's Riverside lowest Jacksonville, FL · (904) 308-7300 ALPHAFETOPROTEIN SERUM | $27.20 | $73.50 | $14.70–$41.93 | 63% | — source file |
| Ascension St Vincent's Riverside lowest Jacksonville, FL · (904) 308-7300 ALPHAFETOPROTEIN SERUM | $27.20 | $73.50 | $14.70–$41.93 | 63% | — source file |
| St. Vincent's Medical Center-Clay County lowest Middleburg, FL · (904) 602-1000 ALPHAFETOPROTEIN SERUM | $27.20 | $73.50 | $14.70–$73.50 | 63% | — source file |
| HCA Florida Memorial Hospital Jacksonville, FL · (904) 702-6111 ALPHA FETOPROT SERUM MAT | $47.00 | $47.00 | $3.95–$42.30 | — | Sep 1, 2026 source file |
| University of Florida Health in Jacksonville Jacksonville, FL · (904) 244-4000 HB ALPHA-FETOPROTEIN SERUM TMR MRKR | $48.46 | $88.11 | $6.70–$19.62 | 45% | Mar 31, 2026 source file |
| University of Florida Health in Jacksonville Jacksonville, FL · (904) 244-4000 HB ALPHA-FETOPROTEIN | $52.80 | $96.00 | $6.70–$19.62 | 45% | Mar 31, 2026 source file |
| ED Fraser Memorial Hospital Macclenny, FL · (904) 259-3151 ALPHA FETOPROTEIN (AFP) | $166.00 | $166.00 | $16.43 | — | — source file |
| HCA Florida Orange Park Hospital Jacksonville, FL · (904) 276-8500 Alpha-fetoprotein (AFP); serum UNSCHEDULED | $318.38 | $318.38 | $95.06–$97.06 | — | Sep 1, 2026 source file |
| HCA Florida Orange Park Hospital Jacksonville, FL · (904) 276-8500 ALPHA FETOPROT SERUM | $318.38 | $318.38 | $26.74–$286.54 | — | Sep 1, 2026 source file |
| HCA Florida Orange Park Hospital Jacksonville, FL · (904) 276-8500 Alpha-fetoprotein (AFP); serum | $318.38 | $318.38 | $16.77 | — | Sep 1, 2026 source file |
| HCA Florida Memorial Hospital Jacksonville, FL · (904) 702-6111 ALPHA FETOPROT SERUM | $339.00 | $339.00 | $28.48–$305.10 | — | Sep 1, 2026 source file |
Outpatient: lowest $27.20, median $37.10, highest $318.38 — a 11.7× difference within the same market.
As an inpatient, the same code is billed by 7 facilities here, median $27.20. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 4 of 8 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
An AFP test measures a protein made by the liver and by a developing baby. In adults it is used to watch for liver cancer in people with cirrhosis and to follow some testicular cancers.
What the price covers
The price usually covers running the test. The blood draw (36415) is often billed as a separate line.
21 rows held back from this comparison
They are priced below $1 or below a tenth of the national median for code 82105 ($82.26). Such a line is almost always a physician's fee billed separately, an assistant's share or a placeholder — a real charge, but not the price of the procedure itself.
| Ascension St Vincent's Riverside Jacksonville, FLREF ALPHAFETOPROTEIN | $2.22 | file |
| Ascension St Vincent's Riverside Jacksonville, FLREF TRIPLE SCN ALPHA FETO PROTEIN | $2.22 | file |
| Ascension St Vincent's Southside Jacksonville, FLREF ALPHAFETOPROTEIN | $2.22 | file |
| St. Vincent's Medical Center-Clay County Middleburg, FLREF ALPHAFETOPROTEIN | $2.22 | file |
| St. Vincent's Medical Center-Clay County Middleburg, FLREF TRIPLE SCN ALPHA FETO PROTEIN | $2.22 | file |
| Ascension St Vincent's Southside Jacksonville, FLREF TRIPLE SCN ALPHA FETO PROTEIN | $2.22 | file |
| Ascension St Vincent's St Johns County Saint Johns, FLREF TRIPLE SCN ALPHA FETO PROTEIN | $2.22 | file |
| Ascension St Vincent's St Johns County Saint Johns, FLREF ALPHAFETOPROTEIN | $2.22 | file |
| Ascension St Vincent's Southside Jacksonville, FLREF ALPHA-FETOPROTN MATERNAL(MEM) | $3.33 | file |
| Ascension St Vincent's St Johns County Saint Johns, FLREF ALPHA-FETOPROTN MATERNAL(MEM) | $3.33 | file |
| Ascension St Vincent's Riverside Jacksonville, FLREF ALPHA-FETOPROTN MATERNAL(MEM) | $3.33 | file |
| St. Vincent's Medical Center-Clay County Middleburg, FLREF ALPHA-FETOPROTN MATERNAL(MEM) | $3.33 | file |
| University of Florida Health in Jacksonville Jacksonville, FLHB ALPHA FETOPROTEIN (AFP) | $4.40 | file |
| Ascension St Vincent's Southside Jacksonville, FLREF PENTA SCREEN AFP SERUM | $4.81 | file |
| St. Vincent's Medical Center-Clay County Middleburg, FLREF PENTA SCREEN AFP SERUM | $4.81 | file |
| Ascension St Vincent's St Johns County Saint Johns, FLREF PENTA SCREEN AFP SERUM | $4.81 | file |
| Ascension St Vincent's Riverside Jacksonville, FLREF PENTA SCREEN AFP SERUM | $4.81 | file |
| Ascension St Vincent's St Johns County Saint Johns, FLREF MATERNAL AFP-A | $5.18 | file |
| Ascension St Vincent's Riverside Jacksonville, FLREF MATERNAL AFP-A | $5.18 | file |
| Ascension St Vincent's Southside Jacksonville, FLREF MATERNAL AFP-A | $5.18 | file |
| St. Vincent's Medical Center-Clay County Middleburg, FLREF MATERNAL AFP-A | $5.18 | file |