AFP test cost in San Antonio, TX
In San Antonio-New Braunfels, TX, 16 hospitals list a cash price for alpha-fetoprotein (AFP) blood test: from $38.50 to $1,110.07, with a median of $1,110.07. The lowest listed price is at University Health System — $1,071.57 less than the median here. Across Texas, the median is $122.60 at 292 hospitals.
Cash prices at 16 facilities across 5 cities for code 82105, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 29, 2026; the hospital files themselves were last updated between Oct 14, 2025 and Sep 1, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in San Antonio-New Braunfels, TX.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list | File date |
|---|---|---|---|---|---|
| University Health System lowest San Antonio, TX · (210) 358-2000 HC ALPHA-FETOPROTEIN, SERUM - ALPHA FETOPROTEIN, M | $38.50 | $154.00 | $14.09–$385.00 | 75% | Oct 14, 2025 source file |
| University Health System lowest San Antonio, TX · (210) 358-2000 HC ALPHA-FETOPROTEIN, SERUM - ALPHA-FETOPROTEIN MA | $38.50 | $154.00 | $14.09–$385.00 | 75% | Oct 14, 2025 source file |
| Medina Regional Hospital Hondo, TX · (830) 426-7700 ALPHA-FETOPROTEIN SERUM | $42.85 | $47.61 | $11.43–$76.21 | 10% | Jul 29, 2026 source file |
| Guadalupe Regional Medical Center Seguin, TX · (830) 379-2411 ALPHA-FETOPROTEIN;SERUM | $68.00 | $136.00 | $16.77–$136.00 | 50% | — source file |
| Santa Rosa Hospital - Westover Hills San Antonio, TX · (210) 703-8211 HC 82105 AFP, TUMOR MARKER | $74.58 | $226.00 | $6.12–$214.70 | 67% | Jan 13, 2026 source file |
| Guadalupe Regional Medical Center Seguin, TX · (830) 379-2411 ALPHA-FETOPROTEIN(AFP);SERUM | $76.50 | $153.00 | $16.77–$153.00 | 50% | — source file |
| Santa Rosa Hospital - Westover Hills San Antonio, TX · (210) 703-8211 HC 82105 ALPHA-FETOPROTEIN, SERUM | $79.86 | $242.00 | $6.12–$229.90 | 67% | Jan 13, 2026 source file |
| Santa Rosa Hospital - Westover Hills San Antonio, TX · (210) 703-8211 HC 82105 AFP (TRI TEST) | $79.86 | $242.00 | $6.12–$229.90 | 67% | Jan 13, 2026 source file |
| Guadalupe Regional Medical Center Seguin, TX · (830) 379-2411 ALPHA-FETOPROTEIN:SERUM | $90.00 | $180.00 | $16.77–$180.00 | 50% | — source file |
| Medina Regional Hospital Hondo, TX · (830) 426-7700 ALPHA-FETOPROTEIN TUMOR MARKER | $90.06 | $100.06 | $24.01–$100.06 | 10% | Jul 29, 2026 source file |
| Medina Regional Hospital Hondo, TX · (830) 426-7700 MATERNAL SERUM SCREEN | $90.06 | $100.06 | $24.01–$100.06 | 10% | Jul 29, 2026 source file |
| Guadalupe Regional Medical Center Seguin, TX · (830) 379-2411 ALPHA-FETOPROTEIN:SERUM E/3092 | $101.50 | $203.00 | $16.77–$203.00 | 50% | — source file |
| Medina Regional Hospital Hondo, TX · (830) 426-7700 AFP TETRA | $228.23 | $253.58 | $26.83–$253.58 | 10% | Jul 29, 2026 source file |
| Warm Springs Rehabilitation Hospital of San Antonio San Antonio, TX Alpha-Fetoprotein Serum | $247.85 | $247.85 | $11.74–$223.07 | — | Aug 6, 2026 source file |
| Methodist Specialty and Transplant San Antonio, TX · (210) 575-4000 ALPHA FETOPROT SERUM MAT | $1,110.07 | $1,110.07 | $55.50–$1,110.07 | — | Sep 1, 2026 source file |
| Methodist Specialty and Transplant San Antonio, TX · (210) 575-4000 ALPHA FETOPROT SERUM | $1,110.07 | $1,110.07 | $543.93 | — | Sep 1, 2026 source file |
| Methodist Hospital Helotes, TX · (210) 575-4000 ALPHA FETOPROT SERUM MAT | $1,110.07 | $1,110.07 | $55.50–$1,110.07 | — | Sep 1, 2026 source file |
| Methodist Hospital Helotes, TX · (210) 575-4000 ALPHA FETOPROT SERUM | $1,110.07 | $1,110.07 | $55.50–$1,110.07 | — | Sep 1, 2026 source file |
| Methodist Hospital Landmark San Antonio, TX · (210) 638-2101 ALPHA FETOPROT SERUM | $1,110.07 | $1,110.07 | $273.08–$943.56 | — | Sep 1, 2026 source file |
| Methodist Hospital Westover Hills San Antonio, TX · (210) 638-2101 ALPHA FETOPROT SERUM MAT | $1,110.07 | $1,110.07 | $273.08–$943.56 | — | Sep 1, 2026 source file |
| Methodist Hospital Westover Hills San Antonio, TX · (210) 638-2101 ALPHA FETOPROT SERUM | $1,110.07 | $1,110.07 | $273.08–$943.56 | — | Sep 1, 2026 source file |
| Methodist Hospital Atascosa Jourdanton, TX · (830) 769-3515 ALPHA FETOPROT SERUM | $1,110.07 | $1,110.07 | $55.50–$943.56 | — | Sep 1, 2026 source file |
| Methodist Hospital Atascosa Jourdanton, TX · (830) 769-3515 ALPHA FETOPROT SERUM MAT | $1,110.07 | $1,110.07 | $55.50–$943.56 | — | Sep 1, 2026 source file |
| Methodist Hospital Stone Oak San Antonio, TX · (210) 638-2101 ALPHA FETOPROT SERUM | $1,110.07 | $1,110.07 | $55.50–$943.56 | — | Sep 1, 2026 source file |
| Methodist Hospital Stone Oak San Antonio, TX · (210) 638-2101 ALPHA FETOPROT SERUM MAT | $1,110.07 | $1,110.07 | $55.50–$943.56 | — | Sep 1, 2026 source file |
| Methodist Texsan Hospital Rehab San Antonio, TX ALPHA FETOPROT SERUM MAT | $1,110.07 | $1,110.07 | $55.50–$943.56 | — | Sep 1, 2026 source file |
| Methodist Texsan Hospital Rehab San Antonio, TX ALPHA FETOPROT SERUM | $1,110.07 | $1,110.07 | $55.50–$943.56 | — | Sep 1, 2026 source file |
| Metropolitan Methodist San Antonio, TX · (210) 575-4000 ALPHA FETOPROT SERUM | $1,110.07 | $1,110.07 | $55.50–$943.56 | — | Sep 1, 2026 source file |
| Metropolitan Methodist San Antonio, TX · (210) 575-4000 ALPHA FETOPROT SERUM MAT | $1,110.07 | $1,110.07 | $55.50–$943.56 | — | Sep 1, 2026 source file |
| Stone Oak Rehab San Antonio, TX ALPHA FETOPROT SERUM | $1,110.07 | $1,110.07 | $55.50–$943.56 | — | Sep 1, 2026 source file |
| Stone Oak Rehab San Antonio, TX ALPHA FETOPROT SERUM MAT | $1,110.07 | $1,110.07 | $55.50–$943.56 | — | Sep 1, 2026 source file |
| Northeast Methodist San Antonio, TX · (210) 638-2101 ALPHA FETOPROT SERUM MAT | $1,110.07 | $1,110.07 | $55.50–$943.56 | — | Sep 1, 2026 source file |
| Northeast Methodist San Antonio, TX · (210) 638-2101 ALPHA FETOPROT SERUM | $1,110.07 | $1,110.07 | $55.50–$943.56 | — | Sep 1, 2026 source file |
| Methodist Hospital Landmark San Antonio, TX · (210) 638-2101 Alpha-fetoprotein (AFP); serum | $1,110.07 | $1,110.07 | $14.09 | — | Sep 1, 2026 source file |
| Methodist Texsan Hospital San Antonio, TX · (210) 638-2101 ALPHA FETOPROT SERUM | $1,110.07 | $1,110.07 | $55.50–$943.56 | — | Sep 1, 2026 source file |
| Methodist Texsan Hospital San Antonio, TX · (210) 638-2101 ALPHA FETOPROT SERUM MAT | $1,110.07 | $1,110.07 | $55.50–$943.56 | — | Sep 1, 2026 source file |
Outpatient: lowest $38.50, median $1,110.07, highest $1,110.07 — a 28.8× difference within the same market.
As an inpatient, the same code is billed by 5 facilities here, median $68.00. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 4 of 16 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
An AFP test measures a protein made by the liver and by a developing baby. In adults it is used to watch for liver cancer in people with cirrhosis and to follow some testicular cancers.
What the price covers
The price usually covers running the test. The blood draw (36415) is often billed as a separate line.