RSV antibody shot (100 mg dose) cost in Chicago, IL — inpatient
In Chicago-Naperville-Elgin, IL-IN, 15 hospitals list a cash price for RSV antibody shot for infants and toddlers, larger dose (1 mL, 100 mg) as an inpatient: from $270.94 to $1,635.02, with a median of $536.78. The lowest listed price is at MacNeal Hospital and 1 other hospital — $265.84 less than the median here. Across Illinois, the median is $856.89 at 40 hospitals.
Cash prices at 15 facilities across 11 cities for code 90381, as an inpatient (admitted to hospital) . Collected Sep 27, 2026; the hospital files themselves were last updated between Jan 1, 2025 and Apr 1, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Chicago-Naperville-Elgin, IL-IN.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list |
|---|---|---|---|---|
| MacNeal Hospital lowest Berwyn, IL · (708) 783-9100 Rsv (Nirsevimab / Beyfortus) 100mg/1.0ml Im (Fc) File of Mar 31, 2026 · source file | $270.94 | $1,426.00 | $270.94–$1,975.01 | 81% |
| Gottlieb Memorial Hospital lowest Melrose Park, IL · (708) 681-3200 Rsv (Nirsevimab / Beyfortus) 100mg/1.0ml Im (Fc)+1 more line at this price File of Mar 31, 2026 · source file | $270.94 | $1,426.00 | $429.23–$1,194.99 | 81% |
| Uchicago Medicine AdventHealth Hinsdale Hinsdale, IL · (630) 856-9000 NIRSEVIMAB-ALIP 100 MG/ML INTRAMUSCULAR SYRINGE File of Apr 1, 2026 · source file | $304.20 | $507.00 | — | 40% |
| Loyola University Medical Center Maywood, IL · (708) 216-9000 Rsv (Nirsevimab / Beyfortus) 100mg/1.0ml Im (Fc) File of Mar 31, 2026 · source file | $327.98 | $1,426.00 | $494.82–$1,503.00 | 77% |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Beyfortus: 5 Syringe In 1 Carton (49281-574-15) / 1 Ml In 1 Syringe+3 more lines at this price File of Apr 1, 2026 · source file | $507.00 | $507.00 | — | — |
| Endeavor Health Highland Park Hospital Highland Park, IL Beyfortus: 5 Syringe In 1 Carton (49281-574-15) / 1 Ml In 1 Syringe File of Apr 1, 2026 · source file | $536.78 | $536.78 | — | — |
| Swedish Covenant Health Chicago, IL · (773) 878-8200 Beyfortus: 5 Syringe In 1 Carton (49281-574-15) / 1 Ml In 1 Syringe File of Apr 1, 2026 · source file | $536.78 | $536.78 | — | — |
| Northshore University Healthsystem - Evanston Hospital Evanston, IL · (847) 570-2000 Beyfortus: 5 Syringe In 1 Carton (49281-574-15) / 1 Ml In 1 Syringe File of Apr 1, 2026 · source file | $536.78 | $536.78 | — | — |
| La Rabida Children's Hospital Chicago, IL · (773) 363-6700 BEYFORTUS; RSV; MONO; 1ML DOSE File of Apr 1, 2026 · source file | $613.60 | $613.60 | — | — |
| Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, IL · (312) 227-4000 NIRSEVIMAB-ALIP 100 MG/ML INTRAMUSCULAR SYRINGE File of Apr 1, 2026 · source file | $652.69 | $932.41 | $344.99–$3,678.00 | 30% |
| NorthShore University HealthSystems Glenbrook Hospital Glenview, IL Rsv Monocolonal Ab Seasonal 1 Ml Dose Im Use File of Jan 1, 2025 · source file | $804.70 | $1,238.00 | $201.79–$662.33 | 35% |
| NorthShore University HealthSystems Skokie Hospital Skokie, IL Rsv Monocolonal Ab Seasonal 1 Ml Dose Im Use File of Jan 1, 2025 · source file | $804.70 | $1,238.00 | $201.79–$662.33 | 35% |
| Northshore University Healthsystem - Evanston Hospital Evanston, IL · (847) 570-2000 RSV MONOCOLONAL AB SEASONAL 1 ML DOSE IM USE File of Apr 1, 2026 · source file | $1,238.00 | $1,238.00 | — | — |
| Endeavor Health Highland Park Hospital Highland Park, IL RSV MONOCOLONAL AB SEASONAL 1 ML DOSE IM USE File of Apr 1, 2026 · source file | $1,238.00 | $1,238.00 | — | — |
| Swedish Covenant Health Chicago, IL · (773) 878-8200 RSV MONOCOLONAL AB SEASONAL 1 ML DOSE IM USE File of Apr 1, 2026 · source file | $1,238.00 | $1,238.00 | — | — |
| Edward Hospital Naperville, IL · (630) 527-3000 HC RSV MONOCLONAL AB SEASONAL 1 ML DOSE IM USE File of Apr 1, 2026 · source file | $1,275.00 | $1,275.00 | — | — |
| Elmhurst Memorial Hospital Elmhurst, IL · (331) 221-1000 HC RSV MONOCLONAL AB SEASONAL 1 ML DOSE IM USE File of Apr 1, 2026 · source file | $1,275.00 | $1,275.00 | — | — |
| Swedish Covenant Health Chicago, IL · (773) 878-8200 Beyfortus: 1 Syringe In 1 Carton (49281-574-88) / 1 Ml In 1 Syringe File of Apr 1, 2026 · source file | $1,477.46 | $1,477.46 | — | — |
| Endeavor Health Highland Park Hospital Highland Park, IL Beyfortus: 1 Syringe In 1 Carton (49281-574-88) / 1 Ml In 1 Syringe File of Apr 1, 2026 · source file | $1,477.46 | $1,477.46 | — | — |
| Northshore University Healthsystem - Evanston Hospital Evanston, IL · (847) 570-2000 Beyfortus: 1 Syringe In 1 Carton (49281-574-88) / 1 Ml In 1 Syringe File of Apr 1, 2026 · source file | $1,477.46 | $1,477.46 | — | — |
| NorthShore University HealthSystems Skokie Hospital Skokie, IL NIRSEVIMAB-ALIP 100 MG/ML IM SOSY File of Jan 1, 2025 · source file | $1,478.15 | $2,274.08 | $370.68–$1,216.63 | 35% |
| NorthShore University HealthSystems Glenbrook Hospital Glenview, IL NIRSEVIMAB-ALIP 100 MG/ML IM SOSY File of Jan 1, 2025 · source file | $1,478.15 | $2,274.08 | $370.68–$1,216.63 | 35% |
| Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, IL · (312) 227-4000 H RSV MONOCLONAL ANTIBODY 1 ML FOR IM USE File of Apr 1, 2026 · source file | $1,539.24 | $2,198.91 | $813.60–$3,678.00 | 30% |
| John H. Stroger, Jr. Hospital Chicago, IL · (312) 864-6000 NIRSEVIMAB (CVX 307) ALIP PRESERVATIVE-FREE 100 MG/ML SOL File of Apr 1, 2026 · source file | $1,635.02 | $2,335.75 | $656.23–$1,868.60 | 30% |
Inpatient: lowest $270.94, median $536.78, highest $1,635.02 — a 6.0× difference within the same market.
As an outpatient, the same code is billed by 27 facilities here, median $804.70 — that is the price to compare if you are not being admitted.
Cash or insurance?
At 5 of 7 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at 2 it is below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
This is the larger dose (100 mg) of nirsevimab (Beyfortus), an antibody shot that protects infants from severe RSV. Babies weighing 5 kg (11 lb) or more in their first RSV season get this dose, and high-risk toddlers get two of them in their second season.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).