AFP test cost in Harrisburg, PA
In Harrisburg-Carlisle, PA, 6 hospitals list a cash price for alpha-fetoprotein (AFP) blood test: from $26.04 to $233.05, with a median of $60.66. The lowest listed price is at Penn State Health Holy Spirit Medical Center — $34.62 less than the median here. Across Pennsylvania, the median is $108.62 at 94 hospitals.
Cash prices at 6 facilities across 5 cities for code 82105, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 29, 2026; the hospital files themselves were last updated between Aug 6, 2026 and Aug 6, 2026.
Where each hospital's price falls
Each dot is one hospital's cash price on a scale from the lowest to the highest in Harrisburg-Carlisle, PA.
Hospitals, cheapest first
| Hospital | Cash price | List price | Insurers pay | Off list | File date |
|---|---|---|---|---|---|
| Penn State Health Holy Spirit Medical Center lowest Camp Hill, PA · (717) 763-2100 82105 Alpha Fetoprotein. Tech | $26.04 | $109.00 | $14.25–$87.20 | 76% | — source file |
| Penn State Health Holy Spirit Medical Center lowest Camp Hill, PA · (717) 763-2100 Maternal Serum AFP-QSTC Tech | $26.04 | $109.00 | $14.25–$87.20 | 76% | — source file |
| Penn State Health Holy Spirit Medical Center lowest Camp Hill, PA · (717) 763-2100 First Trimester Scrn, AFP Tech | $26.04 | $109.00 | $14.25–$87.20 | 76% | — source file |
| Penn State Health Holy Spirit Medical Center lowest Camp Hill, PA · (717) 763-2100 82105 Maternal Serum AFP -Quest Tech | $26.04 | $109.00 | $14.25–$87.20 | 76% | — source file |
| Penn State Health Holy Spirit Medical Center lowest Camp Hill, PA · (717) 763-2100 82105 ALPHA-FETOPROTEIN SERUM Tech | $26.04 | $109.00 | $14.25–$87.20 | 76% | — source file |
| Penn State Health Hampden Medical Center Enola, PA · (717) 981-9000 82105 Maternal Serum AFP -Quest Tech | $34.30 | $109.00 | $14.25–$87.20 | 69% | — source file |
| Penn State Health Hampden Medical Center Enola, PA · (717) 981-9000 82105 ALPHA-FETOPROTEIN SERUM Tech | $34.30 | $109.00 | $14.25–$87.20 | 69% | — source file |
| Penn State Health Hampden Medical Center Enola, PA · (717) 981-9000 First Trimester Scrn, AFP Tech | $34.30 | $109.00 | $14.25–$87.20 | 69% | — source file |
| Penn State Health Hampden Medical Center Enola, PA · (717) 981-9000 Maternal Serum AFP-QSTC Tech | $34.30 | $109.00 | $14.25–$87.20 | 69% | — source file |
| Penn State Health Hampden Medical Center Enola, PA · (717) 981-9000 82105 Alpha Fetoprotein. Tech | $34.30 | $109.00 | $14.25–$87.20 | 69% | — source file |
| Penn State Health Milton S. Hershey Medical Center Hershey, PA · (717) 531-8521 Alpha Fetoprotein. | $36.11 | $109.00 | $14.25–$87.20 | 67% | — source file |
| Penn State Health Milton S. Hershey Medical Center Hershey, PA · (717) 531-8521 ALPHA-FETOPROTEIN SERUM (SQ) | $36.11 | $109.00 | $14.25–$87.20 | 67% | — source file |
| Penn State Health Milton S. Hershey Medical Center Hershey, PA · (717) 531-8521 FIRST TRIMESTER SCRN, AFP | $36.11 | $109.00 | $14.25–$87.20 | 67% | — source file |
| Penn State Health Milton S. Hershey Medical Center Hershey, PA · (717) 531-8521 MATERNAL SERUM SCREEN1 (SQ) | $36.11 | $109.00 | $14.25–$87.20 | 67% | — source file |
| Penn State Health Milton S. Hershey Medical Center Hershey, PA · (717) 531-8521 ALPHA FETOPROTEIN (SQ) | $36.11 | $109.00 | $14.25–$87.20 | 67% | — source file |
| Penn State Health Milton S. Hershey Medical Center Hershey, PA · (717) 531-8521 Maternal Serum AFP-QSTC | $36.11 | $109.00 | $14.25–$87.20 | 67% | — source file |
| UPMC Pinnacle Hospitals Harrisburg, PA · (717) 782-3131 HC ALPHA FETOPROTEIN TUMOR MARKER | $85.20 | $142.00 | $16.60–$129.59 | 40% | — source file |
| UPMC Pinnacle Hospitals Harrisburg, PA · (717) 782-3131 HC ALPHA FETOPROTEIN-TRIPLE A | $85.20 | $142.00 | $16.60–$129.59 | 40% | — source file |
| UPMC Pinnacle Hospitals Harrisburg, PA · (717) 782-3131 HC AFP QUAD SCREEN PROFILE A | $85.20 | $142.00 | $16.60–$129.59 | 40% | — source file |
| UPMC Pinnacle Hospitals Harrisburg, PA · (717) 782-3131 HC ALPHA FETOPROTEIN | $85.20 | $142.00 | $16.60–$129.59 | 40% | — source file |
| UPMC Carlisle Carlisle, PA · (717) 249-1212 HC ALPHA FETOPROTEIN TUMOR MARKER | $85.20 | $142.00 | $16.60–$120.70 | 40% | — source file |
| UPMC Carlisle Carlisle, PA · (717) 249-1212 HC ALPHA FETOPROTEIN-TRIPLE A | $85.20 | $142.00 | $16.60–$120.70 | 40% | — source file |
| UPMC Carlisle Carlisle, PA · (717) 249-1212 HC AFP QUAD SCREEN PROFILE A | $85.20 | $142.00 | $16.60–$120.70 | 40% | — source file |
| UPMC Carlisle Carlisle, PA · (717) 249-1212 HC ALPHA FETOPROTEIN | $85.20 | $142.00 | $16.60–$120.70 | 40% | — source file |
| PAM Health Rehabilitation Hospital of Hampden Enola, PA Alpha-Fetoprotein Serum | $233.05 | $233.05 | $174.79 | — | Aug 6, 2026 source file |
Outpatient: lowest $26.04, median $60.66, highest $233.05 — a 8.9× difference within the same market.
As an inpatient, the same code is billed by 6 facilities here, median $60.66. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.
Cash or insurance?
At 5 of 6 hospitals that publish insurer rates for this code here, the cash price is below the highest rate a health plan has negotiated, and at none is it below every plan's rate. If you have insurance but have not met your deductible, you usually pay your plan's negotiated rate, which falls somewhere in the "Insurers pay" column. Paying cash can cost less, but a cash payment usually does not count toward your deductible. Ask the hospital for both numbers before you book.
What it is
An AFP test measures a protein made by the liver and by a developing baby. In adults it is used to watch for liver cancer in people with cirrhosis and to follow some testicular cancers.
What the price covers
The price usually covers running the test. The blood draw (36415) is often billed as a separate line.