HIV test (4th generation) cost in San Antonio, TX
In San Antonio-New Braunfels, TX, 10 hospitals list a cash price for HIV-1/2 antigen and antibody combination blood test (4th generation): from $34.25 to $1,122.36, with a median of $1,119.44. The lowest listed price is at University Health System — $1,085.19 less than the median here. Across Texas, the median is $140.83 at 262 hospitals.
- The median here, $1,119.44, is 1235% above the US median of $83.85.
- That is 46.5× Medicare's 2026 national rate for the same service ($24.08).
- San Antonio, TX ranks 4th of 4 metro areas in Texas by median, cheapest first.
- 6 of 10 hospitals list a cash price equal to their full list price, with no self-pay discount.
Cash prices at 10 facilities across 5 cities for code 87389, as an outpatient — the setting a self-pay patient normally buys. Collected Nov 4, 2026; the hospital files themselves were last updated between Jan 13, 2026 and Oct 7, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in San Antonio-New Braunfels, TX.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list |
|---|---|---|---|---|
| University Health System lowest San Antonio, TX · (210) 358-2000 HC HIV AG/AB COMBO SCRN File of Oct 7, 2026 · source file | $34.25 | $137.00 | $20.23–$342.50 | 75% |
| Santa Rosa Hospital - Westover Hills San Antonio, TX · (210) 703-8211 HC 87389 HIV1 AND HIV2 AG AND AB EVAL, S File of Jan 13, 2026 · source file | $47.52 | $144.00 | $4.41–$136.80 | 67% |
| Guadalupe Regional Medical Center Seguin, TX · (830) 379-2411 HIV-1 ANTIGEN,W HIV-1&HIV-2,1R File of May 21, 2026 · source file | $93.50 | $187.00 | $24.08–$187.00 | 50% |
| Methodist Hospital Atascosa Jourdanton, TX · (830) 769-3515 Infectious agent antigen detection by immunoassay technique (eg, enzyme immunoassay ºEIA», enzyme-linked immunosorbent assay ºELISA», fluorescence immunoassay ºFIA», immunochemiluminometric assay ºIMC +1 more line at this price File of Sep 1, 2026 · source file | $495.98 | $495.98 | $20.23–$421.58 | — |
| Medina Regional Hospital Hondo, TX · (830) 426-7700 HIV I/II (Ag/Ab) File of Jul 29, 2026 · source file | $1,116.51 | $1,240.56 | $38.53–$1,240.56 | 10% |
| Methodist Hospital Westover Hills San Antonio, TX · (210) 638-2101 Infectious agent antigen detection by immunoassay technique (eg, enzyme immunoassay ºEIA», enzyme-linked immunosorbent assay ºELISA», fluorescence immunoassay ºFIA», immunochemiluminometric assay ºIMC +1 more line at this price File of Sep 1, 2026 · source file | $1,122.36 | $1,122.36 | $20.23–$954.01 | — |
| Methodist Hospital Landmark San Antonio, TX · (210) 638-2101 Infectious agent antigen detection by immunoassay technique (eg, enzyme immunoassay ºEIA», enzyme-linked immunosorbent assay ºELISA», fluorescence immunoassay ºFIA», immunochemiluminometric assay ºIMC +1 more line at this price File of Sep 1, 2026 · source file | $1,122.36 | $1,122.36 | $20.23–$954.01 | — |
| Methodist Hospital San Antonio, TX · (210) 575-4000 HIV-1AG HIV-1/2AB SINGLE+1 more line at this price File of Sep 1, 2026 · source file | $1,122.36 | $1,122.36 | $20.23–$1,122.36 | — |
| Methodist Hospital Stone Oak Spring Branch, TX · (210) 638-2101 HIV-1AG HIV-1/2AB SINGLE+1 more line at this price File of Sep 1, 2026 · source file | $1,122.36 | $1,122.36 | $20.23–$954.01 | — |
| Metropolitan Methodist San Antonio, TX · (210) 575-4000 Infectious agent antigen detection by immunoassay technique (eg, enzyme immunoassay ºEIA», enzyme-linked immunosorbent assay ºELISA», fluorescence immunoassay ºFIA», immunochemiluminometric assay ºIMC +1 more line at this price File of Sep 1, 2026 · source file | $1,122.36 | $1,122.36 | $20.23–$954.01 | — |
Outpatient: lowest $34.25, median $1,119.44, highest $1,122.36 — a 32.8× difference within the same market.
As an inpatient, the same code is billed by 4 facilities here, median $87.75. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 4 of 10 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What HIV test (4th generation) is, what the price covers and why prices differ: HIV test (4th generation) explained.