NIPT prenatal DNA test cost in Houston, TX
In Houston-Pasadena-The Woodlands, TX, 12 hospitals list a cash price for prenatal cell-free DNA screen for trisomy 21, 18 and 13 (NIPT): from $375.00 to $7,218.00, with a median of $375.00. The lowest listed price is at The Methodist Hospital and 8 other hospitals. Across Texas, the median is $870.00 at 99 hospitals.
- The median here, $375.00, is 64% below the US median of $1,041.15.
- That is 0.5× Medicare's 2026 national rate for the same service ($759.05).
- Houston, TX has the lowest median of 2 metro areas in Texas with at least 10 hospitals pricing this code.
- 1 of 12 hospitals list a cash price equal to their full list price, with no self-pay discount.
Cash prices at 12 facilities across 8 cities for code 81420, as an outpatient — the setting a self-pay patient normally buys. Collected Nov 3, 2026; the hospital files themselves were last updated between Mar 24, 2026 and Sep 1, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Houston-Pasadena-The Woodlands, TX.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list |
|---|---|---|---|---|
| The Methodist Hospital lowest Houston, TX · (713) 790-2221 HC NON-INVAS PRENATAL TEST FETAL ANEUPLOIDY File of Apr 1, 2026 · source file | $375.00 | $750.00 | — | 50% |
| Houston Methodist Clear Lake Hospital lowest Nassau Bay, TX · (281) 333-5503 HC NON-INVAS PRENATAL TEST FETAL ANEUPLOIDY File of Apr 1, 2026 · source file | $375.00 | $750.00 | — | 50% |
| Houston Methodist Baytown Hospital lowest Baytown, TX · (281) 420-8600 HC NON-INVAS PRENATAL TEST FETAL ANEUPLOIDY File of Apr 1, 2026 · source file | $375.00 | $750.00 | — | 50% |
| Houston Methodist Cypress Hospital lowest Cypress, TX · (346) 618-1506 HC NON-INVAS PRENATAL TEST FETAL ANEUPLOIDY File of Apr 1, 2026 · source file | $375.00 | $750.00 | — | 50% |
| Methodist West Houston Hospital lowest Houston, TX · (832) 522-1000 HC NON-INVAS PRENATAL TEST FETAL ANEUPLOIDY File of Apr 1, 2026 · source file | $375.00 | $750.00 | — | 50% |
| Houston Methodist Continuing Care Hospital lowest Katy, TX HC NON-INVAS PRENATAL TEST FETAL ANEUPLOIDY File of Apr 1, 2026 · source file | $375.00 | $750.00 | — | 50% |
| Methodist Sugar Land Hospital lowest Sugar Land, TX · (281) 274-8000 HC NON-INVAS PRENATAL TEST FETAL ANEUPLOIDY File of Apr 1, 2026 · source file | $375.00 | $750.00 | — | 50% |
| Methodist Willowbrook Hospital lowest Houston, TX · (281) 477-1000 HC NON-INVAS PRENATAL TEST FETAL ANEUPLOIDY File of Apr 1, 2026 · source file | $375.00 | $750.00 | — | 50% |
| Houston Methodist The Woodlands Hospital lowest The Woodlands, TX · (936) 270-2000 HC NON-INVAS PRENATAL TEST FETAL ANEUPLOIDY File of Apr 1, 2026 · source file | $375.00 | $750.00 | — | 50% |
| Harris Health Houston, TX · (713) 873-2000 FETAL CHROMO ANEUPLOIDY MATERNIT21 PLUS CORE + SCA (LABCORP)-LAB5051 File of Mar 24, 2026 · source file | $759.05 | $1,491.00 | $637.60–$1,765.13 | 49% |
| Harris Health Taub Loop Houston, TX · (713) 873-2000 FETAL CHROMO ANEUPLOIDY MATERNIT21 PLUS CORE + SCA (LABCORP)-LAB5051 File of Mar 24, 2026 · source file | $759.05 | $1,491.00 | $637.60–$1,765.13 | 49% |
| The Womans Hospital of Texas Houston, TX · (713) 790-1234 Fetal chromosomal aneuploidy (eg, trisomy 21, monosomy X) genomic sequence analysis panel, circulating cell-free fetal DNA in maternal blood, must include analysis of chromosomes 13, 18, and 21 +1 more line at this price File of Sep 1, 2026 · source file | $7,218.00 | $7,218.00 | $433.08–$6,135.30 | — |
Outpatient: lowest $375.00, median $375.00, highest $7,218.00 — a 19.2× difference within the same market.
As an inpatient, the same code is billed by 11 facilities here, median $375.00. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 2 of 3 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What NIPT prenatal DNA test is, what the price covers and why prices differ: NIPT prenatal DNA test explained.