RSV antibody shot for babies cost in Chicago, IL
In Chicago-Naperville-Elgin, IL-IN, 25 hospitals list a cash price for RSV antibody shot for infants, seasonal dose (0.5 mL): from $145.53 to $5,401.94, with a median of $1,275.00. The lowest listed price is at Humboldt Park Health — $1,129.47 less than the median here. Across Illinois, the median is $1,238.00 at 30 hospitals.
Cash prices at 25 facilities across 19 cities for code 90380, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 23, 2026; the hospital files themselves were last updated between Mar 31, 2026 and Aug 24, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Chicago-Naperville-Elgin, IL-IN.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list | File date |
|---|---|---|---|---|---|
| Humboldt Park Health lowest Chicago, IL · (773) 292-8200 Respiratory syncytial virus antibody, 0.5 mL dosage for injection into muscle | $145.53 | $519.75 | $519.75 | 72% | Aug 24, 2026 source file |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Beyfortus: 1 Syringe In 1 Carton (49281-574-88) / 1 Ml In 1 Syringe | $253.50 | $253.50 | — | — | Apr 1, 2026 source file |
| Gottlieb Memorial Hospital Melrose Park, IL · (708) 681-3200 Rsv (Nirsevimab / Beyfortus) 50mg/0.5ml Im (Fc) | $270.94 | $1,426.00 | $429.23–$1,194.99 | 81% | Mar 31, 2026 source file |
| Gottlieb Memorial Hospital Melrose Park, IL · (708) 681-3200 Rsv (Nirsevimab / Beyfortus) 50mg/0.5ml Im (Fc) | $270.94 | $1,426.00 | $429.23–$1,194.99 | 81% | Mar 31, 2026 source file |
| Uchicago Medicine AdventHealth Hinsdale Hinsdale, IL · (630) 856-9000 NIRSEVIMAB-ALIP 50 MG/0.5 ML INTRAMUSCULAR SYRINGE | $304.20 | $507.00 | — | 40% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth Hinsdale Hinsdale, IL · (630) 856-9000 NIRSEVIMAB-ALIP 50 MG/0.5 ML INTRAMUSCULAR SYRINGE | $304.20 | $507.00 | — | 40% | Apr 1, 2026 source file |
| La Rabida Children's Hospital|LaRabida Childrens Hospital Chicago, IL · (773) 363-6700 BEYFORTUS; RSV; MONO; 0.5 ML D | $306.80 | $306.80 | — | — | Apr 1, 2026 source file |
| Loyola University Medical Center Maywood, IL · (708) 216-9000 Rsv (Nirsevimab / Beyfortus) 50mg/0.5ml Im (Fc) | $327.98 | $1,426.00 | $1,363.22 | 77% | Mar 31, 2026 source file |
| Loyola University Medical Center Maywood, IL · (708) 216-9000 Rsv (Nirsevimab / Beyfortus) 50mg/0.5ml Im (Fc) | $327.98 | $1,426.00 | $494.82–$1,503.00 | 77% | Mar 31, 2026 source file |
| Ingalls Memorial Hospital Harvey, IL · (708) 333-2300 Beyfortus: 1 Syringe In 1 Carton (49281-575-00) / .5 Ml In 1 Syringe | $507.00 | $507.00 | — | — | Apr 1, 2026 source file |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Beyfortus: 1 Syringe In 1 Carton (49281-575-00) / .5 Ml In 1 Syringe | $507.00 | $507.00 | — | — | Apr 1, 2026 source file |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Pr Rsv Monoclonal Antb Seasonal Dose 0.5Ml Im Use | $507.00 | $507.00 | — | — | Apr 1, 2026 source file |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Beyfortus: 5 Syringe In 1 Carton (49281-575-15) / .5 Ml In 1 Syringe | $507.00 | $507.00 | — | — | Apr 1, 2026 source file |
| Roseland Community Hospital Association Chicago, IL · (773) 995-3000 Respiratory syncytial virus antibody, 0.5 mL dosage for injection into muscle | $1,213.81 | $2,483.05 | $1,213.81–$2,731.36 | 51% | Jul 1, 2026 source file |
| Swedish Covenant Health Chicago, IL · (773) 878-8200 RSV MONOCOLONAL AB SEASONAL 0.5 ML DOSE IM USE | $1,238.00 | $1,238.00 | — | — | Apr 1, 2026 source file |
| Northshore University Healthsystem - Evanston Hospital Evanston, IL · (847) 570-2000 RSV MONOCOLONAL AB SEASONAL 0.5 ML DOSE IM USE | $1,238.00 | $1,238.00 | — | — | Apr 1, 2026 source file |
| Endeavor Health Clinical Operations Highland Park, IL RSV MONOCOLONAL AB SEASONAL 0.5 ML DOSE IM USE | $1,238.00 | $1,238.00 | — | — | Apr 1, 2026 source file |
| Elmhurst Memorial Hospital Elmhurst, IL · (331) 221-1000 HC RSV MONOCLONAL AB SEASONAL 0.5 ML DOSE IM USE | $1,275.00 | $1,275.00 | — | — | Apr 1, 2026 source file |
| Edward Hospital Naperville, IL · (630) 527-3000 HC RSV MONOCLONAL AB SEASONAL 0.5 ML DOSE IM USE | $1,275.00 | $1,275.00 | — | — | Apr 1, 2026 source file |
| Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, IL · (312) 227-4000 NIRSEVIMAB-ALIP 50 MG/0.5 ML INTRAMUSCULAR SYRINGE | $1,506.42 | $2,152.03 | $365.85–$8,500.00 | 30% | — source file |
| Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, IL · (312) 227-4000 H RSV MONOCLONAL ANTIBODY 0.5 ML FOR IM USE | $1,539.24 | $2,198.91 | $373.81–$8,500.00 | 30% | — source file |
| Palos Community Hospital Palos Heights, IL · (708) 923-4000 NIRSEVIMAB-ALIP 50 MG/0.5 ML IM SYRG | $1,776.07 | $2,537.25 | $354.96–$2,537.25 | 30% | Apr 1, 2026 source file |
| Northshore University Healthsystem - Evanston Hospital Evanston, IL · (847) 570-2000 Beyfortus: 5 Syringe In 1 Carton (49281-575-15) / .5 Ml In 1 Syringe | $1,835.66 | $1,835.66 | — | — | Apr 1, 2026 source file |
| Swedish Covenant Health Chicago, IL · (773) 878-8200 Beyfortus: 5 Syringe In 1 Carton (49281-575-15) / .5 Ml In 1 Syringe | $1,835.66 | $1,835.66 | — | — | Apr 1, 2026 source file |
| Endeavor Health Clinical Operations Highland Park, IL Beyfortus: 5 Syringe In 1 Carton (49281-575-15) / .5 Ml In 1 Syringe | $1,835.66 | $1,835.66 | — | — | Apr 1, 2026 source file |
| Northwest Community Hospital Arlington Heights, IL · (847) 618-1000 Beyfortus: 1 Syringe In 1 Carton (49281-575-00) / .5 Ml In 1 Syringe | $1,898.68 | $1,898.68 | — | — | Apr 1, 2026 source file |
| Northwestern Medicine McHenry Hospital McHenry, IL · (815) 344-5000 NIRSEVIMAB-ALIP 50 MG/0.5 ML IM SYRG | $2,034.37 | $2,906.25 | $560.91–$2,906.25 | 30% | Apr 1, 2026 source file |
| The Methodist Hospitals Merrillville, IN NIRSEVIMAB-ALIP 50 MG/0.5ML IM SOSY [184383] | $2,102.34 | $3,003.34 | $0.01–$2,672.97 | 30% | — source file |
| The Methodist Hospitals Gary, IN · (219) 886-4000 NIRSEVIMAB-ALIP 50 MG/0.5ML IM SOSY [184383] | $2,102.34 | $3,003.34 | $0.01–$2,672.97 | 30% | — source file |
| Swedish Covenant Health Chicago, IL · (773) 878-8200 Beyfortus: 1 Syringe In 1 Carton (49281-575-00) / .5 Ml In 1 Syringe | $2,351.43 | $2,351.43 | — | — | Apr 1, 2026 source file |
| Northshore University Healthsystem - Evanston Hospital Evanston, IL · (847) 570-2000 Beyfortus: 1 Syringe In 1 Carton (49281-575-00) / .5 Ml In 1 Syringe | $2,351.43 | $2,351.43 | — | — | Apr 1, 2026 source file |
| Endeavor Health Clinical Operations Highland Park, IL Beyfortus: 1 Syringe In 1 Carton (49281-575-00) / .5 Ml In 1 Syringe | $2,351.43 | $2,351.43 | — | — | Apr 1, 2026 source file |
| Northwestern Medicine Delnor Hospital Geneva, IL · (630) 208-3000 NIRSEVIMAB-ALIP 50 MG/0.5 ML IM SYRG | $2,387.70 | $3,411.00 | $555.99–$3,411.00 | 30% | Apr 1, 2026 source file |
| Northwestern Medicine Valley West Hospital Sandwich, IL · (815) 786-8484 NIRSEVIMAB-ALIP 50 MG/0.5 ML IM SYRG | $2,464.17 | $3,520.25 | $242.90–$3,520.25 | 30% | Apr 1, 2026 source file |
| Northwestern Lake Forest Hospital Lake Forest, IL · (847) 234-5600 NIRSEVIMAB-ALIP 50 MG/0.5 ML IM SYRG | $2,512.30 | $3,589.00 | $595.77–$3,589.00 | 30% | Apr 1, 2026 source file |
| Northwestern Medicine Kishwaukee Hospital DeKalb, IL · (815) 756-1521 NIRSEVIMAB-ALIP 50 MG/0.5 ML IM SYRG | $3,098.37 | $4,426.25 | $810.00–$4,426.25 | 30% | Apr 1, 2026 source file |
| Northwestern Medicine Central DuPage Hospital Winfield, IL · (630) 682-1600 NIRSEVIMAB-ALIP 50 MG/0.5 ML IM SYRG | $3,685.50 | $5,265.00 | $752.90–$5,265.00 | 30% | Apr 1, 2026 source file |
| Naperville Psychiatric Ventures Naperville, IL Synagis: .5 mL in 1 VIAL, SINGLE-DOSE (60574-4114-1) | $5,401.94 | $5,401.94 | — | — | Apr 1, 2026 source file |
| Elmhurst Memorial Hospital Elmhurst, IL · (331) 221-1000 Synagis: .5 mL in 1 VIAL, SINGLE-DOSE (60574-4114-1) | $5,401.94 | $5,401.94 | — | — | Apr 1, 2026 source file |
| Edward Hospital Naperville, IL · (630) 527-3000 Synagis: .5 mL in 1 VIAL, SINGLE-DOSE (60574-4114-1) | $5,401.94 | $5,401.94 | — | — | Apr 1, 2026 source file |
Outpatient: lowest $145.53, median $1,275.00, highest $5,401.94 — a 37.1× difference within the same market.
As an inpatient, the same code is billed by 14 facilities here, median $1,065.88. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 14 of 14 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at 3 it is below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
This is a ready-made RSV antibody shot for babies, given before or during their first RSV season to prevent severe illness. The 0.5 mL dose is for smaller infants; the larger dose has its own code (90381).
What the price covers
The price is for the antibody dose. Giving the shot is billed separately, usually with code 96380 or 96381 rather than the vaccine injection code 90471.
3 rows held back from this comparison
They are priced below $1 or below a tenth of the national median for code 90380 ($980.10). Such a line is almost always a physician's fee billed separately, an assistant's share or a placeholder — a real charge, but not the price of the procedure itself.
| Elmhurst Memorial Hospital Elmhurst, ILBeyfortus: 5 Syringe In 1 Carton (49281-575-15) / .5 Ml In 1 Syringe | $34.85 | file |
| Edward Hospital Naperville, ILBeyfortus: 5 Syringe In 1 Carton (49281-575-15) / .5 Ml In 1 Syringe | $34.85 | file |
| Naperville Psychiatric Ventures Naperville, ILBeyfortus: 5 Syringe In 1 Carton (49281-575-15) / .5 Ml In 1 Syringe | $34.85 | file |