Hepatitis B vaccine (Heplisav-B) cost in Des Moines, IA
In Des Moines-West Des Moines, IA, 4 hospitals list a cash price for hepatitis B vaccine, adult, 2-dose schedule (Heplisav-B): from $165.34 to $502.00, with a median of $318.50. The lowest listed price is at UnityPoint Health - Des Moines Iowa Methodist Medical — $153.16 less than the median here. Across Iowa, the median is $306.24 at 32 hospitals.
Cash prices at 4 facilities across 3 cities for code 90739, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 23, 2026; the hospital files themselves were last updated between Jan 28, 2026 and Mar 31, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Des Moines-West Des Moines, IA.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list | File date |
|---|---|---|---|---|---|
| UnityPoint Health - Des Moines Iowa Methodist Medical lowest Des Moines, IA · (515) 343-1000 HC HEPB VACC 2 DOSE ADULT IM | $165.34 | $206.67 | $42.16–$186.43 | 20% | Jan 28, 2026 source file |
| UnityPoint Health - Des Moines Iowa Methodist Medical lowest Des Moines, IA · (515) 343-1000 HC HEPB VACC 2 DOSE ADULT IM | $165.34 | $206.67 | $42.16–$186.43 | 20% | Jan 28, 2026 source file |
| UnityPoint Health - Des Moines Iowa Methodist Medical Des Moines, IA · (515) 343-1000 HEPATITIS B VAC RECOMB ADJ 20 MCG/0.5ML IM SOSY | $306.24 | $382.80 | $78.09–$187.57 | 20% | Jan 28, 2026 source file |
| UnityPoint Health - Des Moines Iowa Methodist Medical Des Moines, IA · (515) 343-1000 HEPATITIS B VAC RECOMB ADJ 20 MCG/0.5ML IM SOSY | $306.24 | $382.80 | $78.09–$187.57 | 20% | Jan 28, 2026 source file |
| MercyOne Newton Medical Center Newton, IA · (641) 792-1273 HC Vaccine Hepatitis B (Hepb) Adult Dosage 2 Dose Schedule Im | $310.70 | $478.00 | $126.48–$478.00 | 35% | Mar 31, 2026 source file |
| MercyOne Des Moines Medical Center Des Moines, IA · (515) 247-4436 HC Vaccine Hepatitis B (Hepb) Adult Dosage 2 Dose Schedule Im | $326.30 | $502.00 | $100.90–$502.00 | 35% | Mar 31, 2026 source file |
| MercyOne West Des Moines Medical Center West Des Moines, IA HC Vaccine Hepatitis B (Hepb) Adult Dosage 2 Dose Schedule Im | $502.00 | $502.00 | $100.90–$502.00 | — | Mar 31, 2026 source file |
Outpatient: lowest $165.34, median $318.50, highest $502.00 — a 3.0× difference within the same market.
As an inpatient, the same code is billed by 4 facilities here, median $318.50. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 3 of 4 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
Heplisav-B is a hepatitis B vaccine for adults that needs only two doses, one month apart, instead of three over six months.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).