Botox for migraine cost in Chicago, IL
In Chicago-Naperville-Elgin, IL-IN, 25 hospitals list a cash price for Botox injections for chronic migraine: from $156.37 to $3,988.25, with a median of $339.00. The lowest listed price is at Gottlieb Memorial Hospital — $182.63 less than the median here. Across Illinois, the median is $251.38 at 29 hospitals.
Cash prices at 32 facilities across 24 cities for code 64615, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 23, 2026; the hospital files themselves were last updated between Nov 4, 2025 and Apr 1, 2026.
Lowest$156.37Gottlieb Memorial Hospital
Median$339.00half pay less
Highest$3,988.25in this market
Difference25.5×highest vs lowest
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Chicago-Naperville-Elgin, IL-IN.
median
Lowest $156.37Highest $4,076.00
one sideboth sides
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list | File date |
|---|---|---|---|---|---|
| Gottlieb Memorial Hospital lowest Melrose Park, IL · (708) 681-3200 Chemodenerv Musc Facial/Trigem/Cerv Migraine | $156.37 | $823.00 | $286.17–$2,252.00 | 81% | Mar 31, 2026 source file |
| Northwestern Medicine Valley West Hospital Sandwich, IL · (815) 786-8484 HB Chemodenerv Musc Migraine | $177.10 | $253.00 | $48.07–$253.00 | 30% | Apr 1, 2026 source file |
| NorthShore University HealthSystems Glenbrook Hospital Glenview, IL Chemoderv Facial/Trigem/Cerv Muslc Migraine | $178.75 | $275.00 | $37.13–$150.15 | 35% | — source file |
| NorthShore University HealthSystems Highland Park Hospital Highland Park, IL Chemoderv Facial/Trigem/Cerv Muslc Migraine | $178.75 | $275.00 | $37.13–$150.15 | 35% | — source file |
| NorthShore University HealthSystems Evanston Hospital Evanson, IL · (847) 570-2000 Chemoderv Facial/Trigem/Cerv Muslc Migraine | $178.75 | $275.00 | $37.13–$150.15 | 35% | — source file |
| NorthShore University HealthSystems Skokie Hospital Skokie, IL Chemoderv Facial/Trigem/Cerv Muslc Migraine | $178.75 | $275.00 | $37.13–$150.15 | 35% | — source file |
| Loyola University Medical Center Maywood, IL · (708) 216-9000 Chemodenerv Musc Facial/Trigem/Cerv Migraine | $189.29 | $823.00 | $286.17–$571.26 | 77% | Mar 31, 2026 source file |
| Uchicago Medicine AdventHealth La Grange La Grange, IL · (708) 352-1200 HC CHEMODERVATE FACIAL/TRIGEM/CERV MUSC MIGRAINE | $200.00 | $800.00 | — | 75% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth Bolingbrook Bolingbrook, IL · (630) 312-5000 HC CHEMODERVATE FACIAL/TRIGEM/CERV MUSC MIGRAINE | $200.00 | $800.00 | — | 75% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth Bolingbrook Bolingbrook, IL · (630) 312-5000 HC CHEMODERVATE FACIAL/TRIGEM/CERV MUSC MIGRAINE | $200.00 | $800.00 | — | 75% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth Glenoaks Glendale Heights, IL · (630) 545-8000 HC CHEMODERVATE FACIAL/TRIGEM/CERV MUSC MIGRAINE | $200.00 | $800.00 | — | 75% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth Glenoaks Glendale Heights, IL · (630) 545-8000 HC CHEMODERVATE FACIAL/TRIGEM/CERV MUSC MIGRAINE | $200.00 | $800.00 | — | 75% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth Hinsdale Hinsdale, IL · (630) 856-9000 HC CHEMODERVATE FACIAL/TRIGEM/CERV MUSC MIGRAINE | $200.00 | $800.00 | — | 75% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth Hinsdale Hinsdale, IL · (630) 856-9000 HC CHEMODERVATE FACIAL/TRIGEM/CERV MUSC MIGRAINE | $200.00 | $800.00 | — | 75% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth La Grange La Grange, IL · (708) 352-1200 HC CHEMODERVATE FACIAL/TRIGEM/CERV MUSC MIGRAINE | $200.00 | $800.00 | — | 75% | Apr 1, 2026 source file |
| Community First Medical Center Chicago, IL · (773) 282-7000 Injection of chemical for paralysis of facial and neck nerve muscles on both sides of face | $251.38 | $502.75 | $137.25–$607.73 | 50% | Apr 1, 2026 source file |
| Endeavor Health Clinical Operations Highland Park, IL CHEMODERV FACIAL/TRIGEM/CERV MUSLC MIGRAINE | $339.00 | $339.00 | — | — | Apr 1, 2026 source file |
| Swedish Covenant Health Chicago, IL · (773) 878-8200 CHEMODERV FACIAL/TRIGEM/CERV MUSLC MIGRAINE | $339.00 | $339.00 | — | — | Apr 1, 2026 source file |
| Northshore University Healthsystem - Evanston Hospital Evanston, IL · (847) 570-2000 CHEMODERV FACIAL/TRIGEM/CERV MUSLC MIGRAINE | $339.00 | $339.00 | — | — | Apr 1, 2026 source file |
| Presence Saint Joseph Hospital - Chicago Chicago, IL · (773) 665-3000 HC CHEMODENERV MUSC MIGRAINE | $350.79 | $1,063.00 | $499.61 | 67% | — source file |
| Northwestern Lake Forest Hospital Lake Forest, IL · (847) 234-5600 HB Chemodenerv Musc Migraine | $436.10 | $623.00 | $103.42–$623.00 | 30% | Apr 1, 2026 source file |
| Northwestern Medicine McHenry Hospital McHenry, IL · (815) 344-5000 HB Chemodenerv Musc Migraine | $436.10 | $623.00 | $120.24–$623.00 | 30% | Apr 1, 2026 source file |
| Northwestern Medicine Central DuPage Hospital Winfield, IL · (630) 682-1600 HB Chemodenerv Musc Migraine | $436.10 | $623.00 | $42.99–$623.00 | 30% | Apr 1, 2026 source file |
| The Methodist Hospitals Merrillville, IN Chemodenerv Musc Migraine | $691.60 | $988.00 | $63.99–$1,118.13 | 30% | — source file |
| The Methodist Hospitals Gary, IN · (219) 886-4000 Chemodenerv Musc Migraine | $691.60 | $988.00 | $63.99–$1,118.13 | 30% | — source file |
| Northshore University Healthsystem - Evanston Hospital Evanston, IL · (847) 570-2000 HB CHEMODERV FACIAL/TRIGEM/CERV MUSLC MIGRAINE | $808.00 | $808.00 | — | — | Apr 1, 2026 source file |
| Swedish Covenant Health Chicago, IL · (773) 878-8200 HB CHEMODERV FACIAL/TRIGEM/CERV MUSLC MIGRAINE | $808.00 | $808.00 | — | — | Apr 1, 2026 source file |
| Endeavor Health Clinical Operations Highland Park, IL HB CHEMODERV FACIAL/TRIGEM/CERV MUSLC MIGRAINE | $808.00 | $808.00 | — | — | Apr 1, 2026 source file |
| Northwest Community Hospital Arlington Heights, IL · (847) 618-1000 Hb Chemodenerv Musc Migraine | $808.00 | $808.00 | — | — | Apr 1, 2026 source file |
| Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, IL · (312) 227-4000 H IR 64615 CHEMODNRVTJ MUSC MUSC INNERVATED FACIAL BIL | $844.20 | $1,206.00 | $205.02–$14,756.00 | 30% | — source file |
| Ann & Robert H. Lurie Children's Hospital of Chicago Chicago, IL · (312) 227-4000 H CHEMODNRVTJ MUSC MUSC INNERVATED FACIAL BIL | $844.20 | $1,206.00 | $205.02–$14,756.00 | 30% | — source file |
| The University of Chicago Medical Center Chicago, IL · (773) 702-9785 Pr Chemodervate Facial/Trigem/Cerv Musc Migraine-Pbb | $3,190.00 | $3,190.00 | — | — | Apr 1, 2026 source file |
| Northwestern Medicine Kishwaukee Hospital DeKalb, IL · (815) 756-1521 HB Chemodenerv Musc Migraine | $3,988.25 | $5,697.50 | — | 30% | Apr 1, 2026 source file |
| Gottlieb Memorial Hospital both sides Melrose Park, IL · (708) 681-3200 Chemodenerv Musc Fac, Trigem, Cerv, Acc Nrv Bilat | $156.37 | $823.00 | $286.17–$2,252.00 | 81% | Mar 31, 2026 source file |
| Loyola University Medical Center both sides Maywood, IL · (708) 216-9000 Chemodenerv Musc Fac, Trigem, Cerv, Acc Nrv Bilat | $189.29 | $823.00 | $286.17–$571.26 | 77% | Mar 31, 2026 source file |
| Advocate Childrens Hospital Oak Lawn both sides Oak Lawn, IL DENERVATION MUSCLES BILAT MIGRAINE | $375.00 | $750.00 | $295.50–$6,291.00 | 50% | Nov 4, 2025 source file |
| Advocate Christ Medical Center both sides Oak Lawn, IL · (708) 684-8000 DENERVATION MUSCLES BILAT MIGRAINE | $375.00 | $750.00 | $295.50–$6,291.00 | 50% | Nov 4, 2025 source file |
| Advocate Sherman Hospital both sides Elgin, IL · (847) 742-9800 DENERVATION MUSCLES BILAT MIGRAINE | $470.00 | $940.00 | $348.74–$4,116.00 | 50% | Nov 4, 2025 source file |
| Advocate Childrens Hospital Park Ridge both sides Park Ridge, IL DENERVATION MUSCLES BILAT MIGRAINE | $505.00 | $1,010.00 | $397.94–$6,291.00 | 50% | Nov 4, 2025 source file |
| Advocate Lutheran General Hospital both sides Park Ridge, IL · (847) 723-2210 DENERVATION MUSCLES BILAT MIGRAINE | $505.00 | $1,010.00 | $397.94–$6,291.00 | 50% | Nov 4, 2025 source file |
| Advocate Illinois Masonic Medical Center both sides Chicago, IL · (773) 975-1600 DENERVATION MUSCLES BILAT MIGRAINE | $515.00 | $1,030.00 | $405.82–$6,291.00 | 50% | Nov 4, 2025 source file |
| Edward Hospital both sides Naperville, IL · (630) 527-3000 HC CHEMODENERVATION MUSCLE INNERV FACIAL BILAT | $808.00 | $808.00 | — | — | Apr 1, 2026 source file |
| The University of Chicago Medical Center both sides Chicago, IL · (773) 702-9785 Hc Chemodenervat Muscle(S); Innervated By Facial/Trigeminal/Cervical Spnal & Accessory Nerves Bilat- | $1,008.00 | $1,008.00 | — | — | Apr 1, 2026 source file |
| The University of Chicago Medical Center both sides Chicago, IL · (773) 702-9785 Hc Chemodenervat Muscle(S); Innervated By Facial/Trigeminal/Cervical Spnal & Accessory Nerves Bilat | $4,076.00 | $4,076.00 | — | — | Apr 1, 2026 source file |
Outpatient: lowest $156.37, median $339.00, highest $3,988.25 — a 25.5× difference within the same market.
Both sides : lowest $156.37, median $487.50, highest $1,008.00 — a 6.4× difference within the same market.
The two groups are not comparable and are not averaged together: a
price for both sides of the body covers twice the work. Merging them is how a single
published "median" ends up far above what one side actually costs.
As an inpatient, the same code is billed by 14 facilities here, median $200.00. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 11 of 15 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at 3 it is below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
This code covers injecting botulinum toxin into muscles of the head and neck to prevent chronic migraine, usually every 12 weeks.
What the price covers
The price usually covers the injection. The steroid or other medicine may be billed separately.