AFP test cost in Boston, MA
In Boston-Cambridge-Newton, MA-NH, 26 hospitals list a cash price for alpha-fetoprotein (AFP) blood test: from $28.14 to $802.00, with a median of $107.50. The lowest listed price is at Boston Medical Center South — $79.36 less than the median here. Across Massachusetts, the median is $81.17 at 33 hospitals.
Cash prices at 26 facilities across 19 cities for code 82105, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 29, 2026; the hospital files themselves were last updated between Jan 28, 2026 and Sep 1, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Boston-Cambridge-Newton, MA-NH.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list |
|---|---|---|---|---|
| Boston Medical Center South lowest Brockton, MA · (508) 427-3000 HC Chg Alpha-Fetoprotein Serum source file | $28.14 | $62.53 | $14.79–$394.86 | 55% |
| Boston Medical Center Boston, MA · (617) 638-8000 HC Chg Alpha-Fetoprotein Serum source file | $32.85 | $73.00 | $14.51–$512.54 | 55% |
| Boston Medical Center Brighton Boston, MA · (617) 789-3000 HC Chg Alpha-Fetoprotein Serum source file | $33.92 | $75.37 | $14.79–$475.07 | 55% |
| Melrosewakefield Healthcare Melrose, MA · (781) 979-3000 HC Alpha-Fetoprotein Serum source file | $41.30 | $59.00 | $20.65–$530.75 | 30% |
| Lowell General Hospital Lowell, MA · (978) 937-6000 HC Alpha-Fetoprotein Serum source file | $41.30 | $59.00 | $20.65–$68.89 | 30% |
| Tufts Medical Center Boston, MA · (617) 636-5000 HC Alpha-Fetoprotein Serum source file | $41.30 | $59.00 | $15.49–$72.76 | 30% |
| Signature Healthcare Brockton Hospital Brockton, MA · (508) 941-7000 ALPHA FETOPROTEIN SERUM File of Jan 28, 2026 · source file | $48.30 | $69.00 | $16.43–$53.79 | 30% |
| Cambridge Health Alliance Cambridge, MA · (617) 665-1000 HC Alpha-1-Fetoprotein, Serum+1 more line at this price source file | $51.00 | $51.00 | $14.79–$115.72 | — |
| Emerson Hospital Concord, MA · (978) 369-1400 ALPHA-FETOPROTEIN SERUM File of May 18, 2026 · source file | $52.50 | $70.00 | $15.92–$71.27 | 25% |
| Southcoast Hospitals Group - Tobey Hospital Campus Wareham, MA · (508) 679-3131 HC Alpha-Fetoprotein- Serum source file | $67.00 | $134.00 | $16.77–$101.97 | 50% |
| Beth Israel Deaconess Hospital - Plymouth Plymouth, MA · (508) 746-2000 CHG ALPHA-FETOPROTEIN SERUM File of Apr 1, 2026 · source file | $76.00 | $76.00 | — | — |
| Beth Israel Deaconess Hospital - Needham Needham, MA · (781) 453-3002 CHG ALPHA-FETOPROTEIN SERUM File of Apr 1, 2026 · source file | $93.00 | $93.00 | — | — |
| Winchester Hospital Winchester, MA · (781) 729-9000 CHG ALPHA-FETOPROTEIN SERUM File of Apr 1, 2026 · source file | $102.00 | $102.00 | — | — |
| Lahey Hospital & Medical Center, Burlington Burlington, MA · (781) 744-5100 CHG ALPHA-FETOPROTEIN SERUM File of Apr 1, 2026 · source file | $113.00 | $113.00 | — | — |
| Beth Israel Deaconess Hospital-Milton Milton, MA · (617) 696-4600 CHG ALPHA-FETOPROTEIN SERUM File of Apr 1, 2026 · source file | $113.00 | $113.00 | — | — |
| New England Baptist Hospital Boston, MA · (617) 754-5800 CHG ALPHA-FETOPROTEIN SERUM File of Apr 1, 2026 · source file | $139.00 | $139.00 | — | — |
| Beth Israel Deaconess Medical Center Boston, MA · (617) 667-7000 CHG ALPHA-FETOPROTEIN SERUM File of Apr 1, 2026 · source file | $159.00 | $159.00 | — | — |
| Shriners Childrens - Boston Boston, MA · (617) 722-3000 ALPHA-FETOPROTEIN SERUM source file | $162.70 | $162.70 | $14.51–$817.41 | — |
| Mount Auburn Hospital Cambridge, MA · (617) 492-3500 CHG ALPHA-FETOPROTEIN SERUM File of Apr 1, 2026 · source file | $168.00 | $168.00 | — | — |
| Anna Jaques Hospital Newburyport, MA · (978) 463-1000 CHG ALPHA-FETOPROTEIN SERUM File of Apr 1, 2026 · source file | $184.00 | $184.00 | — | — |
| Dover Emergency Room Dover, NH · (603) 436-5110 ALPHA FETOPROT SERUM MAT File of Sep 1, 2026 · source file | $210.00 | $210.00 | $53.97–$199.50 | — |
| Portsmouth Regional Hospital Portsmouth, NH · (603) 436-5110 ALPHA FETOPROT SERUM MAT File of Sep 1, 2026 · source file | $210.00 | $210.00 | $53.97–$199.50 | — |
| Seabrook Emergency Seabrook, NH · (603) 436-5110 ALPHA FETOPROT SERUM MAT File of Sep 1, 2026 · source file | $210.00 | $210.00 | $53.97–$199.50 | — |
| Exeter Hospital Exeter, NH · (603) 778-7311 CHG ALPHA-FETOPROTEIN SERUM File of Apr 1, 2026 · source file | $215.00 | $215.00 | — | — |
| Seabrook Emergency Seabrook, NH · (603) 436-5110 ALPHA FETOPROT SERUM File of Sep 1, 2026 · source file | $760.00 | $760.00 | $195.32–$722.00 | — |
| Portsmouth Regional Hospital Portsmouth, NH · (603) 436-5110 ALPHA FETOPROT SERUM File of Sep 1, 2026 · source file | $760.00 | $760.00 | $195.32–$722.00 | — |
| Dover Emergency Room Dover, NH · (603) 436-5110 ALPHA FETOPROT SERUM File of Sep 1, 2026 · source file | $760.00 | $760.00 | $195.32–$722.00 | — |
| Parkland Medical Center Derry, NH · (603) 421-2100 ALPHA FETOPROT SERUM File of Sep 1, 2026 · source file | $802.00 | $802.00 | $168.42–$761.90 | — |
| Plaistow Fser Plaistow, NH · (603) 421-2100 ALPHA FETOPROT SERUM File of Sep 1, 2026 · source file | $802.00 | $802.00 | $168.42–$761.90 | — |
| Plaistow Fser Plaistow, NH · (603) 421-2100 ALPHA FETOPROT SERUM MAT File of Sep 1, 2026 · source file | $990.75 | $990.75 | $208.06–$941.21 | — |
| Parkland Medical Center Derry, NH · (603) 421-2100 ALPHA FETOPROT SERUM MAT File of Sep 1, 2026 · source file | $990.75 | $990.75 | $208.06–$941.21 | — |
Outpatient: lowest $28.14, median $107.50, highest $802.00 — a 28.5× difference within the same market.
As an inpatient, the same code is billed by 20 facilities here, median $84.50. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 11 of 16 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
An AFP test measures a protein made by the liver and by a developing baby. In adults it is used to watch for liver cancer in people with cirrhosis and to follow some testicular cancers.
What the price covers
The price usually covers running the test. The blood draw (36415) is often billed as a separate line.