Hepatitis B vaccine (Heplisav-B) cost in Portland, ME
In Portland-South Portland, ME, 2 hospitals list a cash price for hepatitis B vaccine, adult, 2-dose schedule (Heplisav-B): from $157.20 to $1,585.45, with a median of $871.33. The lowest listed price is at York Hospital — $714.13 less than the median here. Across Maine, the median is $189.79 at 4 hospitals.
Cash prices at 2 facilities across 2 cities for code 90739, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 23, 2026; the hospital files themselves were last updated between Sep 9, 2025 and Sep 9, 2025.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Portland-South Portland, ME.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list |
|---|---|---|---|---|
| York Hospital lowest York, ME · (207) 351-2478 HEPB VACCINE 2 DOSE ADULT IM source file | $157.20 | $262.00 | — | 40% |
| MaineHealth Maine Medical Center Portland, ME · (207) 662-0111 HEPATITIS B VAC RECOMB ADJ 20 MCG/0.5ML IM SOSY File of Sep 9, 2025 · source file | $1,585.45 | $1,585.45 | $177.56–$1,490.32 | — |
Outpatient: lowest $157.20, median $871.33, highest $1,585.45 — a 10.1× difference within the same market.
As an inpatient, the same code is billed by 2 facilities here, median $871.33. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At the one hospital here that publishes insurer rates for this code, the cash price is not below the highest rate a health plan has negotiated. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
Heplisav-B is a hepatitis B vaccine for adults that needs only two doses, one month apart, instead of three over six months.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).