Hepatitis B vaccine (Heplisav-B) cost in Houston, TX
In Houston-Pasadena-The Woodlands, TX, 9 hospitals list a cash price for hepatitis B vaccine, adult, 2-dose schedule (Heplisav-B): from $97.73 to $627.10, with a median of $195.39. The lowest listed price is at Harris Health and 1 other hospital — $97.66 less than the median here. Across Texas, the median is $402.20 at 61 hospitals.
Cash prices at 9 facilities across 6 cities for code 90739, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 28, 2026; the hospital files themselves were last updated between Feb 28, 2026 and Sep 1, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Houston-Pasadena-The Woodlands, TX.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list |
|---|---|---|---|---|
| Harris Health lowest Houston, TX · (713) 873-2000 HEPATITIS B VACCINE 20 MCG/0.5 ML-ADJUVANT CPG 1018 (PF) IM SYRINGE source file | $97.73 | $206.61 | $52.07–$364.46 | 53% |
| Harris Health lowest Taub Loop Houston, TX · (713) 873-2000 HEPATITIS B VACCINE 20 MCG/0.5 ML-ADJUVANT CPG 1018 (PF) IM SYRINGE source file | $97.73 | $206.61 | $52.07–$364.46 | 53% |
| Harris Health Houston, TX · (713) 873-2000 ECHG HEPLISAV-B 0.5ML VACCINE source file | $111.16 | $235.00 | $59.22–$364.46 | 53% |
| Harris Health Taub Loop Houston, TX · (713) 873-2000 ECHG HEPLISAV-B 0.5ML VACCINE source file | $111.16 | $235.00 | $59.22–$364.46 | 53% |
| St Luke's Lakeside Hospital The Woodlands, TX · (936) 266-4055 HEPATITIS B VACCINE 20 MCG/0.5 ML SYRG 0.5 ML SYRINGE File of Feb 28, 2026 · source file | $195.39 | $558.23 | $44.22–$558.23 | 65% |
| St Luke's Sugar Land Hospital Sugar Land, TX · (281) 637-7000 HEPATITIS B VACCINE 20 MCG/0.5 ML SYRG 0.5 ML SYRINGE File of Feb 28, 2026 · source file | $195.39 | $558.23 | $89.32–$616.85 | 65% |
| St. Lukes Hospital at the Vintage Houston, TX · (832) 534-5000 HEPATITIS B VACCINE 20 MCG/0.5 ML SYRG 0.5 ML SYRINGE File of Feb 28, 2026 · source file | $195.39 | $558.23 | $36.18–$558.23 | 65% |
| CHI St. Luke's Health Springwood Village Spring, TX · (936) 266-4050 HEPATITIS B VACCINE 20 MCG/0.5 ML SYRG 0.5 ML SYRINGE File of Feb 28, 2026 · source file | $195.39 | $558.23 | $44.22–$558.23 | 65% |
| CHI St. Luke's Health Baylor College of Medicine Medical Center Houston, TX · (832) 355-1000 HEPATITIS B VACCINE 20 MCG/0.5 ML SYRG 0.5 ML SYRINGE File of Feb 28, 2026 · source file | $195.39 | $558.23 | $64.31–$558.23 | 65% |
| St Luke's the Woodlands Hospital The Woodlands, TX · (936) 266-4050 HEPATITIS B VACCINE 20 MCG/0.5 ML SYRG 0.5 ML SYRINGE File of Feb 28, 2026 · source file | $195.39 | $558.23 | $44.22–$558.23 | 65% |
| HCA Houston Healthcare Clear Lake Friendswood, TX · (281) 332-2511 HEPB VAC CPG ADULT IM+1 more line at this price File of Sep 1, 2026 · source file | $627.10 | $627.10 | $37.63–$564.39 | — |
Outpatient: lowest $97.73, median $195.39, highest $627.10 — a 6.4× difference within the same market.
As an inpatient, the same code is billed by 8 facilities here, median $195.39. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 8 of 9 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
Heplisav-B is a hepatitis B vaccine for adults that needs only two doses, one month apart, instead of three over six months.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).