Hepatitis A and B vaccine (Twinrix) cost in Chicago, IL
In Chicago-Naperville-Elgin, IL-IN, 26 hospitals list a cash price for hepatitis A and B combination vaccine, adult (Twinrix): from $53.74 to $628.34, with a median of $211.64. The lowest listed price is at Loretto Hospital — $157.90 less than the median here. Across Illinois, the median is $203.54 at 39 hospitals.
- The median here, $211.64, is 22% above the US median of $172.95.
- 6 of 26 hospitals list a cash price equal to their full list price, with no self-pay discount.
Cash prices at 26 facilities across 21 cities for code 90636, as an outpatient — the setting a self-pay patient normally buys. Collected Nov 10, 2026; the hospital files themselves were last updated between Jan 1, 2025 and Nov 5, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Chicago-Naperville-Elgin, IL-IN.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list |
|---|---|---|---|---|
| Loretto Hospital lowest Chicago, IL · (773) 626-4300 HEP B VACCINE/HEP A VACCINE IN File of Nov 5, 2026 · source file | $53.74 | $89.56 | $53.74–$89.56 | 40% |
| Gottlieb Memorial Hospital Melrose Park, IL · (708) 681-3200 Twinrix Hep a & B+1 more line at this price File of Mar 31, 2026 · source file | $60.99 | $321.00 | $96.62–$269.00 | 81% |
| MacNeal Hospital Berwyn, IL · (708) 783-9100 Twinrix Hep a & B File of Mar 31, 2026 · source file | $60.99 | $321.00 | $60.99–$444.59 | 81% |
| Loyola University Medical Center Maywood, IL · (708) 216-9000 Twinrix Hep a & B+1 more line at this price File of Mar 31, 2026 · source file | $73.83 | $321.00 | $111.39–$338.33 | 77% |
| Humboldt Park Health Chicago, IL · (773) 292-8200 Hepatitis A and hepatitis B vaccine File of Sep 29, 2026 · source file | $82.91 | $296.10 | $97.71–$310.91 | 72% |
| NorthShore University HealthSystems Skokie Hospital Skokie, IL Hepa/Hepb Vaccine Adult Im File of Jan 1, 2025 · source file | $126.75 | $195.00 | $26.33–$106.47 | 35% |
| NorthShore University HealthSystems Glenbrook Hospital Glenview, IL Hepa/Hepb Vaccine Adult Im File of Jan 1, 2025 · source file | $126.75 | $195.00 | $26.33–$106.47 | 35% |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 NDC Description Not Available File of Apr 1, 2026 · source file | $126.78 | $126.78 | — | — |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Twinrix: 10 Syringe In 1 Carton (58160-815-52) / 1 Ml In 1 Syringe (58160-815-43) File of Apr 1, 2026 · source file | $126.97 | $126.97 | — | — |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Pr Hepatitis A & B Vaccine Hepa-Hepb Adult Im-Tvl+1 more line at this price File of Apr 1, 2026 · source file | $177.00 | $177.00 | — | — |
| Northshore University Healthsystem - Evanston Hospital Evanston, IL · (847) 570-2000 HEPA/HEPB VACCINE ADULT IM File of Apr 1, 2026 · source file | $195.00 | $195.00 | — | — |
| Endeavor Health Highland Park Hospital Highland Park, IL HEPA/HEPB VACCINE ADULT IM File of Apr 1, 2026 · source file | $195.00 | $195.00 | — | — |
| Swedish Covenant Health Chicago, IL · (773) 878-8200 HEPA/HEPB VACCINE ADULT IM File of Apr 1, 2026 · source file | $195.00 | $195.00 | — | — |
| Northwest Community Hospital Arlington Heights, IL · (847) 618-1000 Hb Hep A/Hep B Vacc Adult Im File of Apr 1, 2026 · source file | $200.85 | $200.85 | — | — |
| Uchicago Medicine AdventHealth Hinsdale Hinsdale, IL · (630) 856-9000 HEPATITIS A-HEP B RECOMB VAC 720-20 ELU-MCG/ML IM SUSY File of Apr 1, 2026 · source file | $211.64 | $846.57 | — | 75% |
| Uchicago Medicine AdventHealth Glenoaks Glendale Heights, IL · (630) 545-8000 HEPATITIS A-HEP B RECOMB VAC 720-20 ELU-MCG/ML IM SUSY File of Apr 1, 2026 · source file | $211.64 | $846.57 | — | 75% |
| Uchicago Medicine AdventHealth La Grange La Grange, IL · (708) 352-1200 HEPATITIS A-HEP B RECOMB VAC 720-20 ELU-MCG/ML IM SUSY File of Apr 1, 2026 · source file | $211.64 | $846.57 | — | 75% |
| Uchicago Medicine AdventHealth Bolingbrook Bolingbrook, IL · (630) 312-5000 HEPATITIS A-HEP B RECOMB VAC 720-20 ELU-MCG/ML IM SUSY File of Apr 1, 2026 · source file | $211.64 | $846.57 | — | 75% |
| Northwestern Medicine Kishwaukee Hospital DeKalb, IL · (815) 756-1521 HB Hepatitis a & B Vaccine Hepa-Hepb Adult Im File of Apr 1, 2026 · source file | $326.90 | $467.00 | $85.46–$467.00 | 30% |
| Palos Community Hospital Palos Heights, IL · (708) 923-4000 HB Hepatitis a & B Vaccine Hepa-Hepb Adult Im File of Apr 1, 2026 · source file | $326.90 | $467.00 | $74.72–$467.00 | 30% |
| Northwestern Medicine Central DuPage Hospital Winfield, IL · (630) 682-1600 HB Hepatitis a & B Vaccine Hepa-Hepb Adult Im File of Apr 1, 2026 · source file | $326.90 | $467.00 | $32.22–$467.00 | 30% |
| Northwestern Medicine McHenry Hospital McHenry, IL · (815) 344-5000 HB Hepatitis a & B Vaccine Hepa-Hepb Adult Im File of Apr 1, 2026 · source file | $326.90 | $467.00 | $90.13–$467.00 | 30% |
| Northwestern Medicine Valley West Hospital Sandwich, IL · (815) 786-8484 HB Hepatitis a & B Vaccine Hepa-Hepb Adult Im File of Apr 1, 2026 · source file | $326.90 | $467.00 | $88.73–$467.00 | 30% |
| Northwestern Memorial Hospital Chicago, IL · (312) 926-2000 HB Hepatitis a & B Vaccine Hepa-Hepb Adult Im File of Apr 1, 2026 · source file | $326.90 | $467.00 | $90.60–$467.00 | 30% |
| Northwestern Medicine Delnor Hospital Geneva, IL · (630) 208-3000 HB Hepatitis a & B Vaccine Hepa-Hepb Adult Im File of Apr 1, 2026 · source file | $326.90 | $467.00 | $69.58–$467.00 | 30% |
| Northwestern Lake Forest Hospital Lake Forest, IL · (847) 234-5600 HB Hepatitis a & B Vaccine Hepa-Hepb Adult Im File of Apr 1, 2026 · source file | $326.90 | $467.00 | $77.52–$467.00 | 30% |
| John H. Stroger, Jr. Hospital Chicago, IL · (312) 864-6000 HEPATITIS A-HEPATITIS B VACCINE 720 UNITS-20 MCG/ML PF INJ 1 ML File of Apr 1, 2026 · source file | $389.35 | $556.21 | $156.27–$444.97 | 30% |
| Northwest Community Hospital Arlington Heights, IL · (847) 618-1000 NDC Description Not Available File of Apr 1, 2026 · source file | $433.89 | $433.89 | — | — |
| Northwestern Memorial Hospital Chicago, IL · (312) 926-2000 HEPATITIS A AND B VACCINE (PF) 720 ELISA UNIT- 20 MCG/ML IM SYRG File of Apr 1, 2026 · source file | $509.77 | $728.25 | $141.28–$1,014.25 | 30% |
| Vista Medical Center East Waukegan, IL · (847) 360-3000 HEP-A HEP-B VAC ADUL File of Mar 31, 2025 · source file | $628.34 | $628.34 | $0.01–$314.17 | — |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Pr Hepatitis A & B Vaccine Hepa-Hepb Adult Im File of Apr 1, 2026 · source file | $678.00 | $678.00 | — | — |
| Northwestern Lake Forest Hospital Lake Forest, IL · (847) 234-5600 HEPATITIS A AND B VACCINE (PF) 720 ELISA UNIT- 20 MCG/ML IM SYRG File of Apr 1, 2026 · source file | $709.97 | $1,014.25 | $168.37–$1,014.25 | 30% |
Outpatient: lowest $53.74, median $211.64, highest $628.34 — a 11.7× difference within the same market.
As an inpatient, the same code is billed by 16 facilities here, median $195.00. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 14 of 17 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at 3 it is below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What hepatitis A and B vaccine (Twinrix) is, what the price covers and why prices differ: Hepatitis A and B vaccine (Twinrix) explained.