NIPT prenatal DNA test cost in Cleveland, OH
In Cleveland, OH, 13 hospitals list a cash price for prenatal cell-free DNA screen for trisomy 21, 18 and 13 (NIPT): from $523.80 to $3,404.05, with a median of $3,404.05. The lowest listed price is at Mercy Health Regional Medical Center — $2,880.25 less than the median here. Across Ohio, the median is $1,592.40 at 66 hospitals.
Cash prices at 13 facilities across 11 cities for code 81420, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 23, 2026; the hospital files themselves were last updated between Apr 1, 2026 and Jun 16, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Cleveland, OH.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list | File date |
|---|---|---|---|---|---|
| Mercy Health Regional Medical Center lowest Lorain, OH · (440) 960-4000 HC So Fetal Chrmoml Aneuploidy | $523.80 | $873.00 | — | 40% | — source file |
| Mercy Health Regional Medical Center lowest Lorain, OH · (440) 960-4000 HC So1 Fetal Chrmoml Aneuploidy | $523.80 | $873.00 | — | 40% | — source file |
| Mercy Health Regional Medical Center Lorain, OH · (440) 960-4000 HC Fetal Chromosomal Aneuploidy Genomic Seq Analys | $606.60 | $1,011.00 | — | 40% | — source file |
| Mercy Health Allen Hospital Oberlin, OH · (440) 334-7039 HC So1 Fetal Chrmoml Aneuploidy | $841.80 | $1,403.00 | — | 40% | — source file |
| Mercy Health Allen Hospital Oberlin, OH · (440) 334-7039 HC So Fetal Chrmoml Aneuploidy | $841.80 | $1,403.00 | — | 40% | — source file |
| Mercy Health Allen Hospital Oberlin, OH · (440) 334-7039 HC Fetal Chromosomal Aneuploidy Genomic Seq Analys | $929.40 | $1,549.00 | — | 40% | — source file |
| Summa Health System Akron, OH · (330) 375-3000 Hc Fetal Chrmoml Aneuploidy | $2,811.75 | $2,811.75 | — | — | Apr 1, 2026 source file |
| Hillcrest Hospital Mayfield Heights, OH · (440) 312-4500 MATERNIT21 PLUS | $3,404.05 | $5,237.00 | $147.78–$2,202.00 | 35% | Jun 15, 2026 source file |
| Medina Hospital Medina, OH · (330) 725-1000 MATERNIT21 PLUS | $3,404.05 | $5,237.00 | $138.30–$1,743.54 | 35% | Jun 15, 2026 source file |
| Lutheran Hospital Cleveland, OH · (216) 696-4300 MATERNIT21 PLUS | $3,404.05 | $5,237.00 | $1,481.02–$5,237.00 | 35% | Jun 15, 2026 source file |
| Marymount Hospital Garfield Heights, OH · (216) 587-8210 MATERNIT21 PLUS | $3,404.05 | $5,237.00 | $0.95–$1,709.76 | 35% | Jun 15, 2026 source file |
| South Pointe Hospital Warrensville Heights, OH · (216) 491-6523 MATERNIT21 PLUS | $3,404.05 | $5,237.00 | $1,481.02–$5,237.00 | 35% | Jun 15, 2026 source file |
| Lodi Community Hospital Lodi, OH · (330) 948-1222 MATERNIT21 PLUS | $3,404.05 | $5,237.00 | $1,481.02–$5,237.00 | 35% | Jun 15, 2026 source file |
| Cleveland Clinic Avon Hospital Avon, OH · (440) 695-5000 MATERNIT21 PLUS | $3,404.05 | $5,237.00 | $0.95–$1,709.76 | 35% | Jun 15, 2026 source file |
| Cleveland Clinic Health System - East Region Euclid, OH MATERNIT21 PLUS | $3,404.05 | $5,237.00 | $1,481.02–$5,237.00 | 35% | Jun 15, 2026 source file |
| The Cleveland Clinic Foundation Cleveland, OH · (216) 952-9829 MATERNIT21 PLUS | $3,404.05 | $5,237.00 | $645.00–$1,707.87 | 35% | Jun 16, 2026 source file |
| The Cleveland Clinic Foundation Cleveland, OH · (216) 952-9829 MATGEN FETAL CHRMOML ANEU | $3,404.05 | $5,237.00 | $645.00–$1,707.87 | 35% | Jun 16, 2026 source file |
| The Cleveland Clinic Foundation Cleveland, OH · (216) 952-9829 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ ANALYS | $3,404.05 | $5,237.00 | $1.10–$2,323.30 | 35% | Jun 16, 2026 source file |
| Fairview Hospital Cleveland, OH · (216) 476-7000 MATERNIT21 PLUS | $3,404.05 | $5,237.00 | $1,481.02–$5,237.00 | 35% | Jun 15, 2026 source file |
Outpatient: lowest $523.80, median $3,404.05, highest $3,404.05 — a 6.5× difference within the same market.
As an inpatient, the same code is billed by 13 facilities here, median $3,404.05. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 5 of 10 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
NIPT analyzes fragments of fetal DNA that circulate in the mother's blood to screen for Down syndrome (trisomy 21) and trisomies 18 and 13. It can be done from about 10 weeks of pregnancy. It is a screening test, so a positive result needs a diagnostic test to confirm.
What the price covers
The price usually covers the DNA analysis of one blood sample. The blood draw, genetic counseling and any added screens, such as sex chromosomes or microdeletions, may be billed separately.