Hepatitis B vaccine (Heplisav-B) cost in Boston, MA — inpatient
In Boston-Cambridge-Newton, MA-NH, 7 hospitals list a cash price for hepatitis B vaccine, adult, 2-dose schedule (Heplisav-B) as an inpatient: from $108.68 to $331.17, with a median of $300.00. The lowest listed price is at Boston Medical Center Brighton — $191.32 less than the median here. Across Massachusetts, the median is $315.59 at 14 hospitals.
Cash prices at 7 facilities across 5 cities for code 90739, as an inpatient (admitted to hospital) . Collected Sep 27, 2026; the hospital files themselves were last updated between Jan 28, 2026 and Jan 28, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Boston-Cambridge-Newton, MA-NH.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list | File date |
|---|---|---|---|---|---|
| Boston Medical Center Brighton lowest Boston, MA · (617) 789-3000 HC Hepatitis B Vaccine Adult 2 Dose Im | $108.68 | $241.50 | $159.68–$475.07 | 55% | — source file |
| Signature Healthcare Brockton Hospital Brockton, MA · (508) 941-7000 HEPLISAV-B 20mcg (HEP B VACC) | $130.83 | $186.90 | — | 30% | Jan 28, 2026 source file |
| Boston Medical Center Boston, MA · (617) 638-8000 HEPATITIS B VACCINE 20 MCG/0.5 ML-ADJUVANT CPG 1018 (PF) IM SYRINGE | $152.87 | $339.70 | $113.27–$512.54 | 55% | — source file |
| Boston Medical Center Boston, MA · (617) 638-8000 HC Hepatitis B Vaccine Adult 2 Dose Im | $184.05 | $409.00 | $113.27–$512.54 | 55% | — source file |
| Cambridge Health Alliance Cambridge, MA · (617) 665-1000 HC Hepb Vaccine Adult 2 Dose Schedule for Im Use | $300.00 | $300.00 | $142.44–$377.25 | — | — source file |
| Tufts Medical Center Boston, MA · (617) 636-5000 HEPATITIS B VACCINE 20 MCG/0.5 ML-ADJUVANT CPG 101 | $331.17 | $473.10 | $124.24–$473.10 | 30% | — source file |
| Melrosewakefield Healthcare Melrose, MA · (781) 979-3000 HEPATITIS B VACCINE 20 MCG/0.5 ML-ADJUVANT CPG 101 | $331.17 | $473.10 | $146.99–$530.75 | 30% | — source file |
| Lowell General Hospital Lowell, MA · (978) 937-6000 HEPATITIS B VACCINE 20 MCG/0.5 ML-ADJUVANT CPG 101 | $331.17 | $473.10 | $139.53–$473.10 | 30% | — source file |
| Lowell General Hospital Lowell, MA · (978) 937-6000 HC Pbb Imm Hepb Vaccine Adult 2 Dose Schedule for | $634.16 | $905.94 | $139.53–$905.94 | 30% | — source file |
| Tufts Medical Center Boston, MA · (617) 636-5000 HC Pbb Imm Hepb Vaccine Adult 2 Dose Schedule for | $634.16 | $905.94 | $0.01–$905.94 | 30% | — source file |
| Melrosewakefield Healthcare Melrose, MA · (781) 979-3000 HC Pbb Imm Hepb Vaccine Adult 2 Dose Schedule for | $634.16 | $905.94 | $146.99–$979.59 | 30% | — source file |
Inpatient: lowest $108.68, median $300.00, highest $331.17 — a 3.0× difference within the same market.
As an outpatient, the same code is billed by 10 facilities here, median $315.59 — that is the price to compare if you are not being admitted.
Cash or insurance?
At 6 of 6 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at 1 it is below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
Heplisav-B is a hepatitis B vaccine for adults that needs only two doses, one month apart, instead of three over six months.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).