Surgery and procedures CPT 45380 Outpatient

Colonoscopy with tissue sample in Harrisburg-Carlisle, PA

In Harrisburg-Carlisle, PA, 2 hospitals list a cash price for Colonoscopy with tissue sample: from $1,830.93 to $2,411.86, with a median of $2,121.40. The lowest listed price is at Penn State Health Holy Spirit Medical Center.

Cash prices at 3 facilities across 3 cities for code 45380, as an outpatient — the setting a self-pay patient normally buys. Collected Sep 23, 2026; the hospital files themselves were last updated between — and —.

Lowest$1,830.93Penn State Health Holy Spirit Medical Center
Median$2,121.40half pay less
Highest$2,411.86in this market
Difference1.3×highest vs lowest

Where each hospital's price falls

Each dot is one hospital's cash price on a scale from the lowest to the highest in Harrisburg-Carlisle, PA.

median
Lowest $1,830.93Highest $2,539.08
one sideboth sides

Hospitals, cheapest first

HospitalCash price List priceOff listFile date
Penn State Health Holy Spirit Medical Center lowest Camp Hill, PA 45380 COLONOSCOPY AND BIOPSY Tech $1,830.93 $7,664.00 76%
source file
Penn State Health Hampden Medical Center Enola, PA 45380 COLONOSCOPY AND BIOPSY Tech $2,411.86 $7,664.00 69%
source file
Penn State Health Milton S. Hershey Medical Center one side Hershey, PA 45380 Colonoscopy Right W/Biops $2,539.08 $7,664.00 67%
source file

Outpatient: lowest $1,830.93, median $2,121.40, highest $2,411.86 — a 1.3× difference within the same market.

One side of the body : lowest $2,539.08, median $2,539.08, highest $2,539.08.

The two groups are not comparable and are not averaged together: a price for both sides of the body covers twice the work. Merging them is how a single published "median" ends up far above what one side actually costs.

As an inpatient, the same code is billed by 2 facilities here, median $2,121.40. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.

As an inpatient, the same code is billed by 1 facility here, median $2,539.08. Inpatient and outpatient prices are not comparable and are kept on separate pages: the inpatient charge covers admission, not the same purchase.

What it is

This colonoscopy looks at the entire colon and takes one or more small tissue samples (biopsies) with tiny forceps. Biopsies can check for inflammation, infection or abnormal cells.

What the price covers

The facility price covers the procedure room and recovery. The gastroenterologist, anesthesia and the pathologist who examines the samples bill separately.