RSV vaccine (Abrysvo) cost in Chicago, IL
In Chicago-Naperville-Elgin, IL-IN, 8 hospitals list a cash price for RSV vaccine (Abrysvo), one dose for older adults or during pregnancy: from $86.73 to $2,097.08, with a median of $251.25. The lowest listed price is at Humboldt Park Health — $164.52 less than the median here. Across Illinois, the median is $281.25 at 14 hospitals.
Cash prices at 8 facilities across 6 cities for code 90678, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 23, 2026; the hospital files themselves were last updated between Mar 31, 2026 and Aug 24, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Chicago-Naperville-Elgin, IL-IN.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list | File date |
|---|---|---|---|---|---|
| Humboldt Park Health lowest Chicago, IL · (773) 292-8200 Respiratory syncytial virus vaccine, preF, subunit, bivalent, for intramuscular use | $86.73 | $309.75 | $309.75 | 72% | Aug 24, 2026 source file |
| Gottlieb Memorial Hospital Melrose Park, IL · (708) 681-3200 Rsv Pref (Abrysvo 0.5ml) Age > 60yrs or Gestational Age 32-36 Wk | $161.50 | $850.00 | $255.85–$712.30 | 81% | Mar 31, 2026 source file |
| Gottlieb Memorial Hospital Melrose Park, IL · (708) 681-3200 Rsv Pref (Abrysvo 0.5ml) Age > 60yrs or Gestational Age 32-36 Wk | $161.50 | $850.00 | $255.85–$712.30 | 81% | Mar 31, 2026 source file |
| Uchicago Medicine AdventHealth Hinsdale Hinsdale, IL · (630) 856-9000 RESP SYNCYTIAL VIRUS VAC, PREF A AND B (PF) 120 MCG/0.5 ML IM SOLUTION | $184.20 | $307.00 | — | 40% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth Hinsdale Hinsdale, IL · (630) 856-9000 RESP SYNCYTIAL VIRUS VAC, PREF A AND B (PF) 120 MCG/0.5 ML IM SOLUTION | $184.20 | $307.00 | — | 40% | Apr 1, 2026 source file |
| Loyola University Medical Center Maywood, IL · (708) 216-9000 Rsv Pref (Abrysvo 0.5ml) Age > 60yrs or Gestational Age 32-36 Wk | $195.50 | $850.00 | $36.28 | 77% | Mar 31, 2026 source file |
| Loyola University Medical Center Maywood, IL · (708) 216-9000 Rsv Pref (Abrysvo 0.5ml) Age > 60yrs or Gestational Age 32-36 Wk | $195.50 | $850.00 | $294.95–$895.90 | 77% | Mar 31, 2026 source file |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 NDC Description Not Available | $307.00 | $307.00 | — | — | Apr 1, 2026 source file |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Abrysvo: 1 Tray In 1 Carton (0069-0344-01) / 1 Kit In 1 Tray (0069-0344-21) * .5 Ml In 1 Vial, Glass (0069-0207-01) * .69 Ml In 1 Syringe, Glass (0069-0250-01) | $307.00 | $307.00 | — | — | Apr 1, 2026 source file |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Pr Rsv Vaccine Pref Subunit Bivalent For Im Use | $307.00 | $307.00 | — | — | Apr 1, 2026 source file |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Abrysvo: 5 Tray In 1 Carton (0069-0344-05) / 1 Kit In 1 Tray (0069-0344-21) * .5 Ml In 1 Vial, Glass (0069-0207-01) * .69 Ml In 1 Syringe, Glass (0069-0250-01) | $307.00 | $307.00 | — | — | Apr 1, 2026 source file |
| Elmhurst Memorial Hospital Elmhurst, IL · (331) 221-1000 Abrysvo: 1 Tray In 1 Carton (0069-0344-01) / 1 Kit In 1 Tray (0069-0344-21) * .5 Ml In 1 Vial, Glass (0069-0207-01) * .69 Ml In 1 Syringe, Glass (0069-0250-01) | $2,097.08 | $2,097.08 | — | — | Apr 1, 2026 source file |
| Naperville Psychiatric Ventures Naperville, IL Abrysvo: 1 Tray In 1 Carton (0069-0344-01) / 1 Kit In 1 Tray (0069-0344-21) * .5 Ml In 1 Vial, Glass (0069-0207-01) * .69 Ml In 1 Syringe, Glass (0069-0250-01) | $2,097.08 | $2,097.08 | — | — | Apr 1, 2026 source file |
| Edward Hospital Naperville, IL · (630) 527-3000 Abrysvo: 1 Tray In 1 Carton (0069-0344-01) / 1 Kit In 1 Tray (0069-0344-21) * .5 Ml In 1 Vial, Glass (0069-0207-01) * .69 Ml In 1 Syringe, Glass (0069-0250-01) | $2,097.08 | $2,097.08 | — | — | Apr 1, 2026 source file |
Outpatient: lowest $86.73, median $251.25, highest $2,097.08 — a 24.2× difference within the same market.
As an inpatient, the same code is billed by 7 facilities here, median $307.00. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 2 of 3 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at 2 it is below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
Abrysvo is a single-dose RSV vaccine. The CDC recommends an RSV vaccine for everyone 75 and older and for adults 50 to 74 at higher risk, and Abrysvo is also given in weeks 32 to 36 of pregnancy to protect the newborn.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit).