RSV antibody shot (100 mg dose) cost in San Antonio, TX
In San Antonio-New Braunfels, TX, 6 hospitals list a cash price for RSV antibody shot for infants and toddlers, larger dose (1 mL, 100 mg): from $519.75 to $3,171.83, with a median of $3,171.83. The lowest listed price is at Medina Regional Hospital — $2,652.08 less than the median here. Across Texas, the median is $980.10 at 61 hospitals.
Cash prices at 6 facilities across 3 cities for code 90381, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 27, 2026; the hospital files themselves were last updated between Oct 14, 2025 and Sep 1, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in San Antonio-New Braunfels, TX.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list | File date |
|---|---|---|---|---|---|
| Medina Regional Hospital lowest Hondo, TX · (830) 426-7700 RSV MONOC ANTB SEASN 1 ML IM | $519.75 | $577.50 | $138.60–$577.50 | 10% | Jul 29, 2026 source file |
| University Health System San Antonio, TX · (210) 358-2000 HC PBB RSV MONOCLONAL ANTIBODY BEYFORTUS 1ML | $891.00 | $3,564.00 | $1,318.68–$8,910.00 | 75% | Oct 14, 2025 source file |
| University Health System San Antonio, TX · (210) 358-2000 Respiratory syncytial virus, monoclonal antibody, seasonal dose; 1 mL dosage, for intramuscular use | $1,001.79 | $4,007.16 | $1,482.65–$10,017.90 | 75% | Oct 14, 2025 source file |
| Methodist Hospital Stone Oak San Antonio, TX · (210) 638-2101 RSV MAB SEASONAL 1 ML IM | $3,171.83 | $3,171.83 | $158.59–$2,696.06 | — | Sep 1, 2026 source file |
| Methodist Hospital Helotes, TX · (210) 575-4000 Respiratory syncytial virus, monoclonal antibody, seasonal dose; 1 mL dosage, for intramuscular use | $3,171.83 | $3,171.83 | $630.77–$1,935.45 | — | Sep 1, 2026 source file |
| Metropolitan Methodist San Antonio, TX · (210) 575-4000 RSV MAB SEASONAL 1 ML IM | $3,171.83 | $3,171.83 | $158.59–$2,696.06 | — | Sep 1, 2026 source file |
| Stone Oak Rehab San Antonio, TX Respiratory syncytial virus, monoclonal antibody, seasonal dose; 1 mL dosage, for intramuscular use | $3,171.83 | $3,171.83 | $1,178.22 | — | Sep 1, 2026 source file |
| Stone Oak Rehab San Antonio, TX RSV MAB SEASONAL 1 ML IM | $3,171.83 | $3,171.83 | $158.59–$2,696.06 | — | Sep 1, 2026 source file |
| Metropolitan Methodist San Antonio, TX · (210) 575-4000 Respiratory syncytial virus, monoclonal antibody, seasonal dose; 1 mL dosage, for intramuscular use | $3,171.83 | $3,171.83 | $1,178.22 | — | Sep 1, 2026 source file |
| Methodist Hospital Helotes, TX · (210) 575-4000 RSV MAB SEASONAL 1 ML IM | $3,171.83 | $3,171.83 | $158.59–$3,171.83 | — | Sep 1, 2026 source file |
| Methodist Hospital Stone Oak San Antonio, TX · (210) 638-2101 Respiratory syncytial virus, monoclonal antibody, seasonal dose; 1 mL dosage, for intramuscular use | $3,171.83 | $3,171.83 | $1,178.22 | — | Sep 1, 2026 source file |
Outpatient: lowest $519.75, median $3,171.83, highest $3,171.83 — a 6.1× difference within the same market.
As an inpatient, the same code is billed by 2 facilities here, median $705.38. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 2 of 6 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at 1 it is below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
This is the larger dose (100 mg) of nirsevimab (Beyfortus), an antibody shot that protects infants from severe RSV. Babies weighing 5 kg (11 lb) or more in their first RSV season get this dose, and high-risk toddlers get two of them in their second season.
What the price covers
The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).