Botox for migraine cost in Chicago, IL
In Chicago-Naperville-Elgin, IL-IN, 27 hospitals list a cash price for Botox injections for chronic migraine: from $110.19 to $3,988.25, with a median of $251.38. The lowest listed price is at Morris Hospital — $141.19 less than the median here. Across Illinois, the median is $408.80 at 41 hospitals.
- The median here, $251.38, is 51% below the US median of $518.00.
- That is 0.8× Medicare's 2026 national rate for the same service ($313.60).
- 4 of 27 hospitals list a cash price equal to their full list price, with no self-pay discount.
Cash prices at 35 facilities across 26 cities for code 64615, as an outpatient — the setting a self-pay patient normally buys. Collected Nov 9, 2026; the hospital files themselves were last updated between Jan 1, 2025 and Nov 6, 2026.
Lowest$110.19Morris Hospital
Median$251.38half of hospitals charge less
Highest$3,988.25in this market
Difference36.2×highest vs lowest
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Chicago-Naperville-Elgin, IL-IN.
median
Lowest $110.19Highest $4,076.00
one sideboth sides
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list |
|---|---|---|---|---|
| Morris Hospital lowest Morris, IL · (815) 942-2932 Injection of chemical for paralysis of facial and neck nerve muscles on both sides of face File of Oct 27, 2026 · source file | $110.19 | $458.00 | $62.00–$471.74 | 76% |
| MacNeal Hospital Berwyn, IL · (708) 783-9100 Chemodenerv Musc Facial/Trigem/Cerv Migraine File of Mar 31, 2026 · source file | $156.37 | $823.00 | $156.37–$1,139.86 | 81% |
| Gottlieb Memorial Hospital Melrose Park, IL · (708) 681-3200 Chemodenerv Musc Facial/Trigem/Cerv Migraine File of Mar 31, 2026 · source file | $156.37 | $823.00 | $286.17–$2,252.00 | 81% |
| Northwestern Memorial Hospital Chicago, IL · (312) 926-2000 HB Chemodenerv Musc Migraine File of Apr 1, 2026 · source file | $177.10 | $253.00 | $59.20–$623.00 | 30% |
| Northwestern Medicine Valley West Hospital Sandwich, IL · (815) 786-8484 HB Chemodenerv Musc Migraine File of Apr 1, 2026 · source file | $177.10 | $253.00 | $48.07–$253.00 | 30% |
| NorthShore University HealthSystems Glenbrook Hospital Glenview, IL Chemoderv Facial/Trigem/Cerv Muslc Migraine File of Jan 1, 2025 · source file | $178.75 | $275.00 | $37.13–$150.15 | 35% |
| NorthShore University HealthSystems Skokie Hospital Skokie, IL Chemoderv Facial/Trigem/Cerv Muslc Migraine File of Jan 1, 2025 · source file | $178.75 | $275.00 | $37.13–$150.15 | 35% |
| Loyola University Medical Center Maywood, IL · (708) 216-9000 Chemodenerv Musc Facial/Trigem/Cerv Migraine File of Mar 31, 2026 · source file | $189.29 | $823.00 | $286.17–$571.26 | 77% |
| Uchicago Medicine AdventHealth Glenoaks Glendale Heights, IL · (630) 545-8000 HC CHEMODERVATE FACIAL/TRIGEM/CERV MUSC MIGRAINE File of Apr 1, 2026 · source file | $200.00 | $800.00 | — | 75% |
| Uchicago Medicine AdventHealth Bolingbrook Bolingbrook, IL · (630) 312-5000 HC CHEMODERVATE FACIAL/TRIGEM/CERV MUSC MIGRAINE File of Apr 1, 2026 · source file | $200.00 | $800.00 | — | 75% |
| Uchicago Medicine AdventHealth La Grange La Grange, IL · (708) 352-1200 HC CHEMODERVATE FACIAL/TRIGEM/CERV MUSC MIGRAINE File of Apr 1, 2026 · source file | $200.00 | $800.00 | — | 75% |
| Uchicago Medicine AdventHealth Hinsdale Hinsdale, IL · (630) 856-9000 HC CHEMODERVATE FACIAL/TRIGEM/CERV MUSC MIGRAINE File of Apr 1, 2026 · source file | $200.00 | $800.00 | — | 75% |
| John H. Stroger, Jr. Hospital Chicago, IL · (312) 864-6000 PF-CHEMODENERV MUSC MIGRAINE File of Apr 1, 2026 · source file | $239.40 | $342.00 | $129.50–$273.60 | 30% |
| Community First Medical Center Chicago, IL · (773) 282-7000 Injection of chemical for paralysis of facial and neck nerve muscles on both sides of face File of Apr 1, 2026 · source file | $251.38 | $502.75 | $137.25–$607.73 | 50% |
| Saint Joseph Medical Center - Joliet Joliet, IL · (815) 725-7133 CHEMODENERVTN CHRONIC MIGRAINE File of Sep 1, 2026 · source file | $327.00 | $773.00 | $126.40–$773.00 | 58% |
| Endeavor Health Highland Park Hospital Highland Park, IL CHEMODERV FACIAL/TRIGEM/CERV MUSLC MIGRAINE File of Apr 1, 2026 · source file | $339.00 | $339.00 | — | — |
| Swedish Covenant Health Chicago, IL · (773) 878-8200 CHEMODERV FACIAL/TRIGEM/CERV MUSLC MIGRAINE File of Apr 1, 2026 · source file | $339.00 | $339.00 | — | — |
| Northshore University Healthsystem - Evanston Hospital Evanston, IL · (847) 570-2000 CHEMODERV FACIAL/TRIGEM/CERV MUSLC MIGRAINE File of Apr 1, 2026 · source file | $339.00 | $339.00 | — | — |
| Presence Saint Joseph Hospital - Chicago Chicago, IL · (773) 665-3000 HC CHEMODENERV MUSC MIGRAINE File of Jan 1, 2026 · source file | $350.79 | $1,063.00 | $499.61 | 67% |
| Northwestern Lake Forest Hospital Lake Forest, IL · (847) 234-5600 HB Chemodenerv Musc Migraine File of Apr 1, 2026 · source file | $436.10 | $623.00 | $103.42–$623.00 | 30% |
| Northwestern Medicine Central DuPage Hospital Winfield, IL · (630) 682-1600 HB Chemodenerv Musc Migraine File of Apr 1, 2026 · source file | $436.10 | $623.00 | $42.99–$623.00 | 30% |
| Northwestern Medicine McHenry Hospital McHenry, IL · (815) 344-5000 HB Chemodenerv Musc Migraine File of Apr 1, 2026 · source file | $436.10 | $623.00 | $120.24–$623.00 | 30% |
| John H. Stroger, Jr. Hospital one side Chicago, IL · (312) 864-6000 BOTOX, FACE AND NECK, LEFT File of Apr 1, 2026 · source file | $548.80 | $784.00 | $136.76–$627.20 | 30% |
| Methodist Hospital-Southlake Merrillville, IN · (219) 886-4000 Chemodenerv Musc Migraine File of Aug 18, 2026 · source file | $691.60 | $988.00 | $63.99–$1,118.13 | 30% |
| The Methodist Hospitals Gary, IN · (219) 886-4000 Chemodenerv Musc Migraine File of Aug 18, 2026 · source file | $691.60 | $988.00 | $63.99–$1,118.13 | 30% |
| Northshore University Healthsystem - Evanston Hospital Evanston, IL · (847) 570-2000 HB CHEMODERV FACIAL/TRIGEM/CERV MUSLC MIGRAINE File of Apr 1, 2026 · source file | $808.00 | $808.00 | — | — |
| Endeavor Health Highland Park Hospital Highland Park, IL HB CHEMODERV FACIAL/TRIGEM/CERV MUSLC MIGRAINE File of Apr 1, 2026 · source file | $808.00 | $808.00 | — | — |
| Swedish Covenant Health Chicago, IL · (773) 878-8200 HB CHEMODERV FACIAL/TRIGEM/CERV MUSLC MIGRAINE File of Apr 1, 2026 · source file | $808.00 | $808.00 | — | — |
| Northwest Community Hospital Arlington Heights, IL · (847) 618-1000 Hb Chemodenerv Musc Migraine File of Apr 1, 2026 · source file | $808.00 | $808.00 | — | — |
| Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, IL · (312) 227-4000 H CHEMODNRVTJ MUSC MUSC INNERVATED FACIAL BIL+1 more line at this price File of Sep 1, 2026 · source file | $1,054.90 | $1,507.00 | $256.19–$1,431.65 | 30% |
| Northwestern Medicine Kishwaukee Hospital DeKalb, IL · (815) 756-1521 HB Chemodenerv Musc Migraine File of Apr 1, 2026 · source file | $3,988.25 | $5,697.50 | — | 30% |
| Gottlieb Memorial Hospital both sides Melrose Park, IL · (708) 681-3200 Chemodenerv Musc Fac, Trigem, Cerv, Acc Nrv Bilat File of Mar 31, 2026 · source file | $156.37 | $823.00 | $286.17–$2,252.00 | 81% |
| MacNeal Hospital both sides Berwyn, IL · (708) 783-9100 Chemodenerv Musc Fac, Trigem, Cerv, Acc Nrv Bilat File of Mar 31, 2026 · source file | $156.37 | $823.00 | $156.37–$1,139.86 | 81% |
| Loyola University Medical Center both sides Maywood, IL · (708) 216-9000 Chemodenerv Musc Fac, Trigem, Cerv, Acc Nrv Bilat File of Mar 31, 2026 · source file | $189.29 | $823.00 | $286.17–$571.26 | 77% |
| Advocate Childrens Hospital Park Ridge both sides Park Ridge, IL DENERVATION MUSCLES BILAT MIGRAINE File of Nov 6, 2026 · source file | $492.50 | $985.00 | $388.09–$4,270.00 | 50% |
| Advocate Christ Medical Center both sides Oak Lawn, IL · (708) 684-8000 DENERVATION MUSCLES BILAT MIGRAINE File of Nov 3, 2026 · source file | $492.50 | $985.00 | $388.09–$4,270.00 | 50% |
| Advocate Lutheran General Hospital both sides Park Ridge, IL · (847) 723-2210 DENERVATION MUSCLES BILAT MIGRAINE File of Nov 3, 2026 · source file | $492.50 | $985.00 | $388.09–$4,270.00 | 50% |
| Advocate Sherman Hospital both sides Elgin, IL · (847) 742-9800 DENERVATION MUSCLES BILAT MIGRAINE File of Nov 3, 2026 · source file | $492.50 | $985.00 | $365.44–$3,270.00 | 50% |
| Advocate Illinois Masonic Medical Center both sides Chicago, IL · (773) 975-1600 DENERVATION MUSCLES BILAT MIGRAINE File of Nov 3, 2026 · source file | $492.50 | $985.00 | $388.09–$4,270.00 | 50% |
| Advocate Childrens Hospital Oak Lawn both sides Oak Lawn, IL DENERVATION MUSCLES BILAT MIGRAINE File of Nov 3, 2026 · source file | $492.50 | $985.00 | $388.09–$4,270.00 | 50% |
| John H. Stroger, Jr. Hospital both sides Chicago, IL · (312) 864-6000 BOTOX, FACE AND NECK BILATERAL File of Apr 1, 2026 · source file | $548.80 | $784.00 | $118.26–$627.20 | 30% |
| Edward Hospital both sides Naperville, IL · (630) 527-3000 HC CHEMODENERVATION MUSCLE INNERV FACIAL BILAT File of Apr 1, 2026 · source file | $808.00 | $808.00 | — | — |
| The University of Chicago Medical Center both sides Chicago, IL · (773) 702-9785 Hc Chemodenervat Muscle(S); Innervated By Facial/Trigeminal/Cervical Spnal & Accessory Nerves Bilat- File of Apr 1, 2026 · source file | $1,008.00 | $1,008.00 | — | — |
| The University of Chicago Medical Center both sides Chicago, IL · (773) 702-9785 Hc Chemodenervat Muscle(S); Innervated By Facial/Trigeminal/Cervical Spnal & Accessory Nerves Bilat File of Apr 1, 2026 · source file | $4,076.00 | $4,076.00 | — | — |
Hospital The hospital that published the price, its city and the line exactly as written in its price file.
Cash price The hospital's own price for a patient paying without insurance (“discounted cash” in its price file). Hospitals must publish it under federal law, 45 CFR 180.50. Call to confirm it before booking. More
List price The hospital's full chargemaster price (“gross charge”) before any discount. Almost nobody pays it; the gap to the cash price shows what the self-pay discount is worth. More
Insurers pay The lowest and highest rates this hospital has agreed with insurance plans for the same item, from its price file. If the cash price is below what your plan pays and you have not met your deductible, paying cash can cost you less. More
Off list How much lower the cash price is than the list price.
At or below Medicare This cash price is at or below what Medicare pays a hospital for the same service, which is unusually low. It is what the hospital's file says; confirm it and what it includes before booking. More
No cash discount This line's cash price equals the hospital's full list price. Many hospitals still reduce bills for uninsured patients: ask the billing office for its self-pay discount in writing. More
Outpatient: lowest $110.19, median $251.38, highest $3,988.25 — a 36.2× difference within the same market.
Both sides : lowest $156.37, median $492.50, highest $1,008.00 — a 6.4× difference within the same market.
The two groups are not comparable and are not averaged together: a
price for both sides of the body covers twice the work. Merging them is how a single
published "median" ends up far above what one side actually costs.
As an inpatient, the same code is billed by 12 facilities here, median $219.70. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 16 of 18 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at 3 it is below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What Botox for migraine is, what the price covers and why prices differ: Botox for migraine explained.