Vaccines CPT 90381 Outpatient

RSV antibody shot (100 mg dose) cost in Buffalo, NY

In Buffalo-Cheektowaga, NY, 2 hospitals list a cash price for RSV antibody shot for infants and toddlers, larger dose (1 mL, 100 mg): from $1,539.00 to $1,656.52, with a median of $1,597.76. The lowest listed price is at Kaleida Health — $58.76 less than the median here. Across New York, the median is $1,033.54 at 46 hospitals.

Cash prices at 2 facilities for code 90381, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 27, 2026; the hospital files themselves were last updated between Apr 1, 2026 and Apr 1, 2026.

Lowest$1,539.00Kaleida Health
Median$1,597.76half pay less
Highest$1,656.52in this market
Difference1.1×highest vs lowest

Where each hospital's price falls

Each dot is one hospital's cash price on a scale from the lowest to the highest in Buffalo-Cheektowaga, NY.

median
Lowest $1,539.00Highest $1,656.52

Hospitals, cheapest first

HospitalCash price List priceInsurers payOff listFile date
Kaleida Health lowest Buffalo, NY · (716) 859-8620 Beyfortus 100Mg/1Ml Inj $1,539.00 $1,539.00 — — Apr 1, 2026
source file
Sisters of Charity Hospital Buffalo, NY · (716) 862-1000 NIRSEVIMAB-ALIP 100 MG/ML INTRAMUSCULAR SYRINGE $1,656.52 $1,656.52 $268.20–$596.00 — —
source file

Outpatient: lowest $1,539.00, median $1,597.76, highest $1,656.52 — a 1.1× difference within the same market.

As an inpatient, the same code is billed by 2 facilities here, median $1,597.76. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.

Cash or insurance?

At the one hospital here that publishes insurer rates for this code, the cash price is not below the highest rate a health plan has negotiated. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.

What it is

This is the larger dose (100 mg) of nirsevimab (Beyfortus), an antibody shot that protects infants from severe RSV. Babies weighing 5 kg (11 lb) or more in their first RSV season get this dose, and high-risk toddlers get two of them in their second season.

What the price covers

The price is for the vaccine dose. Giving the shot is usually a separate line (code 90471 for the first vaccine of the visit, 90472 for each additional one).

1 row held back from this comparison

It is priced below $1 or below a tenth of the national median for code 90381 ($980.10). Such a line is almost always a physician's fee billed separately, an assistant's share or a placeholder — a real charge, but not the price of the procedure itself.

Kaleida Health Buffalo, NYVfc Beyfortus 1Ml Inj $0.01 file