Lab tests CPT 81420 Outpatient

NIPT prenatal DNA test cost in Detroit, MI

In Detroit-Warren-Dearborn, MI, 15 hospitals list a cash price for Prenatal cell-free DNA screen for trisomy 21, 18 and 13 (NIPT): from $138.60 to $1,047.49, with a median of $300.00. The lowest listed price is at Henry Ford Health and 2 other hospitals — $161.40 less than the median here. Across Michigan, the median is $300.00 at 16 hospitals.

Cash prices at 15 facilities across 9 cities for code 81420, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 23, 2026; the hospital files themselves were last updated between Dec 31, 2025 and Sep 2, 2026.

Lowest$138.60Henry Ford Health + 2 more
Median$300.00half pay less
Highest$1,047.49in this market
Difference7.6×highest vs lowest

Where each hospital's price falls

Each dot is one hospital's cash price on a scale from the lowest to the highest in Detroit-Warren-Dearborn, MI.

median
Lowest $138.60Highest $1,047.49

Hospitals, cheapest first

HospitalCash price List priceInsurers payOff listFile date
Henry Ford Health lowest Warren, MI FETAL CHRMOML ANEUPLOIDY W/22Q $138.60 $247.50 $247.50 44% —
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Henry Ford Health lowest Detroit, MI FETAL CHRMOML ANEUPLOIDY W/22Q $138.60 $247.50 $247.50 44% —
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Henry Ford Health lowest East China Township, MI FETAL CHRMOML ANEUPLOIDY W/22Q $138.60 $247.50 $247.50 44% —
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Henry Ford Health East China Township, MI NIPT FETAL CHRMOML ANEUPLOIDY $154.00 $275.00 $275.00 44% —
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Henry Ford Health Warren, MI NIPT FETAL CHRMOML ANEUPLOIDY $154.00 $275.00 $275.00 44% —
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Henry Ford Health Detroit, MI NIPT FETAL CHRMOML ANEUPLOIDY $154.00 $275.00 $275.00 44% —
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Karmanos Cancer Center John R Detroit, MI FETAL CHROM ANALYSIS(SOA) $205.00 $410.00 $151.29–$1,563.38 50% Dec 31, 2025
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Henry Ford Health Detroit, MI FETAL ANEUPLOIDY (PANORAMA) $252.00 $450.00 $450.00 44% —
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Henry Ford Health East China Township, MI FETAL ANEUPLOIDY (PANORAMA) $252.00 $450.00 $450.00 44% —
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Henry Ford Health Warren, MI FETAL ANEUPLOIDY (PANORAMA) $252.00 $450.00 $450.00 44% —
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VHS Huron Valley-Sinai Hospital Inc Commerce Charter Twp, MI FETAL INFORMA SEQ XY SEQUENCE $300.00 $400.00 $1.00–$802.33 25% May 20, 2026
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VHS Sinai Grace Hospital Inc Detroit, MI FETAL INFORMA SEQ XY SEQUENCE $300.00 $400.00 — 25% Apr 8, 2026
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Vhs Harper-Hutzel Hospital INC Detroit, MI FETAL INFORMA SEQ XY SEQUENCE $300.00 $400.00 $1.00–$802.33 25% Sep 2, 2026
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Vhs Harper-Hutzel Hospital INC Detroit, MI FETAL INFORMA SEQ XY SEQUENCE $300.00 $400.00 $1.00–$802.33 25% Aug 20, 2026
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VHS Detroit Receiving Hospital Inc Detroit, MI FETAL INFORMA SEQ XY SEQUENCE $300.00 $400.00 — 25% Apr 7, 2026
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VHS Childrens Hospital of Michigan Inc Detroit, MI FETAL INFORMA SEQ XY SEQUENCE $300.00 $400.00 — 25% Apr 6, 2026
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VHS Rehabilitation Institute of Michigan Inc Detroit, MI FETAL INFORMA SEQ XY SEQUENCE $300.00 $400.00 — 25% Apr 8, 2026
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Henry Ford Health Rochester, MI FETAL CHRMOML ANEUPLOIDY $356.75 $759.05 $759.05 53% —
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Henry Ford Health East China Township, MI MATERNIT21 PLUS CORE-LC $582.96 $1,041.00 $625.00–$1,041.00 44% —
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Henry Ford Health East China Township, MI MATERNIT21 PLUS CORE-LC $582.96 $1,041.00 $625.00–$1,041.00 44% —
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Henry Ford Health Detroit, MI MATERNIT21 PLUS CORE-LC $635.60 $1,135.00 $501.02–$1,135.00 44% —
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Henry Ford Health Detroit, MI MATERNIT21 PLUS CORE-LC $635.60 $1,135.00 $501.02–$1,135.00 44% —
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Henry Ford Health Warren, MI MATERNIT21 PLUS CORE-LC $635.60 $1,135.00 $625.00–$1,135.00 44% —
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Henry Ford Health Warren, MI MATERNIT21 PLUS CORE-LC $635.60 $1,135.00 $625.00–$1,135.00 44% —
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Henry Ford Health East China Township, MI MATERNIT FET CHR ANEUP-LC $869.12 $1,552.00 $625.00–$1,552.00 44% —
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Henry Ford Health East China Township, MI MATERNIT FET CHR ANEUP-LC $869.12 $1,552.00 $625.00–$1,552.00 44% —
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Henry Ford Health Detroit, MI MATERNIT FET CHR ANEUP-LC $948.08 $1,693.00 $501.02–$1,693.00 44% —
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Henry Ford Health Detroit, MI MATERNIT FET CHR ANEUP-LC $948.08 $1,693.00 $501.02–$1,693.00 44% —
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Henry Ford Health Warren, MI MATERNIT FET CHR ANEUP-LC $948.08 $1,693.00 $625.00–$1,693.00 44% —
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Henry Ford Health Warren, MI MATERNIT FET CHR ANEUP-LC $948.08 $1,693.00 $625.00–$1,693.00 44% —
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Henry Ford Health System Detroit, MI FETAL CHRMOML ANEUPLOIDY $1,047.49 — $619.34–$1,047.49 — Jun 28, 2026
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Henry Ford Macomb Hospital Corporation Clinton Twp, MI FETAL CHRMOML ANEUPLOIDY $1,047.49 — $619.34–$1,047.49 — Jun 28, 2026
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Henry Ford Health System West Bloomfield, MI FETAL CHRMOML ANEUPLOIDY $1,047.49 — $619.34–$1,047.49 — Jun 28, 2026
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Henry Ford Wyandotte Hospital Wyandotte, MI FETAL CHRMOML ANEUPLOIDY $1,047.49 — $619.34–$1,047.49 — Jun 28, 2026
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Outpatient: lowest $138.60, median $300.00, highest $1,047.49 — a 7.6× difference within the same market.

As an inpatient, the same code is billed by 7 facilities here, median $300.00. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.

Cash or insurance?

At 7 of 11 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at 4 it is below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.

What it is

NIPT analyzes fragments of fetal DNA that circulate in the mother's blood to screen for Down syndrome (trisomy 21) and trisomies 18 and 13. It can be done from about 10 weeks of pregnancy. It is a screening test, so a positive result needs a diagnostic test to confirm.

What the price covers

The price usually covers the DNA analysis of one blood sample. The blood draw, genetic counseling and any added screens, such as sex chromosomes or microdeletions, may be billed separately.