AFP test cost in McAllen, TX
In McAllen-Edinburg-Mission, TX, 4 hospitals list a cash price for alpha-fetoprotein (AFP) blood test: from $16.00 to $1,816.53, with a median of $52.16. The lowest listed price is at Knapp Medical Center and 1 other hospital — $36.16 less than the median here. Across Texas, the median is $122.60 at 292 hospitals.
Cash prices at 4 facilities across 4 cities for code 82105, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 27, 2026; the hospital files themselves were last updated between Oct 6, 2025 and Sep 1, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in McAllen-Edinburg-Mission, TX.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list |
|---|---|---|---|---|
| Knapp Medical Center lowest Weslaco, TX · (956) 968-8567 Hc Alpha-Fetoprotein, Serum File of Sep 1, 2026 · source file | $16.00 | $220.50 | $11.74–$216.09 | 93% |
| Mission Regional Medical Center lowest Mission, TX · (956) 323-9000 AFP MATERNAL SCREEN I+1 more line at this price File of Sep 1, 2026 · source file | $16.00 | $155.14 | $14.06–$124.11 | 90% |
| Driscoll Children's Hospital Rio Grande Valley Edinburg, TX · (361) 694-5041 Alpha-Fetoprotein, Serum File of Oct 6, 2025 · source file | $88.32 | $441.60 | $14.09–$165.82 | 80% |
| Rio Grande Regional Hospital San Juan, TX · (956) 632-6000 Alpha-fetoprotein (AFP); serum +1 more line at this price File of Sep 1, 2026 · source file | $1,816.53 | $1,816.53 | $14.37–$1,544.05 | — |
Outpatient: lowest $16.00, median $52.16, highest $1,816.53 — a 113.5× difference within the same market.
Cash or insurance?
At 3 of 4 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
An AFP test measures a protein made by the liver and by a developing baby. In adults it is used to watch for liver cancer in people with cirrhosis and to follow some testicular cancers.
What the price covers
The price usually covers running the test. The blood draw (36415) is often billed as a separate line.