Mpox vaccine (Jynneos) cost in Chicago, IL
In Chicago-Naperville-Elgin, IL-IN, 5 hospitals list a cash price for mpox and smallpox vaccine (Jynneos), 2-dose schedule: from $157.51 to $1,085.40, with a median of $190.67. The lowest listed price is at Gottlieb Memorial Hospital and 1 other hospital — $33.16 less than the median here. Across Illinois, the median is $388.80 at 13 hospitals.
Cash prices at 5 facilities across 5 cities for code 90611, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 27, 2026; the hospital files themselves were last updated between Mar 31, 2026 and Apr 1, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Chicago-Naperville-Elgin, IL-IN.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list | File date |
|---|---|---|---|---|---|
| Gottlieb Memorial Hospital lowest Melrose Park, IL · (708) 681-3200 HC Smallpox/Monkeypox Vaccine Preservative Free 0.5 Ml Dose Susp | $157.51 | $829.00 | $249.53–$694.70 | 81% | Mar 31, 2026 source file |
| Gottlieb Memorial Hospital lowest Melrose Park, IL · (708) 681-3200 HC Smallpox/Monkeypox Vaccine Preservative Free 0.5 Ml Dose Susp | $157.51 | $829.00 | $249.53–$694.70 | 81% | Mar 31, 2026 source file |
| MacNeal Hospital lowest Berwyn, IL · (708) 783-9100 HC Smallpox/Monkeypox Vaccine Preservative Free 0.5 Ml Dose Susp | $157.51 | $829.00 | $157.51–$1,148.17 | 81% | Mar 31, 2026 source file |
| Loyola University Medical Center Maywood, IL · (708) 216-9000 HC Smallpox/Monkeypox Vaccine Preservative Free 0.5 Ml Dose Susp | $190.67 | $829.00 | $0.01–$36.28 | 77% | Mar 31, 2026 source file |
| Loyola University Medical Center Maywood, IL · (708) 216-9000 HC Smallpox/Monkeypox Vaccine Preservative Free 0.5 Ml Dose Susp | $190.67 | $829.00 | $287.66–$873.77 | 77% | Mar 31, 2026 source file |
| Northwestern Memorial Hospital Chicago, IL · (312) 926-2000 HB Smallpox&Monkeypox Vacc 0.5ml Dos for Subq Use, Jynneos | $374.50 | $535.00 | $103.79–$535.00 | 30% | Apr 1, 2026 source file |
| Uchicago Medicine AdventHealth Hinsdale Hinsdale, IL · (630) 856-9000 SMALLPOX,MPOX LIVE VACCINE(PF) 0.5X TO 3.95X 10EXP8/0.5 ML SUBCUT SUSP | $1,085.40 | $1,809.00 | — | 40% | Apr 1, 2026 source file |
Outpatient: lowest $157.51, median $190.67, highest $1,085.40 — a 6.9× difference within the same market.
As an inpatient, the same code is billed by 4 facilities here, median $174.09. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 3 of 4 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at 1 it is below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
Jynneos protects against mpox (monkeypox) and smallpox. It is two doses four weeks apart, recommended for people at higher risk of mpox exposure.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).
8 rows held back from this comparison
They are priced below $1 or below a tenth of the national median for code 90611 ($377.42). Such a line is almost always a physician's fee billed separately, an assistant's share or a placeholder — a real charge, but not the price of the procedure itself.
| Swedish Covenant Health Chicago, ILSMALLPOX & MONKEYPOX VACC LIVE PF 0.5ML DOSE SUBQ | $0.01 | file |
| Endeavor Health Highland Park Hospital Highland Park, ILSMALLPOX & MONKEYPOX VACC LIVE PF 0.5ML DOSE SUBQ | $0.01 | file |
| NorthShore University HealthSystems Skokie Hospital Skokie, ILSmallpox & Monkeypox Vacc Live Pf 0.5ml Dose Subq | $0.01 | file |
| NorthShore University HealthSystems Glenbrook Hospital Glenview, ILSmallpox & Monkeypox Vacc Live Pf 0.5ml Dose Subq | $0.01 | file |
| The University of Chicago Medical Center Chicago, ILPr Smallpox&Monkeypox Vacc 0.5Ml Dos For Subq Use | $0.01 | file |
| The University of Chicago Medical Center Chicago, ILNDC Description Not Available | $0.01 | file |
| The University of Chicago Medical Center Chicago, ILJynneos: 20 Vial In 1 Carton (50632-001-02) / .5 Ml In 1 Vial (50632-001-01) | $0.01 | file |
| Northshore University Healthsystem - Evanston Hospital Evanston, ILSMALLPOX & MONKEYPOX VACC LIVE PF 0.5ML DOSE SUBQ | $0.01 | file |