NIPT prenatal DNA test cost in Philadelphia, PA — inpatient
In Philadelphia-Camden-Wilmington, PA-NJ-DE-MD, 12 hospitals list a cash price for prenatal cell-free DNA screen for trisomy 21, 18 and 13 (NIPT) as an inpatient: from $1,440.80 to $2,429.05, with a median of $2,072.20. The lowest listed price is at Paoli Hospital and 4 other hospitals — $631.40 less than the median here. Across Pennsylvania, the median is $2,072.20 at 32 hospitals.
Cash prices at 12 facilities across 12 cities for code 81420, as an inpatient (admitted to hospital) . Collected Sep 23, 2026; the hospital files themselves were last updated between Mar 24, 2026 and Apr 1, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Philadelphia-Camden-Wilmington, PA-NJ-DE-MD.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list | File date |
|---|---|---|---|---|---|
| Paoli Hospital lowest Paoli, PA · (610) 648-1000 Hc Qnatal Advanced Fetal Chromosomal Aneuploidy Genomic Seq Analys | $1,440.80 | $3,602.00 | — | 60% | Apr 1, 2026 source file |
| The Bryn Mawr Hospital lowest Bryn Mawr, PA · (610) 526-3000 Hc Qnatal Advanced Fetal Chromosomal Aneuploidy Genomic Seq Analys | $1,440.80 | $3,602.00 | — | 60% | — source file |
| Lankenau Medical Center lowest Wynnewood, PA · (610) 645-2000 Hc Qnatal Advanced Fetal Chromosomal Aneuploidy Genomic Seq Analys | $1,440.80 | $3,602.00 | — | 60% | Apr 1, 2026 source file |
| Riddle Memorial Hospital lowest Media, PA · (610) 566-9400 Hc Qnatal Advanced Fetal Chromosomal Aneuploidy Genomic Seq Analys | $1,440.80 | $3,602.00 | — | 60% | Apr 1, 2026 source file |
| Bryn Mawr Rehabilitation Hospital lowest Malvern, PA Hc Qnatal Advanced Fetal Chromosomal Aneuploidy Genomic Seq Analys | $1,440.80 | $3,602.00 | — | 60% | — source file |
| Riddle Memorial Hospital Media, PA · (610) 566-9400 Hc Qnatal, Non Invasive Prenatal | $1,469.20 | $3,673.00 | — | 60% | Apr 1, 2026 source file |
| Lankenau Medical Center Wynnewood, PA · (610) 645-2000 Hc Qnatal, Non Invasive Prenatal | $1,469.20 | $3,673.00 | — | 60% | Apr 1, 2026 source file |
| Paoli Hospital Paoli, PA · (610) 648-1000 Hc Qnatal, Non Invasive Prenatal | $1,469.20 | $3,673.00 | — | 60% | Apr 1, 2026 source file |
| The Bryn Mawr Hospital Bryn Mawr, PA · (610) 526-3000 Hc Qnatal, Non Invasive Prenatal | $1,469.20 | $3,673.00 | — | 60% | — source file |
| Bryn Mawr Rehabilitation Hospital Malvern, PA Hc Qnatal, Non Invasive Prenatal | $1,469.20 | $3,673.00 | — | 60% | — source file |
| Mercy Fitzgerald Hospital Darby, PA · (215) 237-4000 HC Warde Analysis Genomic Sequence Fetal Chromosomal Aneuploidy | $2,072.20 | $3,188.00 | $757.15–$4,421.19 | 35% | Mar 31, 2026 source file |
| Mercy Fitzgerald Hospital Darby, PA · (215) 237-4000 HC Quest Analysis Genomic Sequence Fetal Chromosomal Aneuploidy | $2,072.20 | $3,188.00 | $757.15–$4,421.19 | 35% | Mar 31, 2026 source file |
| Nazareth Hospital Philadelphia, PA · (215) 335-6000 HC Warde Analysis Genomic Sequence Fetal Chromosomal Aneuploidy | $2,072.20 | $3,188.00 | $473.55–$5,655.65 | 35% | Mar 31, 2026 source file |
| Inspira Medical Center Mullica Hill Mullica Hill, NJ Fetal Chromosomal Aneuploidy | $2,395.43 | $2,395.43 | — | — | Mar 24, 2026 source file |
| Inspira Medical Center Mullica Hill Mullica Hill, NJ MaterniT21 PLUS Core | $2,395.43 | $2,395.43 | — | — | Mar 24, 2026 source file |
| Inspira Health Center Woodbury Woodbury, NJ MaterniT21 PLUS Core | $2,395.43 | $2,395.43 | — | — | Mar 24, 2026 source file |
| Inspira Health Center Woodbury Woodbury, NJ Fetal Chromosomal Aneuploidy | $2,395.43 | $2,395.43 | — | — | Mar 24, 2026 source file |
| Inspira Medical Center Mannington Salem, NJ Fetal Chromosomal Aneuploidy | $2,395.43 | $2,395.43 | — | — | Mar 24, 2026 source file |
| Inspira Medical Center Mannington Salem, NJ MaterniT21 PLUS Core | $2,395.43 | $2,395.43 | — | — | Mar 24, 2026 source file |
| Inspira Medical Center Elmer Elmer, NJ · (856) 363-1000 Fetal Chromosomal Aneuploidy | $2,395.43 | $2,395.43 | — | — | Mar 24, 2026 source file |
| Inspira Medical Center Elmer Elmer, NJ · (856) 363-1000 MaterniT21 PLUS Core | $2,395.43 | $2,395.43 | — | — | Mar 24, 2026 source file |
| St. Francis Hospital Wilmington, DE · (302) 421-4100 HC Quest Analysis Genomic Sequence Fetal Chromosomal Aneuploidy | $2,429.05 | $3,737.00 | $743.87–$5,076.22 | 35% | Mar 31, 2026 source file |
Inpatient: lowest $1,440.80, median $2,072.20, highest $2,429.05 — a 1.7× difference within the same market.
As an outpatient, the same code is billed by 18 facilities here, median $1,440.80 — that is the price to compare if you are not being admitted.
Cash or insurance?
At 3 of 3 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
NIPT analyzes fragments of fetal DNA that circulate in the mother's blood to screen for Down syndrome (trisomy 21) and trisomies 18 and 13. It can be done from about 10 weeks of pregnancy. It is a screening test, so a positive result needs a diagnostic test to confirm.
What the price covers
The price usually covers the DNA analysis of one blood sample. The blood draw, genetic counseling and any added screens, such as sex chromosomes or microdeletions, may be billed separately.