NIPT prenatal DNA test cost in Chicago, IL — inpatient
In Chicago-Naperville-Elgin, IL-IN, 20 hospitals list a cash price for prenatal cell-free DNA screen for trisomy 21, 18 and 13 (NIPT) as an inpatient: from $400.00 to $1,380.00, with a median of $462.50. The lowest listed price is at Uchicago Medicine AdventHealth Glenoaks and 3 other hospitals — $62.50 less than the median here. Across Illinois, the median is $669.44 at 35 hospitals.
Cash prices at 20 facilities across 15 cities for code 81420, as an inpatient (admitted to hospital) . Collected Sep 23, 2026; the hospital files themselves were last updated between Mar 17, 2025 and Apr 1, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Chicago-Naperville-Elgin, IL-IN.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list | File date |
|---|---|---|---|---|---|
| Uchicago Medicine AdventHealth Glenoaks lowest Glendale Heights, IL · (630) 545-8000 HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY | $400.00 | $1,600.00 | — | 75% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth Glenoaks lowest Glendale Heights, IL · (630) 545-8000 HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY | $400.00 | $1,600.00 | — | 75% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth La Grange lowest La Grange, IL · (708) 352-1200 HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY | $400.00 | $1,600.00 | — | 75% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth La Grange lowest La Grange, IL · (708) 352-1200 HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY | $400.00 | $1,600.00 | — | 75% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth Hinsdale lowest Hinsdale, IL · (630) 856-9000 HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY | $400.00 | $1,600.00 | — | 75% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth Bolingbrook lowest Bolingbrook, IL · (630) 312-5000 HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY | $400.00 | $1,600.00 | — | 75% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth Bolingbrook lowest Bolingbrook, IL · (630) 312-5000 HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY | $400.00 | $1,600.00 | — | 75% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth Hinsdale lowest Hinsdale, IL · (630) 856-9000 HC MOLECULAR PATHOLOGY - FETAL CHROMOSOME ANEUPLOIDY | $400.00 | $1,600.00 | — | 75% | Apr 1, 2026 source file |
| Advocate Trinity Hospital Chicago, IL · (773) 967-5002 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ | $462.50 | $925.00 | $404.23–$740.00 | 50% | Nov 4, 2025 source file |
| Advocate South Suburban Hospital Hazel Crest, IL FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ | $462.50 | $925.00 | $404.23–$740.00 | 50% | Nov 4, 2025 source file |
| Advocate Christ Medical Center Oak Lawn, IL · (708) 684-8000 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ | $462.50 | $925.00 | $404.23–$740.00 | 50% | Nov 4, 2025 source file |
| Advocate Childrens Hospital Park Ridge Park Ridge, IL FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ | $462.50 | $925.00 | $404.23–$740.00 | 50% | Nov 4, 2025 source file |
| Advocate Condell Medical Center Libertyville, IL · (847) 362-2900 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ | $462.50 | $925.00 | $404.23–$740.00 | 50% | Nov 4, 2025 source file |
| Advocate Good Samaritan Hospital Downers Grove, IL · (630) 275-5900 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ | $462.50 | $925.00 | $404.23–$740.00 | 50% | Nov 4, 2025 source file |
| Advocate Illinois Masonic Medical Center Chicago, IL · (773) 975-1600 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ | $462.50 | $925.00 | $404.23–$740.00 | 50% | Nov 4, 2025 source file |
| Advocate Lutheran General Hospital Park Ridge, IL · (847) 723-2210 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ | $462.50 | $925.00 | $404.23–$740.00 | 50% | Nov 4, 2025 source file |
| Advocate Sherman Hospital Elgin, IL · (847) 742-9800 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ | $462.50 | $925.00 | $404.23–$832.50 | 50% | Nov 4, 2025 source file |
| Advocate Good Shepherd Hospital Barrington, IL · (847) 381-9600 FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ | $462.50 | $925.00 | $404.23–$740.00 | 50% | Nov 4, 2025 source file |
| Advocate Childrens Hospital Oak Lawn Oak Lawn, IL FETAL CHROMOSOMAL ANEUPLOIDY GENOMIC SEQ | $462.50 | $925.00 | $404.23–$740.00 | 50% | Nov 4, 2025 source file |
| Presence Saint Joseph Hospital - Chicago Chicago, IL · (773) 665-3000 HC FETAL CHROMOSOMAL ANEUPLOIDY | $770.55 | $2,335.00 | $759.05–$1,100.62 | 67% | — source file |
| Resilience Healthcare West Suburban Medical Center Oak Park, IL · (708) 383-6200 MaterniT21 PLUS Core+SCA SO | $805.42 | $2,368.88 | $1,539.77 | 66% | Mar 17, 2025 source file |
| Louis A Weiss Memorial Hospital Chicago, IL · (773) 878-8700 MaterniT21 PLUS Core+SCA SO | $805.42 | $2,368.88 | $1,539.77 | 66% | Mar 17, 2025 source file |
| Ingalls Memorial Hospital Harvey, IL · (708) 333-2300 Hc Fetal Chromosomal Aneuploidy Genomic Seq Analys | $1,258.00 | $1,258.00 | — | — | Apr 1, 2026 source file |
| Ingalls Memorial Hospital Harvey, IL · (708) 333-2300 Noncdm Charge Record | $1,258.00 | $1,258.00 | — | — | Apr 1, 2026 source file |
| Northwest Community Hospital Arlington Heights, IL · (847) 618-1000 Hb Fetal Chrmoml Aneuploidy | $1,380.00 | $1,380.00 | — | — | Apr 1, 2026 source file |
Inpatient: lowest $400.00, median $462.50, highest $1,380.00 — a 3.4× difference within the same market.
As an outpatient, the same code is billed by 32 facilities here, median $615.77 — that is the price to compare if you are not being admitted.
Cash or insurance?
At 14 of 14 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at 2 it is below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
NIPT analyzes fragments of fetal DNA that circulate in the mother's blood to screen for Down syndrome (trisomy 21) and trisomies 18 and 13. It can be done from about 10 weeks of pregnancy. It is a screening test, so a positive result needs a diagnostic test to confirm.
What the price covers
The price usually covers the DNA analysis of one blood sample. The blood draw, genetic counseling and any added screens, such as sex chromosomes or microdeletions, may be billed separately.