NIPT prenatal DNA test cost in Cleveland, OH
In Cleveland, OH, 12 hospitals list a cash price for prenatal cell-free DNA screen for trisomy 21, 18 and 13 (NIPT): from $523.80 to $3,404.05, with a median of $3,404.05. The lowest listed price is at Mercy Health Regional Medical Center — $2,880.25 less than the median here. Across Ohio, the median is $1,456.00 at 81 hospitals.
- The median here, $3,404.05, is 226% above the US median of $1,043.03.
- That is 4.5× Medicare's 2026 national rate for the same service ($759.05).
- Cleveland, OH ranks 3rd of 3 metro areas in Ohio by median, cheapest first.
- Every hospital here lists a cash price below its full list price.
Cash prices at 12 facilities across 10 cities for code 81420, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 23, 2026; the hospital files themselves were last updated between Apr 1, 2026 and Jun 16, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Cleveland, OH.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list |
|---|---|---|---|---|
| Mercy Health Regional Medical Center lowest Lorain, OH · (440) 960-4000 HC So Fetal Chrmoml Aneuploidy+1 more line at this price File of Apr 1, 2026 · source file | $523.80 | $873.00 | — | 40% |
| Mercy Health Regional Medical Center Lorain, OH · (440) 960-4000 HC Fetal Chromosomal Aneuploidy Genomic Seq Analys File of Apr 1, 2026 · source file | $606.60 | $1,011.00 | — | 40% |
| Mercy Health Allen Hospital Oberlin, OH · (440) 334-7039 HC So Fetal Chrmoml Aneuploidy+1 more line at this price File of Apr 1, 2026 · source file | $841.80 | $1,403.00 | — | 40% |
| Mercy Health Allen Hospital Oberlin, OH · (440) 334-7039 HC Fetal Chromosomal Aneuploidy Genomic Seq Analys File of Apr 1, 2026 · source file | $929.40 | $1,549.00 | — | 40% |
| The Cleveland Clinic Foundation Cleveland, OH · (216) 952-9829 MATGEN FETAL CHRMOML ANEU+1 more line at this price File of Jun 16, 2026 · source file | $3,404.05 | $5,237.00 | $645.00–$1,707.87 | 35% |
| Medina Hospital Medina, OH · (330) 725-1000 MATERNIT21 PLUS File of Jun 15, 2026 · source file | $3,404.05 | $5,237.00 | $138.30–$1,743.54 | 35% |
| South Pointe Hospital Warrensville Heights, OH · (216) 491-6523 MATERNIT21 PLUS File of Jun 15, 2026 · source file | $3,404.05 | $5,237.00 | $1,481.02–$5,237.00 | 35% |
| Lutheran Hospital Cleveland, OH · (216) 696-4300 MATERNIT21 PLUS File of Jun 15, 2026 · source file | $3,404.05 | $5,237.00 | $1,481.02–$5,237.00 | 35% |
| Fairview Hospital Cleveland, OH · (216) 476-7000 MATERNIT21 PLUS File of Jun 15, 2026 · source file | $3,404.05 | $5,237.00 | $1,481.02–$5,237.00 | 35% |
| Euclid Hospital Euclid, OH · (216) 531-9000 MATERNIT21 PLUS File of Jun 15, 2026 · source file | $3,404.05 | $5,237.00 | $1,481.02–$5,237.00 | 35% |
| Lodi Community Hospital Lodi, OH · (330) 948-1222 MATERNIT21 PLUS File of Jun 15, 2026 · source file | $3,404.05 | $5,237.00 | $1,481.02–$5,237.00 | 35% |
| Marymount Hospital Garfield Heights, OH · (216) 587-8210 MATERNIT21 PLUS File of Jun 15, 2026 · source file | $3,404.05 | $5,237.00 | $0.95–$1,709.76 | 35% |
| Hillcrest Hospital Mayfield Heights, OH · (440) 312-4500 MATERNIT21 PLUS File of Jun 15, 2026 · source file | $3,404.05 | $5,237.00 | $147.78–$2,202.00 | 35% |
| Cleveland Clinic Avon Hospital Avon, OH · (440) 695-5000 MATERNIT21 PLUS File of Jun 15, 2026 · source file | $3,404.05 | $5,237.00 | $0.95–$1,709.76 | 35% |
Outpatient: lowest $523.80, median $3,404.05, highest $3,404.05 — a 6.5× difference within the same market.
As an inpatient, the same code is billed by 12 facilities here, median $3,404.05. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 5 of 10 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What NIPT prenatal DNA test is, what the price covers and why prices differ: NIPT prenatal DNA test explained.