RSV antibody shot (100 mg dose) cost in Chicago, IL
In Chicago-Naperville-Elgin, IL-IN, 27 hospitals list a cash price for RSV antibody shot for infants and toddlers, larger dose (1 mL, 100 mg): from $116.13 to $3,794.35, with a median of $804.70. The lowest listed price is at Humboldt Park Health — $688.57 less than the median here. Across Illinois, the median is $856.89 at 40 hospitals.
Cash prices at 27 facilities across 21 cities for code 90381, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 27, 2026; the hospital files themselves were last updated between Mar 31, 2026 and Aug 24, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Chicago-Naperville-Elgin, IL-IN.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list | File date |
|---|---|---|---|---|---|
| Humboldt Park Health lowest Chicago, IL · (773) 292-8200 Respiratory syncytial virus antibody, 1.0 mL dosage for injection into muscle | $116.13 | $414.75 | $414.75 | 72% | Aug 24, 2026 source file |
| MacNeal Hospital Berwyn, IL · (708) 783-9100 Rsv (Nirsevimab / Beyfortus) 100mg/1.0ml Im (Fc) | $270.94 | $1,426.00 | $270.94–$1,975.01 | 81% | Mar 31, 2026 source file |
| Gottlieb Memorial Hospital Melrose Park, IL · (708) 681-3200 Rsv (Nirsevimab / Beyfortus) 100mg/1.0ml Im (Fc) | $270.94 | $1,426.00 | $429.23–$1,194.99 | 81% | Mar 31, 2026 source file |
| Gottlieb Memorial Hospital Melrose Park, IL · (708) 681-3200 Rsv (Nirsevimab / Beyfortus) 100mg/1.0ml Im (Fc) | $270.94 | $1,426.00 | $429.23–$1,194.99 | 81% | Mar 31, 2026 source file |
| Uchicago Medicine AdventHealth Hinsdale Hinsdale, IL · (630) 856-9000 NIRSEVIMAB-ALIP 100 MG/ML INTRAMUSCULAR SYRINGE | $304.20 | $507.00 | — | 40% | Apr 1, 2026 source file |
| Loyola University Medical Center Maywood, IL · (708) 216-9000 Rsv (Nirsevimab / Beyfortus) 100mg/1.0ml Im (Fc) | $327.98 | $1,426.00 | $494.82–$1,503.00 | 77% | Mar 31, 2026 source file |
| Loyola University Medical Center Maywood, IL · (708) 216-9000 Rsv (Nirsevimab / Beyfortus) 100mg/1.0ml Im (Fc) | $327.98 | $1,426.00 | $1,363.22 | 77% | Mar 31, 2026 source file |
| Morris Hospital Morris, IL · (815) 942-2932 Respiratory syncytial virus antibody, 1.0 mL dosage for injection into muscle | $416.00 | $1,729.00 | $587.86–$1,469.65 | 76% | Jun 30, 2026 source file |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Beyfortus: 1 Syringe In 1 Carton (49281-575-00) / .5 Ml In 1 Syringe | $507.00 | $507.00 | — | — | Apr 1, 2026 source file |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Beyfortus: 5 Syringe In 1 Carton (49281-574-15) / 1 Ml In 1 Syringe | $507.00 | $507.00 | — | — | Apr 1, 2026 source file |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Pr Rsv Monoclonal Antb Seasonal Dose 1 Ml Im Use | $507.00 | $507.00 | — | — | Apr 1, 2026 source file |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Beyfortus: 1 Syringe In 1 Carton (49281-574-88) / 1 Ml In 1 Syringe | $507.00 | $507.00 | — | — | Apr 1, 2026 source file |
| Endeavor Health Highland Park Hospital Highland Park, IL Beyfortus: 5 Syringe In 1 Carton (49281-574-15) / 1 Ml In 1 Syringe | $536.78 | $536.78 | — | — | Apr 1, 2026 source file |
| Swedish Covenant Health Chicago, IL · (773) 878-8200 Beyfortus: 5 Syringe In 1 Carton (49281-574-15) / 1 Ml In 1 Syringe | $536.78 | $536.78 | — | — | Apr 1, 2026 source file |
| Northshore University Healthsystem - Evanston Hospital Evanston, IL · (847) 570-2000 Beyfortus: 5 Syringe In 1 Carton (49281-574-15) / 1 Ml In 1 Syringe | $536.78 | $536.78 | — | — | Apr 1, 2026 source file |
| La Rabida Children's Hospital Chicago, IL · (773) 363-6700 BEYFORTUS; RSV; MONO; 1ML DOSE | $613.60 | $613.60 | — | — | Apr 1, 2026 source file |
| Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, IL · (312) 227-4000 NIRSEVIMAB-ALIP 100 MG/ML INTRAMUSCULAR SYRINGE | $652.69 | $932.41 | $158.51–$8,500.00 | 30% | — source file |
| NorthShore University HealthSystems Skokie Hospital Skokie, IL Rsv Monocolonal Ab Seasonal 1 Ml Dose Im Use | $804.70 | $1,238.00 | $167.13–$675.95 | 35% | — source file |
| NorthShore University HealthSystems Glenbrook Hospital Glenview, IL Rsv Monocolonal Ab Seasonal 1 Ml Dose Im Use | $804.70 | $1,238.00 | $167.13–$675.95 | 35% | — source file |
| The Methodist Hospitals Gary, IN · (219) 886-4000 NIRSEVIMAB-ALIP 100 MG/ML IM SOSY [184384] | $1,052.66 | $1,503.80 | $0.01–$1,338.38 | 30% | — source file |
| Methodist Hospital-Southlake Merrillville, IN · (219) 886-4000 NIRSEVIMAB-ALIP 100 MG/ML IM SOSY [184384] | $1,052.66 | $1,503.80 | $0.01–$1,338.38 | 30% | — source file |
| Northshore University Healthsystem - Evanston Hospital Evanston, IL · (847) 570-2000 RSV MONOCOLONAL AB SEASONAL 1 ML DOSE IM USE | $1,238.00 | $1,238.00 | — | — | Apr 1, 2026 source file |
| Endeavor Health Highland Park Hospital Highland Park, IL RSV MONOCOLONAL AB SEASONAL 1 ML DOSE IM USE | $1,238.00 | $1,238.00 | — | — | Apr 1, 2026 source file |
| Swedish Covenant Health Chicago, IL · (773) 878-8200 RSV MONOCOLONAL AB SEASONAL 1 ML DOSE IM USE | $1,238.00 | $1,238.00 | — | — | Apr 1, 2026 source file |
| Edward Hospital Naperville, IL · (630) 527-3000 HC RSV MONOCLONAL AB SEASONAL 1 ML DOSE IM USE | $1,275.00 | $1,275.00 | — | — | Apr 1, 2026 source file |
| Elmhurst Memorial Hospital Elmhurst, IL · (331) 221-1000 HC RSV MONOCLONAL AB SEASONAL 1 ML DOSE IM USE | $1,275.00 | $1,275.00 | — | — | Apr 1, 2026 source file |
| Northshore University Healthsystem - Evanston Hospital Evanston, IL · (847) 570-2000 Beyfortus: 1 Syringe In 1 Carton (49281-574-88) / 1 Ml In 1 Syringe | $1,477.46 | $1,477.46 | — | — | Apr 1, 2026 source file |
| Endeavor Health Highland Park Hospital Highland Park, IL Beyfortus: 1 Syringe In 1 Carton (49281-574-88) / 1 Ml In 1 Syringe | $1,477.46 | $1,477.46 | — | — | Apr 1, 2026 source file |
| Swedish Covenant Health Chicago, IL · (773) 878-8200 Beyfortus: 1 Syringe In 1 Carton (49281-574-88) / 1 Ml In 1 Syringe | $1,477.46 | $1,477.46 | — | — | Apr 1, 2026 source file |
| NorthShore University HealthSystems Skokie Hospital Skokie, IL NIRSEVIMAB-ALIP 100 MG/ML IM SOSY | $1,478.15 | $2,274.08 | $307.00–$1,241.65 | 35% | — source file |
| NorthShore University HealthSystems Glenbrook Hospital Glenview, IL NIRSEVIMAB-ALIP 100 MG/ML IM SOSY | $1,478.15 | $2,274.08 | $307.00–$1,241.65 | 35% | — source file |
| Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, IL · (312) 227-4000 H RSV MONOCLONAL ANTIBODY 1 ML FOR IM USE | $1,539.24 | $2,198.91 | $373.81–$8,500.00 | 30% | — source file |
| John H. Stroger, Jr. Hospital Chicago, IL · (312) 864-6000 NIRSEVIMAB (CVX 307) ALIP PRESERVATIVE-FREE 100 MG/ML SOL | $1,635.02 | $2,335.75 | $656.23–$1,868.60 | 30% | — source file |
| Palos Community Hospital Palos Heights, IL · (708) 923-4000 NIRSEVIMAB-ALIP 100 MG/ML IM SYRG | $1,828.57 | $2,612.25 | $417.96–$2,612.25 | 30% | Apr 1, 2026 source file |
| Northwestern Medicine McHenry Hospital McHenry, IL · (815) 344-5000 NIRSEVIMAB-ALIP 100 MG/ML IM SYRG | $2,094.57 | $2,992.25 | $577.50–$2,992.25 | 30% | Apr 1, 2026 source file |
| Northwestern Medicine Delnor Hospital Geneva, IL · (630) 208-3000 NIRSEVIMAB-ALIP 100 MG/ML IM SYRG | $2,458.40 | $3,512.00 | $523.29–$3,512.00 | 30% | Apr 1, 2026 source file |
| Northwestern Memorial Hospital Chicago, IL · (312) 926-2000 NIRSEVIMAB-ALIP 100 MG/ML IM SYRG | $2,458.40 | $3,512.00 | $514.63–$5,420.50 | 30% | Apr 1, 2026 source file |
| Northwestern Medicine Valley West Hospital Sandwich, IL · (815) 786-8484 NIRSEVIMAB-ALIP 100 MG/ML IM SYRG | $2,464.17 | $3,520.25 | $242.90–$3,520.25 | 30% | Apr 1, 2026 source file |
| Northwestern Lake Forest Hospital Lake Forest, IL · (847) 234-5600 NIRSEVIMAB-ALIP 100 MG/ML IM SYRG | $2,586.50 | $3,695.00 | $613.37–$3,695.00 | 30% | Apr 1, 2026 source file |
| Northwestern Medicine Kishwaukee Hospital DeKalb, IL · (815) 756-1521 NIRSEVIMAB-ALIP 100 MG/ML IM SYRG | $3,098.37 | $4,426.25 | $810.00–$4,426.25 | 30% | Apr 1, 2026 source file |
| Northwestern Medicine Central DuPage Hospital Winfield, IL · (630) 682-1600 NIRSEVIMAB-ALIP 100 MG/ML IM SYRG | $3,794.35 | $5,420.50 | $374.01–$5,420.50 | 30% | Apr 1, 2026 source file |
Outpatient: lowest $116.13, median $804.70, highest $3,794.35 — a 32.7× difference within the same market.
As an inpatient, the same code is billed by 15 facilities here, median $536.78. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 17 of 19 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at 4 it is below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
This is the larger dose (100 mg) of nirsevimab (Beyfortus), an antibody shot that protects infants from severe RSV. Babies weighing 5 kg (11 lb) or more in their first RSV season get this dose, and high-risk toddlers get two of them in their second season.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).