Vaccines CPT 90381 Inpatient — admitted to hospital

RSV antibody shot (100 mg dose) cost in Orlando, FL — inpatient

In Orlando-Kissimmee-Sanford, FL, 3 hospitals list a cash price for RSV antibody shot for infants and toddlers, larger dose (1 mL, 100 mg) as an inpatient: from $1,171.54 to $1,663.00, with a median of $1,171.54. The lowest listed price is at UF Health Leesburg Hospital and 1 other hospital. Across Florida, the median is $1,281.71 at 45 hospitals.

Cash prices at 3 facilities across 3 cities for code 90381, as an inpatient (admitted to hospital) . Collected Sep 23, 2026; the hospital files themselves were last updated between Mar 31, 2026 and Mar 31, 2026.

Lowest$1,171.54UF Health Leesburg Hospital + 1 more
Median$1,171.54half pay less
Highest$1,663.00in this market
Difference1.4×highest vs lowest

Where each hospital's price falls

Each dot is one hospital's cash price on a scale from the lowest to the highest in Orlando-Kissimmee-Sanford, FL.

median
Lowest $1,171.54Highest $1,663.00

Hospitals, cheapest first

HospitalCash price List priceInsurers payOff listFile date
UF Health Leesburg Hospital lowest Leesburg, FL · (352) 323-5762 BEYFORTUS 100 MG/ML IM SOSY $1,171.54 $2,130.07 $958.53–$1,476.14 45% Mar 31, 2026
source file
The Villages Regional Hospital lowest The Villages, FL · (352) 751-8000 BEYFORTUS 100 MG/ML IM SOSY $1,171.54 $2,130.07 $958.53–$1,767.96 45% Mar 31, 2026
source file
Nemours Childrens Hospital, Florida Orlando, FL · (407) 567-4000 NIRSEVIMAB-ALIP 100 MG/ML IM SOSY $1,663.00 $1,663.00 — — —
source file

Inpatient: lowest $1,171.54, median $1,171.54, highest $1,663.00 — a 1.4× difference within the same market.

As an outpatient, the same code is billed by 3 facilities here, median $1,171.54 — that is the price to compare if you are not being admitted.

Cash or insurance?

At 2 of 2 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.

What it is

This is the larger dose (100 mg) of nirsevimab (Beyfortus), an antibody shot that protects infants from severe RSV. Babies weighing 5 kg (11 lb) or more in their first RSV season get this dose, and high-risk toddlers get two of them in their second season.

What the price covers

The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).