RSV antibody shot (100 mg dose) cost in Des Moines, IA
In Des Moines-West Des Moines, IA, 5 hospitals list a cash price for RSV antibody shot for infants and toddlers, larger dose (1 mL, 100 mg): from $421.85 to $1,733.20, with a median of $535.20. The lowest listed price is at MercyOne Newton Medical Center — $113.35 less than the median here. Across Iowa, the median is $583.60 at 42 hospitals.
Cash prices at 5 facilities across 4 cities for code 90381, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 27, 2026; the hospital files themselves were last updated between Jan 28, 2026 and Sep 23, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Des Moines-West Des Moines, IA.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list |
|---|---|---|---|---|
| MercyOne Newton Medical Center lowest Newton, IA · (641) 792-1273 HC Vaccine Respiratory Syncytial Virus Monoclonal Antibody Seasonal Dose 1 Ml Im File of Mar 31, 2026 · source file | $421.85 | $649.00 | $129.80–$649.00 | 35% |
| MercyOne Des Moines Medical Center Des Moines, IA · (515) 247-4436 HC Vaccine Respiratory Syncytial Virus Monoclonal Antibody Seasonal Dose 1 Ml Im File of Mar 31, 2026 · source file | $442.65 | $681.00 | $136.20–$904.37 | 35% |
| Madison County Memorial Hospital Winterset, IA · (515) 462-2373 Respiratory syncytial virus antibody, 1.0 mL dosage for injection into muscle File of Sep 23, 2026 · source file | $535.20 | $669.00 | $287.67–$669.00 | 20% |
| MercyOne West Des Moines Medical Center West Des Moines, IA HC Vaccine Respiratory Syncytial Virus Monoclonal Antibody Seasonal Dose 1 Ml Im File of Mar 31, 2026 · source file | $681.00 | $681.00 | $136.20–$904.37 | — |
| UnityPoint Health - Des Moines Iowa Methodist Medical Des Moines, IA · (515) 343-1000 NIRSEVIMAB-ALIP 100 MG/ML IM SOSY+1 more line at this price File of Jan 28, 2026 · source file | $1,733.20 | $2,166.50 | $441.97–$1,061.59 | 20% |
| MercyOne West Des Moines Medical Center West Des Moines, IA NIRSEVIMAB-ALIP 100 MG/ML INTRAMUSCULAR SYRINGE File of Mar 31, 2026 · source file | $2,736.70 | $2,736.70 | $511.37–$2,736.70 | — |
Outpatient: lowest $421.85, median $535.20, highest $1,733.20 — a 4.1× difference within the same market.
As an inpatient, the same code is billed by 4 facilities here, median $561.83. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 4 of 5 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
This is the larger dose (100 mg) of nirsevimab (Beyfortus), an antibody shot that protects infants from severe RSV. Babies weighing 5 kg (11 lb) or more in their first RSV season get this dose, and high-risk toddlers get two of them in their second season.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).