Hepatitis B vaccine (Heplisav-B) cost in Cleveland, OH
In Cleveland, OH, 24 hospitals list a cash price for hepatitis B vaccine, adult, 2-dose schedule (Heplisav-B): from $105.00 to $728.91, with a median of $234.48. The lowest listed price is at Ashtabula County Medical Center — $129.48 less than the median here. Across Ohio, the median is $218.74 at 56 hospitals.
Cash prices at 24 facilities across 18 cities for code 90739, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 29, 2026; the hospital files themselves were last updated between Apr 1, 2026 and Sep 8, 2026.
Lowest$105.00Ashtabula County Medical Center
Median$234.48half of hospitals charge less
Highest$728.91in this market
Difference6.9×highest vs lowest
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Cleveland, OH.
median
Lowest $105.00Highest $728.91
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list |
|---|---|---|---|---|
| Ashtabula County Medical Center lowest Ashtabula, OH · (440) 997-2262 HEPB VACC 2 DOSE ADULT IM File of Sep 8, 2026 · source file | $105.00 | $150.00 | $60.00–$408.42 | 30% |
| University Hospitals Conneaut Medical Center Conneaut, OH · (440) 593-1131 HC HEPB VACCINE ADULT 2/4 DOSE SCHEDULE FOR IM USE File of Jul 14, 2026 · source file | $109.50 | $146.00 | $45.26–$757.61 | 25% |
| Uhhs Memorial Hospital of Geneva Geneva, OH · (440) 415-0151 HC HEPB VACCINE ADULT 2/4 DOSE SCHEDULE FOR IM USE File of Jul 14, 2026 · source file | $109.50 | $146.00 | $29.20–$700.79 | 25% |
| Metrohealth System Cleveland, OH · (216) 778-7089 Heplisav-B: 5 Syringe In 1 Carton (50090-4526-0) / .5 Ml In 1 Syringe (50090-4526-1) File of Apr 1, 2026 · source file | $116.90 | $334.00 | — | 65% |
| UH Regional Hospitals Chardon, OH · (440) 285-6246 HC HEPB VACCINE ADULT 2/4 DOSE SCHEDULE FOR IM USE File of Jul 14, 2026 · source file | $118.50 | $158.00 | $41.24–$621.43 | 25% |
| UH Cleveland Medical Center Cleveland, OH · (216) 844-1000 HC HEPB VACCINE ADULT 2/4 DOSE SCHEDULE FOR IM USE+1 more line at this price File of Jul 14, 2026 · source file | $118.50 | $158.00 | $42.66–$1,442.52 | 25% |
| UH St John Medical Center Westlake, OH · (440) 835-8000 HC HEPB VACCINE ADULT 2/4 DOSE SCHEDULE FOR IM USE File of Jul 14, 2026 · source file | $118.50 | $158.00 | $38.71–$556.05 | 25% |
| Parma Community General Hospital Parma, OH · (440) 743-3000 HC HEPB VACCINE ADULT 2/4 DOSE SCHEDULE FOR IM USE File of Jul 14, 2026 · source file | $118.50 | $158.00 | $48.03–$412.27 | 25% |
| University Hospitals Beachwood Medical Center Beachwood, OH · (216) 545-4800 HC HEPB VACCINE ADULT 2/4 DOSE SCHEDULE FOR IM USE File of Jul 14, 2026 · source file | $118.50 | $158.00 | $63.20–$319.60 | 25% |
| University Hospitals Ahuja Medical Center Beachwood, OH · (216) 593-5511 HC HEPB VACCINE ADULT 2/4 DOSE SCHEDULE FOR IM USE File of Jul 14, 2026 · source file | $118.50 | $158.00 | $34.92–$489.51 | 25% |
| Lake West Hospital Willoughby, OH · (440) 953-9600 HC HEPB VACCINE ADULT 2/4 DOSE SCHEDULE FOR IM USE File of Jul 14, 2026 · source file | $118.50 | $158.00 | $63.20–$319.60 | 25% |
| University Hospitals - Elyria Medical Center Elyria, OH · (440) 329-7500 HC HEPB VACCINE ADULT 2/4 DOSE SCHEDULE FOR IM USE File of Jul 14, 2026 · source file | $118.50 | $158.00 | $56.56–$423.10 | 25% |
| Metrohealth System Cleveland, OH · (216) 778-7089 Engerix-B: 10 Syringe In 1 Carton (58160-821-52) / 1 Ml In 1 Syringe (58160-821-43)+1 more line at this price File of Apr 1, 2026 · source file | $123.90 | $354.00 | — | 65% |
| Metrohealth System Cleveland, OH · (216) 778-7089 NDC Description Not Available File of Apr 1, 2026 · source file | $137.31 | $392.32 | — | 65% |
| Metrohealth System Cleveland, OH · (216) 778-7089 Heplisav-B: 5 Syringe In 1 Carton (43528-003-05) / .5 Ml In 1 Syringe (43528-003-01) File of Apr 1, 2026 · source file | $137.39 | $392.54 | — | 65% |
| Metrohealth System Cleveland, OH · (216) 778-7089 HEPATITIS B VAC RECOMB ADJ 20 MCG/0.5ML IM SOSY [149467] File of Apr 1, 2026 · source file | $267.80 | $412.00 | — | 35% |
| Mercy Health Regional Medical Center Lorain, OH · (440) 960-4000 HEPATITIS B VAC RECOMB ADJ 20 MCG/0.5ML IM SOSY source file | $350.46 | $584.10 | — | 40% |
| The Cleveland Clinic Foundation Cleveland, OH · (216) 952-9829 HEPB VACC 2 DOSE ADULT IM+1 more line at this price File of Jun 16, 2026 · source file | $365.30 | $562.00 | $122.52–$562.00 | 35% |
| South Pointe Hospital Warrensville Heights, OH · (216) 491-6523 HEPB VACC 2 DOSE ADULT IM+1 more line at this price File of Jun 15, 2026 · source file | $365.30 | $562.00 | $122.52–$562.00 | 35% |
| Lodi Community Hospital Lodi, OH · (330) 948-1222 HEPB VACC 2 DOSE ADULT IM+1 more line at this price File of Jun 15, 2026 · source file | $365.30 | $562.00 | $158.93–$562.00 | 35% |
| Lutheran Hospital Cleveland, OH · (216) 696-4300 HEPB VACC 2 DOSE ADULT IM+1 more line at this price File of Jun 15, 2026 · source file | $365.30 | $562.00 | $122.52–$562.00 | 35% |
| Hillcrest Hospital Mayfield Heights, OH · (440) 312-4500 HEPB VACC 2 DOSE ADULT IM+1 more line at this price File of Jun 15, 2026 · source file | $365.30 | $562.00 | $122.52–$562.00 | 35% |
| Medina Hospital Medina, OH · (330) 725-1000 HEPB VACC 2 DOSE ADULT IM+1 more line at this price File of Jun 15, 2026 · source file | $365.30 | $562.00 | $122.52–$562.00 | 35% |
| Fairview Hospital Cleveland, OH · (216) 476-7000 HEPB VACC 2 DOSE ADULT IM+1 more line at this price File of Jun 15, 2026 · source file | $365.30 | $562.00 | $122.52–$562.00 | 35% |
| Cleveland Clinic Avon Hospital Avon, OH · (440) 695-5000 HEPB VACC 2 DOSE ADULT IM+1 more line at this price File of Jun 15, 2026 · source file | $365.30 | $562.00 | $122.52–$562.00 | 35% |
| Marymount Hospital Garfield Heights, OH · (216) 587-8210 HEPB VACC 2 DOSE ADULT IM+1 more line at this price File of Jun 15, 2026 · source file | $365.30 | $562.00 | $122.52–$562.00 | 35% |
| Euclid Hospital Euclid, OH · (216) 531-9000 HEPB VACC 2 DOSE ADULT IM+1 more line at this price File of Jun 15, 2026 · source file | $365.30 | $562.00 | $122.52–$562.00 | 35% |
| Medina Hospital Medina, OH · (330) 725-1000 HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE+1 more line at this price File of Jun 15, 2026 · source file | $728.91 | $1,121.40 | $244.47–$1,121.40 | 35% |
| Hillcrest Hospital Mayfield Heights, OH · (440) 312-4500 HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE+1 more line at this price File of Jun 15, 2026 · source file | $728.91 | $1,121.40 | $244.47–$1,121.40 | 35% |
| Lodi Community Hospital Lodi, OH · (330) 948-1222 HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE+1 more line at this price File of Jun 15, 2026 · source file | $728.91 | $1,121.40 | $317.13–$1,121.40 | 35% |
| Marymount Hospital Garfield Heights, OH · (216) 587-8210 HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE+1 more line at this price File of Jun 15, 2026 · source file | $728.91 | $1,121.40 | $244.47–$1,121.40 | 35% |
| South Pointe Hospital Warrensville Heights, OH · (216) 491-6523 HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE+1 more line at this price File of Jun 15, 2026 · source file | $728.91 | $1,121.40 | $244.47–$1,121.40 | 35% |
| Cleveland Clinic Children's Hospital for Rehabilitation Cleveland, OH · (216) 448-6400 HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE+1 more line at this price File of Jun 15, 2026 · source file | $728.91 | $1,121.40 | $317.13–$1,121.40 | 35% |
| Cleveland Clinic Avon Hospital Avon, OH · (440) 695-5000 HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE+1 more line at this price File of Jun 15, 2026 · source file | $728.91 | $1,121.40 | $244.47–$1,121.40 | 35% |
| Fairview Hospital Cleveland, OH · (216) 476-7000 HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE+1 more line at this price File of Jun 15, 2026 · source file | $728.91 | $1,121.40 | $244.47–$1,121.40 | 35% |
| Lutheran Hospital Cleveland, OH · (216) 696-4300 HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE+1 more line at this price File of Jun 15, 2026 · source file | $728.91 | $1,121.40 | $244.47–$1,121.40 | 35% |
| Euclid Hospital Euclid, OH · (216) 531-9000 HEPLISAV-B (PF) 20 MCG/0.5 ML INTRAMUSCULAR SYRINGE+1 more line at this price File of Jun 15, 2026 · source file | $728.91 | $1,121.40 | $244.47–$1,121.40 | 35% |
Hospital The hospital that published the price, its city and the line exactly as written in its price file.
Cash price The hospital's own price for a patient paying without insurance (“discounted cash” in its price file). Hospitals must publish it under federal law, 45 CFR 180.50. Call to confirm it before booking. More
List price The hospital's full chargemaster price (“gross charge”) before any discount. Almost nobody pays it; the gap to the cash price shows what the self-pay discount is worth. More
Insurers pay The lowest and highest rates this hospital has agreed with insurance plans for the same item, from its price file. If the cash price is below what your plan pays and you have not met your deductible, paying cash can cost you less. More
Off list How much lower the cash price is than the list price.
Outpatient: lowest $105.00, median $234.48, highest $728.91 — a 6.9× difference within the same market.
As an inpatient, the same code is billed by 25 facilities here, median $187.50. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 22 of 22 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
Heplisav-B is a hepatitis B vaccine for adults that needs only two doses, one month apart, instead of three over six months.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).